Product image of Infectoscab (Permethrin) supplied by GNH India

Infectoscab

Active Ingredient:
Permethrin
Origin:
EU

Infectoscab (Permethrin)

Permethrin, the active ingredient in Infectoscab, is a pyrethroid insecticide presented as a topical formulation for skin application. It is employed to treat infestations caused by the Sarcoptes scabiei mite and Pediculus humanus lice, and is approved for use across the European Union in patients of all ages.

GNH India supplies Infectoscab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, with a focus on reliable quality, regulatory compliance, and timely delivery across global markets.

Manufacturer / TM Owner

Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim

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Indications & Clinical Uses

  • Infectoscab (permethrin) acts as a scabicide and pediculicide, targeting ectoparasites that infest the skin.
  • Scabies: eliminates Sarcoptes scabiei mites, relieving itching and preventing further transmission.
  • Pediculosis: eradicates head lice (Pediculus humanus capitis) and their eggs, reducing infestation.
  • Crusted scabies: controls severe mite burden in immunocompromised patients.

How It Works

  • Permethrin binds to voltage‑gated sodium channels on the neuronal membranes of mites and lice, prolonging channel opening and causing persistent depolarization. This results in paralysis and death of the parasite while human skin absorbs only minimal amounts, providing selective toxicity toward arthropods.

Side Effects

Topical permethrin may cause local skin reactions and, rarely, systemic effects.

Common Side Effects

  • Mild skin irritation: redness or itching at the application site.
  • Burning sensation: transient warmth where applied.
  • Pruritus: temporary itching after treatment.
  • Redness: mild erythema of the treated area.

Serious or Rare Side Effects

  • Severe allergic dermatitis: extensive rash, swelling, or hives.
  • Systemic neurotoxicity (rare): dizziness, headache, or seizures.
  • Secondary infection: bacterial infection of irritated skin.

Precautions & Warnings

  • When using Infectoscab, follow these safety considerations to minimize risk.
  • Application area: apply only to intact skin and avoid eyes, mouth, and mucous membranes.
  • Age restrictions: not recommended for infants under 2 months unless directed by a physician.
  • Concurrent skin conditions: avoid use on eczema, psoriasis, or extensive dermatitis without medical advice.
  • Pregnancy and lactation: consult healthcare provider before use as safety data are limited.
  • Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Permethrin topical can interact with certain substances and products; consider the following.

Major Interactions (Avoid)

  • Other topical insecticides or scabicides: concurrent use may increase skin irritation.
  • Phototoxic agents (e.g., psoralen): may enhance skin sensitivity to light.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may reduce efficacy of permethrin.
  • Occlusive dressings: can increase absorption and irritation.
  • Systemic medications that lower seizure threshold: monitor for rare neurotoxic signs.

Frequently Asked Questions

Infectoscab contains permethrin and is indicated for the treatment of scabies caused by Sarcoptes scabiei mites and pediculosis (head lice) caused by Pediculus humanus capitis. It is applied to the skin to eradicate the parasites and relieve associated symptoms.

Permethrin disrupts the function of voltage‑gated sodium channels in the nervous system of mites and lice. By keeping these channels open, it causes continuous nerve firing, leading to paralysis and death of the parasites while having limited absorption through human skin.

The dosage and duration of treatment with Infectoscab are determined by the prescribing healthcare professional based on the patient’s age, weight, and severity of infestation. Users should follow the specific instructions provided on the prescription label.

Safety data for topical permethrin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Infectoscab.

To request Infectoscab, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Infectoscab (permethrin) belongs to the pyrethroid class, offering a broad spectrum of activity against mites and lice with a favorable safety profile. Compared with older agents such as lindane, permethrin has lower neurotoxicity risk and is generally preferred in many guidelines for scabies and pediculosis.

Store Infectoscab at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and extreme heat to maintain its stability and efficacy.

Infectoscab is applied topically to clean, dry skin. The prescribed amount is spread evenly over the affected area, left on for the duration specified by the prescriber (usually several hours), and then washed off as directed.

Serious adverse reactions are rare but may include severe allergic dermatitis, systemic neurotoxicity such as seizures, and secondary bacterial infection of irritated skin. Any signs of an extensive rash, swelling, or neurological symptoms should prompt immediate medical attention.

Infectoscab should be avoided in individuals with known hypersensitivity to permethrin or other pyrethroids, in infants younger than two months unless specifically prescribed, and on severely damaged or inflamed skin without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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