Indometacin Tillomed Laboratories (Indometacin)

Indometacin works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the synthesis of prostaglandins. Reduced prostaglandin levels lead to decreased inflammation, pain signaling, and fever in affected tissues.

The appropriate dose of Indometacin is determined by the prescribing healthcare professional based on the specific indication, severity of symptoms, patient age, renal and hepatic function, and any concomitant medications.

Indometacin’s pregnancy category is listed as unknown, and safety data are limited. It is generally avoided during pregnancy, especially in the third trimester, and during breastfeeding unless the benefit outweighs potential risks, as advised by a physician.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Indometacin is a potent non‑selective NSAID with a relatively rapid onset of action. Compared with ibuprofen or naproxen, it may provide stronger anti‑inflammatory effects but also carries a higher risk of gastrointestinal and renal adverse events, requiring careful monitoring.

Indometacin tablets should be stored at temperatures below 25 °C, in the original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use after the expiry date.

Indometacin is taken orally, usually with a full glass of water. It may be taken with food or milk to lessen stomach irritation, but the exact timing should follow the prescribing clinician’s instructions.

Serious risks include gastrointestinal ulceration or bleeding, liver injury, acute kidney impairment, severe skin reactions such as Stevens‑Johnson syndrome, and heightened blood‑pressure effects. Patients should seek immediate medical attention if they notice unusual bleeding, jaundice, swelling, or rash.

Indometacin should be avoided in individuals with known hypersensitivity to indometacin or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, significant renal or hepatic impairment, and in patients in the third trimester of pregnancy unless specifically directed by a physician.