Product image of Infanrix Polio (Pertussis Filamentous Haemagglutinin Adsorbed On Aluminium Hydroxide, Hydrated, Pertussis Toxoid Ads) supplied by GNH India

Infanrix Polio

Active Ingredient:
Pertussis Filamentous Haemagglutinin Adsorbed On Aluminium Hydroxide, Hydrated, Pertussis Toxoid Ads
Origin:
EU

Infanrix Polio (Pertussis Filamentous Haemagglutinin Adsorbed On Aluminium Hydroxide, Hydrated, Pertussis Toxoid Ads)

Diphtheria toxoid, tetanus toxoid, acellular pertussis, inactivated poliovirus vaccine, the active ingredient in Infanrix Polio, is a vaccine presented as an injectable solution for intramuscular use. It induces active immunity against diphtheria, tetanus, pertussis and poliomyelitis in infants and young children. It is routinely administered as part of national immunisation schedules to protect children from these serious bacterial and viral diseases.

GNH India supplies Infanrix Polio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, ensuring quality‑controlled distribution and regulatory compliance across multiple markets.

Manufacturer / TM Owner

Glaxosmithkline Biologicals S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Infanrix Polio is a combination vaccine that provides active immunisation against several bacterial and viral pathogens.

  • Diphtheria: prevents diphtheria infection by stimulating protective antibodies.
  • Tetanus: prevents tetanus disease through antibody formation.
  • Pertussis: reduces risk of whooping cough by inducing immunity.
  • Poliomyelitis: protects against poliovirus‑induced paralysis by generating neutralising antibodies.

How It Works

  • Infanrix Polio contains purified diphtheria toxoid, tetanus toxoid, acellular pertussis antigens (including filamentous haemagglutinin and pertussis toxoid) adsorbed onto aluminium hydroxide, and inactivated poliovirus strains. After intramuscular injection, the toxoids and viral particles are taken up by antigen‑presenting cells, processed and presented to helper T‑cells, which stimulate B‑cell production of specific IgG antibodies. The aluminium adjuvant enhances the immune response, leading to long‑lasting protective immunity.

Side Effects

Infanrix Polio may be associated with local and systemic reactions following injection.

Common Side Effects

  • Pain, redness or swelling at the injection site.
  • Low‑grade fever within 24‑48 hours.
  • Irritability or reduced appetite in infants.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) requiring immediate medical attention.
  • High fever or seizures occurring shortly after vaccination.
  • Persistent crying, hypotonic hyporesponsive episode, or encephalopathy, which are rare but warrant prompt evaluation.

Precautions & Warnings

Before administering Infanrix Polio, consider the following precautions.

  • Assess prior allergic reactions: verify no severe hypersensitivity to any vaccine component.
  • Delay vaccination if moderate or severe acute illness is present.
  • Observe for 15 minutes post‑injection: monitor for immediate allergic reactions.
  • Avoid use in individuals with known immunodeficiency without specialist advice.
  • Do not co‑administer with live vaccines at the same site.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Infanrix Polio may interact with other medicines or vaccines.

Major Interactions (Avoid)

  • Live vaccines: concurrent administration may reduce immunogenicity of live vaccines.
  • Immunoglobulin therapy: may interfere with vaccine response if given within 2 weeks.
  • Blood products: may diminish antibody development if administered shortly after vaccination.

Moderate Interactions (Monitor Closely)

  • Antipyretics: may mask fever, but do not affect immune response.
  • Corticosteroids: high‑dose may blunt antibody production, monitor titres.
  • Concurrent administration with other injectable vaccines: follow recommended intervals to avoid local reactions.

Frequently Asked Questions

Infanrix Polio is a combination vaccine used to protect infants and young children against four serious diseases: diphtheria, tetanus, pertussis (whooping cough) and poliomyelitis. By stimulating the immune system to produce specific antibodies, it helps prevent infection and the severe complications associated with each pathogen.

The vaccine contains toxoid forms of diphtheria and tetanus, acellular pertussis antigens, and inactivated poliovirus, all adsorbed onto aluminium hydroxide. After injection, antigen‑presenting cells process these components, activating T‑cells and prompting B‑cells to generate IgG antibodies. The aluminium adjuvant amplifies this response, creating durable immunity.

The dose and schedule of Infanrix Polio are determined by the prescribing healthcare professional based on national immunisation guidelines. Typically, the vaccine is given as a series of intramuscular injections in the thigh or upper arm of infants, but exact timing and number of doses should follow the clinician’s recommendation.

Infanrix Polio is generally not administered to pregnant women because it is intended for infant immunisation. Limited data are available regarding its safety in pregnancy, so it is usually avoided unless a clear benefit outweighs potential risks. Breastfeeding mothers may receive the vaccine, but they should discuss any concerns with their healthcare provider.

To order Infanrix Polio, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and any necessary import documentation.

Infanrix Polio combines diphtheria, tetanus, acellular pertussis and inactivated poliovirus antigens in a single injection, reducing the number of separate shots required. Compared with older whole‑cell pertussis vaccines, the acellular formulation tends to cause fewer local reactions while maintaining protective efficacy. It aligns with many national immunisation schedules that favour combined DTaP‑IPV products.

Infanrix Polio must be stored at 2‑8 °C (refrigerated) and protected from light. The vial should remain in its original packaging, should not be frozen, and must not be shaken vigorously. If the vaccine has been exposed to temperatures outside this range, it should be discarded according to the supplier’s guidelines.

The vaccine is given as an intramuscular injection, usually into the anterolateral thigh of infants or the deltoid muscle of older children. Administration is performed by a qualified healthcare professional using aseptic technique. The injection site should be observed for a short period after vaccination to monitor for immediate reactions.

While rare, serious adverse events can include severe allergic reactions (anaphylaxis), high‑grade fever, seizures, or neurological events such as encephalopathy. Caregivers should seek immediate medical attention if the child experiences difficulty breathing, persistent high fever, prolonged crying, or any signs of a severe reaction after vaccination.

Infanrix Polio should be avoided in individuals with a known severe allergy to any component of the vaccine, including aluminium hydroxide or the specific toxoids. It is also contraindicated in persons with a history of severe anaphylactic reaction to a previous dose of the same vaccine. Consultation with a healthcare professional is essential for those with immunodeficiency or other special conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.