Product image of Infectoscab (Permethrin) supplied by GNH India

Infectoscab

Active Ingredient:
Permethrin
Origin:
EU

Infectoscab (Permethrin)

Permethrin, the active ingredient in Infectoscab, is a pyrethroid presented as a topical formulation for skin application use. It treats scabies and lice infestations in patients of various ages. GNH India supplies Infectoscab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim

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Indications & Clinical Uses

  • Permethrin, a pyrethroid antiparasitic, is used to manage ectoparasitic skin infestations.
  • Scabies: eliminates the Sarcoptes scabiei mite and reduces associated itching.
  • Pediculosis: eradicates head lice and nits when indicated.

How It Works

  • Permethrin blocks voltage‑gated sodium channels in ectoparasites, prolonging neuronal depolarisation. This delayed repolarisation leads to paralysis and death of the mite or louse, thereby clearing the infestation from the skin.

Side Effects

Common Side Effects

  • Skin irritation: mild redness or itching at the application site.
  • Burning sensation: transient warmth or tingling.
  • Dryness: temporary flaking of treated skin.
  • Pruritus: occasional itching after treatment.
  • Erythema: mild redness.
  • Hyperpigmentation: rare temporary darkening of skin.

Serious or Rare Side Effects

  • Allergic reaction: swelling, hives, or difficulty breathing.
  • Severe dermatitis: intense rash or blistering.
  • Contact urticaria: localized swelling.
  • Systemic toxicity: rare, includes headache or dizziness.
  • Secondary infection: due to skin breakdown.
  • Persistent irritation: lasting beyond normal treatment period.

Precautions & Warnings

Before using Infectoscab, consider the following precautions:

  • Age restrictions: follow local guidelines for pediatric use.
  • Skin condition: avoid application on broken or inflamed skin.
  • Allergy history: do not use if known hypersensitivity to permethrin or other pyrethroids.
  • Concomitant medications: inform healthcare provider of any topical agents being used.
  • Pregnancy and lactation: consult a physician before use.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Permethrin may interact with other topical agents or systemic drugs.

Major Interactions (Avoid)

  • Concurrent use of other scabicidal or pediculicidal agents: may increase skin irritation.
  • Systemic neurotoxic drugs: potential additive neurotoxic effects.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may alter absorption and efficacy.
  • Antihistamines: may mask mild allergic reactions.
  • Other skin irritants: monitor for increased irritation or dermatitis.

Frequently Asked Questions

Infectoscab is indicated for the treatment of scabies, caused by Sarcoptes scabiei mites, and for pediculosis (lice infestation) when prescribed. It is applied to the skin to eradicate the parasites and relieve associated symptoms such as itching.

Permethrin interferes with the parasites' nervous system by blocking voltage‑gated sodium channels. This action prolongs neuronal depolarisation, leading to paralysis and death of the mite or louse, thereby clearing the infestation.

The specific dose and duration of treatment are determined by the prescribing healthcare professional based on the patient’s age, weight, and severity of infestation. Patients should follow the prescriber’s instructions exactly.

Safety data for permethrin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Infectoscab.

To place an order, submit an enquiry on the Infectoscab product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Infectoscab (permethrin) belongs to the pyrethroid class, which is generally well‑tolerated and effective after a single application. Alternative scabicides, such as benzyl benzoate or ivermectin, may require multiple doses or have different safety profiles. Choice of therapy depends on patient factors and physician preference.

Store Infectoscab at ambient temperature below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Infectoscab is applied topically to clean, dry skin, covering the entire affected area and a margin of surrounding skin. The medication is left on for the period specified by the prescriber, then washed off as directed.

Serious adverse reactions are rare but may include severe allergic responses such as swelling, hives, or difficulty breathing, as well as intense dermatitis or secondary skin infection. Any signs of a serious reaction should prompt immediate medical attention.

Infectoscab should be avoided in individuals with known hypersensitivity to permethrin or other pyrethroids, and it should not be applied to broken, inflamed, or infected skin without medical advice. Children under the age recommended by local guidelines should also not use the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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