Product image of Infacol (Simeticone) supplied by GNH India

Infacol

Active Ingredient:
Simeticone
Origin:
EU

Infacol (Simeticone)

Simeticone, the active ingredient in Infacol, is an antiflatulent presented as an oral liquid for oral use. It reduces gas bubbles in the gastrointestinal tract, providing relief from colic and flatulence in infants and other patients experiencing excessive gas. The medication is available over‑the‑counter in the European market and is intended for short‑term relief of gas‑related discomfort.

GNH India supplies Infacol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Gyógyszergyár Zrt

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Indications & Clinical Uses

  • Infacol, a simeticone‑based antiflatulent, acts on gastrointestinal gas accumulation.
  • Infant colic: reduces discomfort caused by trapped gas in infants, helping to soothe prolonged crying episodes.
  • Infant gas: alleviates excessive intestinal gas and associated irritability in newborns and young babies.
  • Adult flatulence: provides rapid relief from bloating, pressure and gas‑related discomfort in adults.

How It Works

  • Simeticone acts as a surfactant that lowers the surface tension of gas bubbles within the gastrointestinal lumen. By reducing interfacial tension, the bubbles coalesce into larger bubbles that are more easily expelled through belching or flatulence, thereby decreasing abdominal distension and discomfort without being absorbed systemically.

Side Effects

Simeticone is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects

  • Mild nausea or stomach upset
  • Transient vomiting
  • Diarrhoea or loose stools
  • Unpleasant taste in the mouth
  • Mild oral irritation
  • Increased flatulence after initial dose

Serious or Rare Side Effects

  • Allergic reaction (rash, itching, swelling)
  • Anaphylaxis (difficulty breathing, throat swelling)
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Persistent vomiting or severe abdominal pain
  • Hypersensitivity leading to angio‑edema

Precautions & Warnings

When using Infacol, consider the following precautions.

  • Age limitation: Use in infants only under medical guidance and not in newborns younger than two weeks unless advised.
  • Dosage adherence: Do not exceed the recommended amount indicated by a healthcare professional.
  • Underlying conditions: Seek medical advice if symptoms persist beyond a few days or worsen.
  • Hypersensitivity: Discontinue use and consult a clinician if any signs of allergic reaction appear.
  • Drug interactions: Inform the prescriber of all concurrent medications, especially those requiring gastric absorption.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Simeticone has low systemic absorption, yet certain co‑administered drugs may be affected.

Major Interactions (Avoid)

  • None identified: Simeticone does not exhibit clinically significant major drug interactions.
  • Concurrent use with other antiflatulents: may increase gastrointestinal side effects.

Moderate Interactions (Monitor Closely)

  • Tetracycline antibiotics: Simeticone may reduce absorption if taken simultaneously; separate dosing by at least 2 hours.
  • Iron or calcium supplements: possible decreased mineral absorption; stagger administration.
  • Levothyroxine: potential reduction in thyroid hormone absorption; advise spacing doses.
  • Antifungal agents (e.g., ketoconazole): may experience reduced bioavailability when co‑administered.

Frequently Asked Questions

Infacol is an over‑the‑counter product that contains the antiflatulent simeticone. It is used to relieve gas‑related discomfort, including colic in infants and flatulence or bloating in older children and adults. By helping gas bubbles coalesce, it eases abdominal pressure and reduces crying or pain associated with trapped gas.

Simeticone works as a surfactant that lowers the surface tension of gas bubbles in the gastrointestinal tract. This causes small bubbles to merge into larger ones that can be expelled more easily through belching or flatulence, thereby decreasing abdominal distension and discomfort without being absorbed into the bloodstream.

The appropriate dose of Infacol is determined by a healthcare professional based on the patient’s age, weight and clinical condition. Prescribers provide specific instructions on the number of drops or millilitres to administer and the frequency of dosing. Always follow the prescriber’s guidance and the product label.

Limited clinical data are available on the use of simeticone during pregnancy or lactation. Because the compound is minimally absorbed, it is generally considered low risk, but pregnant or nursing individuals should consult their physician before using Infacol to ensure it is appropriate for their specific situation.

To order Infacol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Infacol’s active ingredient, simeticone, is chemically identical to dimethicone found in many other antiflatulents. Compared with activated charcoal or herbal remedies, simeticone works by physically altering gas bubbles rather than absorbing toxins, offering a rapid and well‑tolerated effect with minimal systemic exposure. Efficacy and safety profiles are comparable to other simeticone‑based products.

Infacol should be stored at ambient temperature, preferably below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from moisture and direct sunlight, and keep it out of reach of children. Do not freeze the product, and discard any solution that appears discoloured or contains particles.

Infacol is administered orally, typically as drops or a measured liquid dose. The prescribed amount is placed directly into the infant’s mouth, often using the supplied dropper, and can be given with or without food. For older children or adults, the same oral liquid form is measured with a calibrated spoon or syringe as directed by a healthcare professional.

While Infacol is generally safe, serious adverse reactions can include allergic responses such as rash, itching, swelling, or anaphylaxis. Rarely, severe skin reactions like Stevens‑Johnson syndrome may occur. If any signs of hypersensitivity, persistent vomiting, or severe abdominal pain develop, discontinue use and seek immediate medical attention.

Infacol should be avoided in individuals with a known hypersensitivity to simeticone or any of the product’s excipients. It is not recommended for newborns younger than two weeks unless specifically advised by a physician. Patients with persistent gastrointestinal symptoms that have not been evaluated should consult a healthcare professional before using the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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