Product image of Infectoscab (Permethrin) supplied by GNH India

Infectoscab

Active Ingredient:
Permethrin
Origin:
EU

Infectoscab (Permethrin)

Permethrin, the active ingredient in Infectoscab, is a pyrethroid presented as a topical preparation for skin application. It treats scabies and pediculosis in patients of all ages.
GNH India supplies Infectoscab as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim

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Indications & Clinical Uses

Infectoscab is a topical antiparasitic that targets ectoparasite infestations of the skin.

  • Classic scabies: eliminates the Sarcoptes scabiei mite, relieving itching and preventing spread.
  • Crusted scabies: eradicates heavy mite loads in severe cases, reducing skin lesions.
  • Pediculosis (head lice): destroys lice and nits on the scalp, controlling infestation.

How It Works

  • Permethrin acts by binding to voltage‑gated sodium channels on the neuronal membranes of parasites. This blocks normal channel function, prolongs depolarization, leads to paralysis of the mite or louse, and ultimately results in death of the ectoparasite without significant systemic absorption in humans.

Side Effects

Infectoscab may cause local skin reactions, most of which are mild and self‑limiting.

Common Side Effects

  • Skin irritation: mild burning or stinging at the application site.
  • Redness: localized erythema.
  • Itching: transient pruritus.
  • Dryness: flaky or scaly skin.
  • Rash: mild maculopapular eruption.
  • Peeling: superficial desquamation.

Serious or Rare Side Effects

  • Allergic reaction: hives, swelling, or angioedema.
  • Severe dermatitis: intense redness, swelling, or blistering.
  • Stevens‑Johnson syndrome: rare mucocutaneous necrosis.
  • Systemic toxicity: rare, may present with neurological symptoms if large areas are applied on damaged skin.

Precautions & Warnings

Before using Infectoscab, consider the following safety measures.

  • Assess for hypersensitivity: avoid if the patient has known allergy to permethrin or other pyrethroids.
  • Apply to intact skin only: do not use on open wounds, eczema, or dermatitis.
  • Avoid ocular contact: keep product away from eyes and mucous membranes.
  • Use as directed: follow prescriber instructions regarding amount and duration.
  • Pediatric use: ensure proper dosing for children as advised by a healthcare professional.
  • Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Permethrin topical has limited systemic interactions, but certain co‑applications can affect safety.

Major Interactions (Avoid)

  • Concurrent use with other neurotoxic insecticides: may increase skin irritation.
  • Application over other scabicidal creams: can cause additive toxicity.

Moderate Interactions (Monitor Closely)

  • Use with topical corticosteroids: may mask early signs of irritation.
  • Extensive skin damage combined with permethrin: increased systemic absorption, monitor for neurological signs.
  • Co‑administration with photosensitizing agents: heightened risk of phototoxic reactions.

Frequently Asked Questions

Infectoscab is used to treat scabies, including classic and crusted forms, and pediculosis (head lice). The topical formulation targets the parasites on the skin, helping to relieve itching, eliminate the infestation, and prevent transmission to others.

Permethrin blocks voltage‑gated sodium channels in the nervous system of mites and lice. This disrupts normal nerve impulse transmission, causing prolonged depolarization, paralysis, and ultimately death of the parasite while remaining largely inactive on human skin.

The specific dose and duration of Infectoscab are determined by the prescribing healthcare professional based on the severity of the infestation, patient age, and body surface area. Patients should follow the prescriber’s instructions precisely.

Safety data for permethrin topical use in pregnancy and lactation are limited. Healthcare providers typically weigh potential benefits against risks. If prescribed, it should be applied only to the skin and avoided on the breast area to minimize exposure to the infant.

To order Infectoscab, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Infectoscab (permethrin) is a synthetic pyrethroid, offering a favorable safety profile and rapid parasite kill compared with older agents like benzyl benzoate or sulfur ointments. It requires a short treatment course and is generally well tolerated, making it a preferred first‑line option in many guidelines.

Store Infectoscab at temperatures below 25 °C in its original packaging. Keep the product away from moisture, direct sunlight, and sources of heat. Ensure the container is tightly closed to maintain product stability.

Infectoscab is applied topically to clean, dry skin. The prescribed amount is spread evenly over the affected area, usually from the neck down for scabies or on the scalp for lice, and left on for the duration indicated by the prescriber before washing off.

Serious risks, though rare, include severe allergic reactions such as hives, angioedema, or Stevens‑Johnson syndrome, and significant skin irritation if applied to broken skin or large body areas. Any signs of systemic toxicity, such as dizziness or seizures, require immediate medical attention.

Infectoscab should not be used by individuals with a known hypersensitivity to permethrin or other pyrethroids, on inflamed or broken skin, or in eyes and mucous membranes. It is also contraindicated in patients who have experienced severe reactions to previous scabicidal treatments.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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