Product image of Indometacínový Vulm (Indometacin) supplied by GNH India

Indometacínový Vulm

Active Ingredient:
Indometacin
Origin:
EU

Indometacínový Vulm (Indometacin)

Indometacin, the active ingredient in Indometacínový Vulm, is a nonsteroidal anti‑inflammatory drug presented as a topical formulation for local use. It reduces pain and inflammation in musculoskeletal conditions such as arthritis and spinal disorders.
GNH India supplies Indometacínový Vulm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Vulm S.R.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Indometacin is indicated for conditions involving inflammation and pain in the musculoskeletal system.

  • Rheumatoid arthritis: reduces joint pain and swelling.
  • Osteoarthritis: alleviates pain and improves joint function.
  • Ankylosing spondylitis: diminishes spinal inflammation and discomfort.

How It Works

  • Indometacin inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis lowers inflammatory mediators at the site of application, providing analgesic and anti‑inflammatory effects in the affected tissues.

Side Effects

Indometacin may cause a range of adverse reactions, from mild skin irritation to rare but serious systemic events.

Common Side Effects

  • Local skin irritation: redness or itching at the application site.
  • Burning sensation: transient warmth or stinging.
  • Dry skin: mild desquamation.
  • Mild rash: limited erythema.
  • Pruritus: localized itching.
  • Eczema‑like changes: mild dermatitis.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): rapid onset of swelling, breathing difficulty.
  • Stevens‑Johnson syndrome: extensive skin blistering and mucosal involvement.
  • Toxic epidermal necrolysis: widespread skin detachment.
  • Severe skin ulceration: deep necrotic lesions.
  • Systemic NSAID toxicity: hepatic or renal impairment.
  • Hematologic abnormalities: rare blood dyscrasias.

Precautions & Warnings

Before using Indometacínový Vulm, consider the following safety measures.

  • Assess renal function: NSAIDs may impair kidney clearance.
  • Monitor gastrointestinal risk: increased chance of ulceration or bleeding.
  • Avoid in known hypersensitivity: discontinue if allergic signs appear.
  • Use with caution in cardiovascular disease: may elevate thrombotic risk.
  • Avoid concurrent use with other NSAIDs or anticoagulants: heightened bleeding potential.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Indometacin can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Methotrexate: reduced clearance leading to toxicity.
  • Lithium: elevated serum lithium concentrations.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible renal function compromise.
  • Corticosteroids: additive risk of gastrointestinal ulceration.
  • SSRIs: enhanced bleeding tendency.

Frequently Asked Questions

Indometacínový Vulm is a topical NSAID that is employed to relieve pain and reduce inflammation in musculoskeletal disorders such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is applied directly to the affected skin area to target local symptoms.

Indometacin blocks the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for producing prostaglandins—molecules that promote inflammation, pain, and fever. By lowering prostaglandin levels at the site of application, indometacin diminishes the inflammatory response and provides analgesia.

The specific dose and frequency of application are determined by the prescribing healthcare professional based on the severity of the condition, the size of the treatment area, and patient factors. Patients should follow the prescriber’s instructions and the product label.

Safety data for topical indometacin in pregnancy and lactation are limited. Healthcare providers generally weigh the potential benefits against possible risks before prescribing. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternative options with their clinician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Indometacínový Vulm contains indometacin, which is a potent COX inhibitor and may provide stronger anti‑inflammatory effects than some other topical NSAIDs such as diclofenac or ibuprofen. Choice of product depends on the clinician’s assessment of efficacy, tolerability, and patient‑specific factors.

Store the product at room temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

The gel or cream is applied to clean, dry skin over the affected area. A thin layer is spread gently and massaged until absorbed. The frequency and duration of use are set by the prescriber, typically ranging from once to several times daily.

Serious risks include severe allergic reactions such as anaphylaxis, life‑threatening skin conditions like Stevens‑Johnson syndrome or toxic epidermal necrolysis, and systemic toxicity affecting liver or kidneys. Patients should seek immediate medical attention if they notice extensive rash, blistering, or systemic symptoms.

Individuals with known hypersensitivity to indometacin or any component of the formulation should avoid use. Patients with active gastrointestinal ulcers, severe renal or hepatic impairment, uncontrolled cardiovascular disease, or those taking interacting medications (e.g., anticoagulants, methotrexate, lithium) should consult their healthcare provider before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.