Indofort (Indapamide)

Indapamide inhibits the sodium‑chloride symporter in the distal convoluted tubule, decreasing reabsorption of Na⁺ and Cl⁻. This causes natriuresis and diuresis, reducing extracellular fluid volume, while a modest vasodilatory effect lowers peripheral vascular resistance, together producing antihypertensive and diuretic actions.

The dosage of Indofort is determined by the prescribing clinician based on the patient’s condition, response, and renal function. Typical adult regimens range from 1.5 mg to 2.5 mg once daily, but the exact dose and frequency must be individualized and written on the prescription.

Indapamide is generally classified as a pregnancy category C medication, meaning risk cannot be ruled out. It should only be used if the potential benefit justifies the potential risk to the fetus. Use while breastfeeding is usually discouraged because the drug can be excreted in breast milk; alternative therapies are preferred.

To request Indofort, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Indapamide shares the sodium‑chloride symporter inhibition of classic thiazides but has a longer half‑life and a modest vasodilatory component, often resulting in a smoother blood‑pressure profile and lower incidence of metabolic side effects such as hyperglycaemia. Compared with hydrochlorothiazide, it may be preferred in patients who need both antihypertensive and diuretic effects with fewer electrolyte shifts.

Indofort tablets should be stored at temperatures below 25 °C, in the original container, protected from moisture and direct sunlight. Do not store in bathrooms or near heat sources, and keep out of reach of children to maintain product stability and potency.

Indofort is taken orally, usually once daily in the morning with or without food, as directed by the prescribing healthcare professional. The tablet should be swallowed whole with a glass of water; it should not be crushed, chewed, or split unless specifically advised.

The most serious adverse events include severe electrolyte disturbances (especially hypokalaemia and hyponatraemia), acute kidney injury, and rare allergic reactions such as Stevens‑Johnson syndrome or angio‑edema. Patients should be monitored for signs of dehydration, muscle weakness, or rash, and seek medical attention promptly if these occur.

Indofort is contraindicated in patients with known hypersensitivity to indapamide or other sulfonamide‑derived drugs, in those with anuria, severe renal impairment, or uncontrolled electrolyte imbalances. Caution is also advised for individuals with gout, hepatic disease, or those taking lithium, as the drug may exacerbate these conditions.