Product image of Infectocef Saft (Cefaclor Monohydrate) supplied by GNH India

Infectocef Saft

Active Ingredient:
Cefaclor Monohydrate
Origin:
EU

Infectocef Saft (Cefaclor Monohydrate)

Cefaclor, the active ingredient in Infectocef Saft, is a second‑generation cephalosporin presented as an oral suspension for oral use. It treats bacterial infections such as acute otitis media, pharyngitis, sinusitis, bronchitis and urinary tract infections in children and adults, and is indicated for use in both pediatric and adult populations.

GNH India supplies Infectocef Saft as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU regulatory standards and is distributed to healthcare providers across multiple regions.

Manufacturer / TM Owner

Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim

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Indications & Clinical Uses

  • Cefaclor is a second‑generation cephalosporin antibiotic that targets bacterial infections of the respiratory and urinary tracts.
  • Acute otitis media: resolves middle‑ear infection caused by susceptible bacteria.
  • Pharyngitis / tonsillitis: reduces bacterial load and alleviates throat symptoms.
  • Sinusitis: treats acute bacterial sinus infection.
  • Bronchitis: helps clear bacterial bronchial infection.
  • Urinary tract infections: clears susceptible uropathogens.

How It Works

  • Cefaclor inhibits bacterial cell‑wall synthesis by binding to penicillin‑binding proteins on the inner surface of the bacterial membrane. This binding interferes with the cross‑linking of peptidoglycan strands, weakening the cell wall and leading to osmotic lysis of susceptible Gram‑positive and Gram‑negative organisms.

Side Effects

Cefaclor may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Diarrhea: loose stools occurring during treatment.
  • Nausea: feeling of unease or urge to vomit.
  • Vomiting: expulsion of stomach contents.
  • Rash: mild skin redness or itching.

Serious or Rare Side Effects

  • Anaphylaxis: severe, potentially life‑threatening allergic reaction.
  • Clostridioides difficile‑associated colitis: severe inflammation of the colon.
  • Stevens‑Johnson syndrome: rare, serious skin and mucous membrane disorder.

Precautions & Warnings

  • When prescribing or dispensing Cefaclor, consider the following precautions to ensure safe use.
  • Allergy assessment: verify no known hypersensitivity to cephalosporins or penicillins.
  • Renal function monitoring: adjust dosing in patients with impaired kidney function.
  • Gastrointestinal disease: use cautiously in patients with a history of colitis.
  • Neonatal use: avoid in neonates for certain infections unless specifically indicated.
  • Pregnancy and lactation: discuss risk‑benefit with the prescriber before use.
  • Store at below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Cefaclor can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Probenecid: reduces renal excretion of cefaclor, increasing plasma levels.
  • Aminoglycosides: combined use may increase risk of nephrotoxicity.
  • Warfarin: potential for increased anticoagulant effect and INR.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: possible reduction in contraceptive effectiveness.
  • Antacids containing aluminum or magnesium: may decrease cefaclor absorption.
  • Loop diuretics: monitor electrolytes as cefaclor can affect renal handling.

Frequently Asked Questions

Infectocef Saft contains cefaclor, a second‑generation cephalosporin indicated for the treatment of bacterial infections such as acute otitis media, pharyngitis, sinusitis, bronchitis and urinary tract infections. It is prescribed for patients who require an oral antibiotic that covers common Gram‑positive and Gram‑negative pathogens.

Cefaclor works by binding to penicillin‑binding proteins on bacterial cell walls, inhibiting the final steps of peptidoglycan synthesis. This disruption weakens the cell wall, leading to osmotic lysis and death of susceptible bacteria, thereby clearing the infection.

The dosage of Infectocef Saft is determined by the prescribing clinician based on the type and severity of infection, the patient’s age, weight, and renal function. The prescriber will provide specific instructions on how much suspension to take and how often.

Safety data for cefaclor in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant. Patients who are pregnant, planning to become pregnant, or breastfeeding should discuss the decision with their healthcare provider.

To order Infectocef Saft, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Cefaclor, as a second‑generation cephalosporin, offers broader coverage against certain Gram‑negative organisms compared with first‑generation agents like amoxicillin. It is generally more stable against beta‑lactamase enzymes, but may be less effective against some resistant strains where newer agents such as third‑generation cephalosporins or macrolides are preferred.

Infectocef Saft should be stored at temperatures below 25 °C, in its original container, protected from moisture and direct light. The suspension should be shaken gently before each use to ensure uniform concentration, and any unused portion should be discarded after the labeled shelf‑life expires.

Infectocef Saft is taken orally as a liquid suspension. The prescribed dose should be measured with a calibrated dosing spoon or oral syringe provided with the product. It can be taken with or without food, unless the prescriber advises otherwise.

The most serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and rare skin disorders like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they develop symptoms such as difficulty breathing, severe rash, or persistent diarrhea.

Infectocef Saft should not be used by individuals with a known hypersensitivity to cefaclor, other cephalosporins, or penicillins. It is also contraindicated in neonates for certain infections and should be avoided in patients with a history of severe colitis unless specifically indicated by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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