Product image of Infectoscab (Permethrin) supplied by GNH India

Infectoscab

Active Ingredient:
Permethrin
Origin:
EU

Infectoscab (Permethrin)

Permethrin, the active ingredient in Infectoscab, is a pyrethroid insecticide presented as a topical preparation for skin application. It is used to treat infestations caused by scabies mites and lice in patients of all ages.
GNH India supplies Infectoscab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim

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Indications & Clinical Uses

Infectoscab is a topical scabicide and pediculicide that targets ectoparasitic infestations.

  • Scabies: eliminates Sarcoptes scabiei mites, relieving itching and preventing spread.
  • Pediculosis (lice): eradicates head and body lice, reducing infestation and transmission.

How It Works

  • Permethrin acts by binding to voltage‑gated sodium channels on the neuronal membranes of parasites, prolonging channel opening and disrupting normal nerve impulse transmission. This leads to paralysis and death of the ectoparasite, effectively clearing the infestation without significant systemic absorption in the host.

Side Effects

Adverse reactions are generally limited to the site of application and may vary in severity.

Common Side Effects

  • Skin irritation: mild redness or itching at the application site.
  • Burning sensation: transient warmth or tingling.
  • Pruritus: temporary increase in itching.
  • Erythema: localized redness.

Serious or Rare Side Effects

  • Allergic dermatitis: severe rash, swelling, or hives requiring medical attention.
  • Systemic toxicity: rare signs such as dizziness, headache, or seizures, especially with extensive skin coverage.

Precautions & Warnings

When using Infectoscab, follow these safety measures to minimize risks.

  • Application area: limit use to affected skin only and avoid mucous membranes.
  • Age restrictions: consult a healthcare professional before use in infants under two months.
  • Pre‑existing skin conditions: avoid application on eczematous or broken skin without medical advice.
  • Concomitant topical products: do not apply other creams or ointments over the treated area unless directed.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Permethrin may interact with other topical agents or systemic medications that affect the nervous system.

Major Interactions (Avoid)

  • Concurrent use of other neurotoxic insecticides: may increase risk of systemic toxicity.
  • Systemic antiepileptic drugs: potential additive neurotoxic effects.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask skin irritation signs.
  • Antihistamines: could alter perception of itching, affecting assessment of treatment response.
  • Other scabicidal or pediculicidal products: overlapping use may increase skin irritation.

Frequently Asked Questions

Infectoscab is indicated for the topical treatment of scabies caused by Sarcoptes scabiei mites and for pediculosis, which includes head and body lice infestations. It works by eliminating the parasites on the skin, relieving itching and preventing further spread.

Permethrin disrupts the function of voltage‑gated sodium channels in the nervous system of parasites. By keeping these channels open, it causes prolonged nerve depolarization, leading to paralysis and death of the scabies mites or lice without significant absorption into the human bloodstream.

The specific dose and duration of treatment with Infectoscab are determined by the prescribing healthcare professional based on the patient’s age, weight, and severity of infestation. Always follow the prescriber’s instructions and the product label.

Safety data for permethrin use in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing Infectoscab to pregnant or nursing individuals. Consultation with a specialist is recommended.

To request Infectoscab, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Infectoscab (permethrin) is a synthetic pyrethroid, offering a favorable safety profile and high efficacy compared with older agents such as benzyl benzoate or sulfur ointments. It requires a single application in many cases, whereas some alternatives need multiple doses, but choice of therapy should be guided by clinical judgment and patient factors.

Store Infectoscab at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and extreme heat to maintain product stability and potency.

Infectoscab is applied topically to clean, dry skin covering the entire affected area. The medication is left on the skin for the duration specified by the prescriber, then washed off as directed. Avoid contact with eyes, mouth and open wounds unless instructed otherwise.

Serious adverse reactions are rare but may include allergic dermatitis, severe skin rash, swelling, or systemic toxicity such as dizziness or seizures, especially if applied over large body surface areas. Immediate medical attention is required if any of these symptoms develop.

Infectoscab should be avoided in individuals with known hypersensitivity to permethrin or any component of the formulation. It is also contraindicated on extensive broken skin, mucous membranes, or in patients where a prescriber determines the risks outweigh the benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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