Indocollyre (Indometacin)

Indometacin inhibits cyclooxygenase enzymes (COX‑1 and COX‑2) in ocular tissues, which blocks the formation of prostaglandins that drive inflammation. By lowering prostaglandin levels, the drug reduces vascular permeability, edema, and pain, providing anti‑inflammatory relief directly at the site of application.

The dosing regimen for Indocollyre is determined by the prescribing clinician based on the severity of inflammation and the surgical context. Typical regimens involve one to several drops instilled into the affected eye(s) at prescribed intervals, but the exact schedule should follow the healthcare professional’s instructions.

Safety data for indometacin eye drops in pregnancy and lactation are limited. The product is classified as having an unknown pregnancy category, so it should only be used if the potential benefit justifies any possible risk to the fetus or infant. Consultation with a obstetrician or pediatrician is recommended.

To order Indocollyre, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details and any necessary import documentation.

Indocollyre (indometacin) belongs to the NSAID class, offering potent prostaglandin inhibition without the corticosteroid‑related risk of increased intra‑ocular pressure. Compared with steroid eye drops, it may have a lower risk of cataract formation but can cause local irritation. Choice of therapy depends on the clinical scenario and physician judgment.

Indocollyre should be stored at room temperature, below 25 °C, in its original container. Protect the solution from direct light and moisture. Do not freeze the product. Keep the vial tightly closed when not in use and discard any remaining solution after the labeled period once opened.

Indocollyre is applied as an eye drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid to form a pocket, and instill the prescribed number of drops into the conjunctival sac. Avoid touching the dropper tip to the eye or any surface to maintain sterility.

Serious risks include corneal ulceration or epithelial defects, severe allergic reactions such as angio‑edema, and a significant rise in intra‑ocular pressure that could threaten vision. Systemic absorption may also lead to typical NSAID‑related effects like gastrointestinal bleeding, especially when used with other NSAIDs.

Indocollyre should be avoided in individuals with a known hypersensitivity to indometacin or any NSAID, in eyes with active infection, and in patients with uncontrolled glaucoma or severe ocular surface disease. Caution is also advised for pregnant or breastfeeding women, and for those taking systemic anticoagulants without medical supervision.