Product image of Infectociprocort (Ciprofloxacin, Fluocinolone Acetonide) supplied by GNH India

Infectociprocort

Active Ingredient:
Ciprofloxacin, Fluocinolone Acetonide
Origin:
EU

Infectociprocort (Ciprofloxacin, Fluocinolone Acetonide)

Ciprofloxacin, the active ingredient in Infectociprocort, is a fluoroquinolone antibiotic presented as a topical ear preparation for auricular use. Combined with the corticosteroid fluocinolone acetonide, it treats bacterial ear infections and reduces inflammation in patients with external otitis and related conditions.

GNH India supplies Infectociprocort as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim

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Indications & Clinical Uses

Infectociprocort acts on bacterial and inflammatory pathways in the external ear.

  • External otitis: eliminates causative bacteria and lessens canal inflammation.
  • Bacterial otitis externa: provides broad‑spectrum antibacterial coverage while soothing swelling.
  • Ear inflammation with infection: delivers combined antimicrobial and anti‑inflammatory action to improve symptoms and promote healing.

How It Works

  • Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, blocking DNA replication and leading to bacterial cell death. Fluocinolone acetonide binds intracellular glucocorticoid receptors, altering gene transcription to suppress pro‑inflammatory cytokine production, reduce leukocyte migration, and stabilize cellular membranes, thereby providing local anti‑inflammatory and immunosuppressive effects.

Side Effects

Infectociprocort may cause local and systemic reactions.

Common Side Effects

  • Ear discomfort or mild burning sensation.
  • Itching or irritation at the application site.
  • Temporary alteration in hearing perception.
  • Mild headache.
  • Local redness or swelling.
  • Dryness of the ear canal.

Serious or Rare Side Effects

  • Allergic reaction with rash, swelling, or difficulty breathing.
  • Ototoxicity leading to permanent hearing loss.
  • Severe ear pain or ulceration.
  • Vestibular disturbances such as dizziness or vertigo.
  • Secondary fungal or bacterial infection of the ear.
  • Systemic hypersensitivity including fever and joint pain.

Precautions & Warnings

Use Infectociprocort only as prescribed and observe the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: consider potential exposure to the infant.
  • Age: limit use in children unless directed by a physician.
  • Perforated tympanic membrane: avoid application if the eardrum is ruptured.
  • Concurrent ototoxic drugs: monitor for additive ear toxicity.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Infectociprocort can interact with other medicines; awareness of these interactions helps maintain safety.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: increased risk of tendon rupture.
  • Ototoxic agents (e.g., aminoglycosides): additive ear toxicity.
  • Systemic corticosteroids: may enhance systemic steroid effects.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs: heightened risk of gastrointestinal irritation.
  • Warfarin: possible increase in INR and bleeding risk.

Frequently Asked Questions

Infectociprocort is a prescription ear preparation that combines ciprofloxacin, an antibacterial agent, with fluocinolone acetonide, a corticosteroid. It is indicated for the treatment of external otitis and other ear infections where both bacterial eradication and inflammation control are required.

Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication. By blocking these targets, the drug prevents bacterial cell division and leads to bacterial death, providing broad‑spectrum activity against the organisms that commonly cause ear infections.

The dosage and duration of Infectociprocort are determined by the prescribing clinician based on the severity of the infection, patient age, and ear condition. Patients should follow the exact instructions on the prescription label and consult their healthcare provider for any clarification.

Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare professional before using Infectociprocort.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Infectociprocort offers a dual mechanism: a fluoroquinolone antibiotic for bacterial eradication and a corticosteroid for inflammation reduction. This combination can be more convenient than using separate antibiotic and steroid drops, potentially improving adherence and providing faster symptom relief.

Store Infectociprocort at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

The preparation is applied directly into the affected ear(s) as a few drops, usually several times daily, according to the prescribing physician’s instructions. The patient should lie with the treated ear facing upward for a short period after instillation to allow adequate contact with the canal.

Serious risks include allergic reactions such as rash, swelling, or breathing difficulty, and ototoxicity that can lead to permanent hearing loss, especially when used with other ototoxic medications. Patients should seek immediate medical attention if they experience severe ear pain, dizziness, or signs of an allergic response.

Infectociprocort should be avoided in individuals with a known hypersensitivity to ciprofloxacin, fluocinolone acetonide, or any component of the formulation. It is also contraindicated in patients with a perforated tympanic membrane unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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