Product image of Infectoperm (Permethrin) supplied by GNH India

Infectoperm

Active Ingredient:
Permethrin
Origin:
EU

Infectoperm (Permethrin)

Permethrin, the active ingredient in Infectoperm, is a pyrethroid insecticide presented as a topical preparation for cutaneous use. It is employed to eradicate scabies mites and lice infestations on the skin of patients of all ages where appropriate.
GNH India supplies Infectoperm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim

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Indications & Clinical Uses

Infectoperm is a topical ectoparasiticide that acts on skin‑borne parasites.

  • Scabies: eliminates Sarcoptes scabiei mites, relieving itching and preventing spread.
  • Pediculosis (head lice, body lice): kills lice and nits, reducing infestation and transmission.
  • Other ectoparasitic skin infestations: treats less common mite or insect infestations such as chiggers or scabies‑like conditions.

How It Works

  • Permethrin interferes with voltage‑gated sodium channels on the neuronal membranes of ectoparasites. By prolonging the opening of these channels, it delays repolarization, causing persistent depolarization, paralysis, and ultimately death of the parasite without significant effect on mammalian nerve cells at therapeutic concentrations.

Side Effects

Topical application of permethrin can be associated with a range of skin reactions.

Common Side Effects

  • Mild skin irritation: redness or itching at the application site.
  • Burning sensation: transient warmth or tingling.
  • Dryness or flaking of the skin.
  • Localized rash or papules.
  • Pruritus after treatment.
  • Minor swelling.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) with swelling and difficulty breathing.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Severe dermatitis or bullous eruptions.
  • Systemic toxicity (rare) presenting as headache or dizziness.
  • Seizures (extremely rare) in susceptible individuals.
  • Persistent erythema or ulceration.

Precautions & Warnings

When using Infectoperm, consider the following safety measures.

  • Pregnancy: consult a healthcare professional; safety data are limited.
  • Breastfeeding: discuss risks and benefits with a physician.
  • Age restrictions: not recommended for infants younger than 2 months.
  • Skin integrity: avoid application on inflamed, broken, or ulcerated skin.
  • Concomitant topical agents: do not combine with other insecticides or irritants.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Permethrin may interact with other medications or substances applied to the skin.

Major Interactions (Avoid)

  • Neurotoxic agents (e.g., organophosphates): may increase neuroexcitation risk.
  • Other sodium‑channel blockers: additive paralytic effect on parasites and potential irritation.
  • Photosensitizing drugs: heightened skin sensitivity to sunlight.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask irritation signs.
  • Antihistamines: can reduce itching but do not affect efficacy.
  • Systemic insecticides: monitor for cumulative toxicity, especially in extensive applications.

Frequently Asked Questions

Infectoperm is a topical formulation containing permethrin that is used to treat scabies, head lice, body lice, and other ectoparasitic skin infestations. It works by killing the mites or lice that cause these conditions, helping to relieve itching and prevent further spread.

Permethrin blocks voltage‑gated sodium channels on the nerve cells of parasites. This blockage prolongs depolarization, leading to paralysis and death of the mite or louse while having minimal effect on human nerve cells at the concentrations used in topical therapy.

The exact dose and duration of treatment with Infectoperm are determined by the prescribing healthcare professional based on the specific indication, patient age, weight, and severity of infestation. The prescriber will provide detailed application instructions.

Safety data for permethrin use in pregnancy and lactation are limited. Women who are pregnant or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Infectoperm.

To request Infectoperm, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Infectoperm (permethrin) belongs to the pyrethroid class, which is widely regarded for its rapid knock‑down effect and low systemic absorption. Compared with older agents such as lindane, permethrin has a better safety profile and is less likely to cause neurotoxicity, making it a preferred first‑line option in many guidelines.

Infectoperm should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Infectoperm is applied topically to clean, dry skin. The prescribed amount is spread evenly over the affected area, left on for the duration specified by the prescriber, and then washed off as directed. Avoid contact with eyes, mouth, and mucous membranes.

Serious risks, although rare, include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and systemic toxicity that may present with neurological symptoms. Patients should seek immediate medical attention if they experience widespread rash, swelling, difficulty breathing, or neurological signs.

Infectoperm should not be used on infants younger than two months, on severely inflamed or broken skin, or in individuals with a known hypersensitivity to permethrin or any component of the formulation. Patients with a history of severe skin reactions should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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