Product image of Infalin Duo (Ciprofloxacin, Fluocinolone Acetonide) supplied by GNH India

Infalin Duo

Active Ingredient:
Ciprofloxacin, Fluocinolone Acetonide
Origin:
EU

Infalin Duo (Ciprofloxacin, Fluocinolone Acetonide)

Ciprofloxacin, the active ingredient in Infalin Duo, is a fluoroquinolone antibiotic presented as a topical otic preparation for ear use. It treats bacterial ear infections such as otitis externa in both adults and children. Fluocinolone acetonide, also present, provides anti‑inflammatory action to reduce swelling and pain.

GNH India supplies Infalin Duo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Salvat, S.A.

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Indications & Clinical Uses

Infalin Duo combines an antibiotic and a corticosteroid to address bacterial and inflammatory conditions of the external ear.

  • Otitis externa: reduces bacterial load and inflammation, promoting faster resolution of infection.
  • Acute bacterial ear infection: provides targeted antimicrobial activity while controlling local swelling.
  • Chronic ear canal inflammation: helps manage persistent inflammation after infection clearance.

How It Works

  • Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, blocking DNA replication and leading to bacterial cell death. Fluocinolone acetonide binds to glucocorticoid receptors in ear tissues, suppressing inflammatory cytokine production and reducing edema and pain.

Side Effects

Infalin Duo may cause local or systemic adverse reactions.

Common Side Effects

  • Ear discomfort or mild burning sensation.
  • Itching or mild irritation of the ear canal.
  • Temporary hearing changes or muffled sound.
  • Mild headache.
  • Local dryness or flaking skin.

Serious or Rare Side Effects

  • Allergic reaction such as rash, swelling, or anaphylaxis.
  • Ototoxicity leading to permanent hearing loss.
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome).
  • Vision changes if medication spreads to the eye.
  • Unusual bleeding or bruising.

Precautions & Warnings

Before using Infalin Duo, consider the following safety measures.

  • Assess tympanic membrane integrity: avoid use if perforation is present.
  • Hypersensitivity: discontinue if allergic reaction occurs.
  • Viral infections: do not use unless bacterial superinfection is confirmed.
  • Monitor for signs of ototoxicity, especially with prolonged use.
  • Avoid concurrent ototoxic ear preparations.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Infalin Duo may interact with other medications; awareness helps prevent complications.

Major Interactions (Avoid)

  • Concurrent ototoxic ear drops (e.g., aminoglycoside preparations): increased risk of hearing loss.
  • Systemic fluoroquinolones: additive risk of tendon toxicity.

Moderate Interactions (Monitor Closely)

  • Corticosteroid eye drops: potential for increased systemic steroid exposure.
  • Anticoagulants: rare increase in bleeding risk with systemic absorption.
  • Non‑steroidal anti‑inflammatory drugs: may heighten gastrointestinal irritation if absorbed.

Frequently Asked Questions

Infalin Duo is a combination ear preparation that treats bacterial infections of the external ear, such as otitis externa, and reduces associated inflammation. It is applied directly into the ear canal to target the infection and swelling locally.

Ciprofloxacin interferes with bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication. By blocking these enzymes, the drug prevents bacterial growth and leads to bacterial cell death, helping to clear the infection.

The specific dosing regimen for Infalin Duo is determined by the prescribing healthcare professional based on the patient’s age, severity of infection, and clinical response. Patients should follow the prescriber’s instructions precisely.

Safety data for Infalin Duo in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks before prescribing it to pregnant or nursing individuals.

To request Infalin Duo, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Infalin Duo combines a fluoroquinolone antibiotic with a corticosteroid, offering both antimicrobial and anti‑inflammatory effects in a single formulation. Compared with single‑agent ear drops, it can reduce the need for additional anti‑inflammatory medication and may provide faster symptom relief.

Infalin Duo should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight to maintain product stability.

Infalin Duo is applied directly into the affected ear canal using the supplied dropper. The patient should lie with the treated ear facing upward, instill the prescribed number of drops, and remain in that position for a few minutes to ensure even distribution.

Serious risks include allergic reactions such as rash, swelling, or anaphylaxis, and ototoxicity that could lead to permanent hearing loss, especially if used with other ototoxic agents or in patients with a perforated tympanic membrane.

Infalin Duo should not be used by individuals with known hypersensitivity to ciprofloxacin, fluocinolone acetonide, or any component of the formulation, nor in patients with a perforated eardrum unless specifically directed by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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