Indoxyl (Clindamycin, Benzoyl Peroxide)

Clindamycin, one of the active ingredients, binds to the 50S ribosomal subunit of Cutibacterium acnes, blocking protein synthesis and halting bacterial growth. This antibacterial action reduces the inflammatory response that contributes to acne development.

The dosing regimen for Indoxyl is determined by the prescribing clinician. Typically, a thin layer is applied to the affected skin once or twice daily, but the exact frequency, amount, and treatment duration should follow the healthcare professional’s instructions.

Safety data for topical clindamycin/benzoyl peroxide in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting treatment.

To request Indoxyl, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Indoxyl combines an antibiotic with a keratolytic, offering both antibacterial and comedolytic effects in a single formulation. Compared with retinoids, it may cause less irritation but lacks the strong cell‑turnover benefits; compared with oral antibiotics, it provides localized action with lower systemic exposure.

Indoxyl should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from excessive moisture, direct sunlight, and heat to maintain stability and potency throughout its shelf life.

Indoxyl is applied topically to clean, dry skin. A thin film is spread over the affected area, usually once or twice daily, as directed by a healthcare professional. Hands should be washed before and after application to avoid accidental contact with eyes or mucous membranes.

Serious adverse reactions, although rare, include severe contact dermatitis, extensive skin swelling, and photosensitivity leading to severe sunburn. If any of these occur, discontinue use immediately and seek medical attention.

Indoxyl should be avoided by individuals with known hypersensitivity to clindamycin, benzoyl peroxide, or any component of the formulation. It is also contraindicated on severely damaged, broken, or inflamed skin, and should be used with caution in patients with a history of allergic skin reactions.