Product image of Infanrix Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Pertussis Filamentous Haemagglutinin Adsorbed On A) supplied by GNH India

Infanrix Polio

Active Ingredient:
Poliovirus (Inactivated) Type 3 (Saukett Strain), Pertussis Filamentous Haemagglutinin Adsorbed On A
Origin:
EU

Infanrix Polio (Poliovirus (Inactivated) Type 3 (Saukett Strain), Pertussis Filamentous Haemagglutinin Adsorbed On A)

Poliovirus (Inactivated) Type 3 (Saukett Strain) and Pertussis Filamentous Haemagglutinin, the active ingredients in Infanrix Polio, are a vaccine presented as an injectable formulation for intramuscular use. It induces protective immunity against poliovirus type 3 and pertussis in infants and children.

GNH India supplies Infanrix Polio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global immunization programs, including cold‑chain logistics and comprehensive documentation for seamless distribution.

Manufacturer / TM Owner

Glaxosmithkline As

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Indications & Clinical Uses

Infanrix Polio is used to prevent infections caused by poliovirus type 3 and pertussis, as part of routine childhood immunization.

  • Poliomyelitis (Polio): prevents poliomyelitis caused by poliovirus type 3.
  • Pertussis (Whooping Cough): prevents pertussis infection.
  • Diphtheria: provides immunity against diphtheria toxin.
  • Tetanus: provides protection against tetanus toxin.

How It Works

  • Infanrix Polio contains inactivated poliovirus type 3 particles and purified pertussis filamentous haemagglutinin adsorbed onto an adjuvant. After intramuscular injection, the antigens are taken up by antigen‑presenting cells, stimulating B‑cell and T‑cell responses that generate neutralising antibodies against poliovirus and antibodies that block pertussis adhesion, establishing active immunity. The adjuvant enhances the immune response, ensuring long‑lasting protection after the primary series.

Side Effects

Infanrix Polio may be associated with local and systemic reactions following injection.

Common Side Effects

  • Injection site pain.
  • Redness at the injection site.
  • Swelling at the injection site.
  • Low‑grade fever.
  • Irritability.
  • Decreased appetite.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Seizure.
  • High fever.
  • Persistent crying.
  • Encephalopathy.
  • Guillain‑Barré syndrome.

Precautions & Warnings

Before administering Infanrix Polio, consider the following precautions.

  • Age restriction: not administered to infants under 6 weeks.
  • Previous allergic reaction: avoid if severe allergy to any vaccine component.
  • Immunocompromised patients: consult healthcare provider before vaccination.
  • Concurrent immunoglobulin therapy: may diminish vaccine efficacy.
  • Pregnancy: safety not established; weigh benefits and risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Infanrix Polio can interact with other therapies; review the following.

Major Interactions (Avoid)

  • Immunoglobulin or blood products administered within 4 weeks: may blunt vaccine efficacy.
  • Live viral vaccines given within 4 weeks: increased risk of adverse events.
  • Antipyretics taken before vaccination: may reduce immune response.

Moderate Interactions (Monitor Closely)

  • Concurrent administration with other inactivated vaccines: monitor for increased reactogenicity.
  • Use of systemic corticosteroids: may attenuate antibody production.
  • Severe febrile illness at the time of vaccination: postpone dose.

Frequently Asked Questions

Infanrix Polio is a combination vaccine indicated for the prevention of poliomyelitis caused by poliovirus type 3 and for protection against pertussis (whooping cough) in infants and young children as part of routine immunisation schedules.

The vaccine contains inactivated poliovirus type 3 particles and purified pertussis filamentous haemagglutinin. After intramuscular injection, these antigens stimulate the immune system to produce specific antibodies that neutralise poliovirus and block pertussis adhesion, thereby establishing active immunity.

The dosage and schedule of Infanrix Polio are determined by the prescribing healthcare professional based on national immunisation guidelines and the patient’s age. The prescriber sets the exact amount and timing of each injection.

Safety data for Infanrix Polio in pregnancy are limited, and the vaccine is generally not recommended unless the potential benefit outweighs the risk. Limited information is available for breastfeeding mothers, but the vaccine is not expected to pose a risk to the infant.

To place an order, submit an enquiry on the Infanrix Polio product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and necessary import documentation.

Infanrix Polio combines inactivated poliovirus type 3 with pertussis antigens, offering dual protection in a single injection. Compared with monovalent polio vaccines, it reduces the number of injections required but follows similar safety and efficacy principles for poliovirus immunity.

Infanrix Polio must be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. The vaccine should be kept in its original packaging until use to maintain potency.

The vaccine is given by a single intramuscular injection, typically into the anterolateral thigh in infants or the deltoid muscle in older children, according to the immunisation schedule recommended by health authorities.

Serious but rare adverse events include severe allergic reactions (anaphylaxis), seizures, high‑grade fever, encephalopathy, and Guillain‑Barré syndrome. Any signs of a serious reaction should be reported to a healthcare professional immediately.

Infanrix Polio should be avoided in individuals with a known severe allergy to any vaccine component, in infants younger than the approved age, and in persons who have experienced a severe reaction to a previous dose of the same vaccine.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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