Product image of Infilea (Clobetasol Propionate) supplied by GNH India

Infilea

Active Ingredient:
Clobetasol Propionate
Origin:
EU

Infilea (Clobetasol Propionate)

Clobetasol Propionate, the active ingredient in Infilea, is a topical corticosteroid presented as a topical formulation for skin application. It is used to treat inflammatory dermatoses such as psoriasis, eczema and other severe skin conditions in adults and children when prescribed by a healthcare professional.

GNH India supplies Infilea as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Egis Pharmaceuticals Plc

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Clobetasol Propionate acts on inflammatory skin disorders by reducing cytokine‑mediated inflammation and immune cell activity.

  • Psoriasis: diminishes scaling, erythema and plaque thickness.
  • Atopic dermatitis (eczema): relieves itching, redness and edema.
  • Lichen planus: reduces violaceous papules and ulceration.
  • Discoid lupus erythematosus: controls chronic cutaneous lesions and prevents new lesion formation.

How It Works

  • Clobetasol Propionate binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This interaction suppresses pro‑inflammatory cytokine production, inhibits leukocyte migration, and reduces fibroblast proliferation, resulting in potent anti‑inflammatory and immunosuppressive effects on the skin.

Side Effects

Clobetasol Propionate may cause local and systemic adverse reactions, most of which are dose‑ and duration‑dependent.

Common Side Effects

  • Burning or stinging at the application site.
  • Pruritus or mild itching.
  • Dryness or flaking of the skin.
  • Folliculitis or acneiform eruptions.
  • Mild skin erythema.

Serious or Rare Side Effects

  • Skin atrophy or thinning.
  • Telangiectasia (visible small blood vessels).
  • Hypopigmentation or depigmentation.
  • Secondary infection of treated area.
  • Systemic adrenal suppression with extensive use.

Precautions & Warnings

Clobetasol Propionate should be used with caution to minimize risks.

  • Limit application area: apply only to affected skin and avoid large surface areas.
  • Duration of therapy: restrict continuous use to the shortest period necessary, typically no longer than 2‑4 weeks.
  • Concomitant infections: avoid use on skin with bacterial, fungal or viral infections unless treated.
  • Pediatric use: exercise heightened caution in children due to increased systemic absorption.
  • Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Clobetasol Propionate can interact with other agents that affect corticosteroid metabolism or skin integrity.

Major Interactions (Avoid)

  • Concurrent systemic corticosteroids: may increase risk of systemic adrenal suppression.
  • Potent CYP3A4 inhibitors applied topically: may raise local drug concentration.

Moderate Interactions (Monitor Closely)

  • Antiviral or antifungal topical agents: may alter skin barrier and affect absorption.
  • Photosensitizing drugs (e.g., tetracyclines): increase risk of photosensitivity reactions.
  • Occlusive dressings: enhance percutaneous absorption, potentially leading to systemic effects.

Frequently Asked Questions

Infilea contains clobetasol propionate, a high‑potency topical corticosteroid that is prescribed for inflammatory skin disorders such as psoriasis, atopic dermatitis (eczema), lichen planus and discoid lupus erythematosus. It works by reducing redness, swelling, scaling and itching associated with these conditions.

Clobetasol propionate binds to glucocorticoid receptors inside skin cells, altering gene expression to suppress the production of inflammatory cytokines and chemokines. This reduces immune cell infiltration, edema and keratinocyte proliferation, providing a rapid anti‑inflammatory and immunosuppressive effect on the skin.

The specific dose and frequency of Infilea are determined by the prescribing clinician based on the severity of the skin condition, the area to be treated and patient factors. Patients should follow the healthcare professional’s instructions and not exceed the recommended amount.

Safety data for clobetasol propionate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To request Infilea, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Infilea (clobetasol propionate) is classified as a super‑potent (class I) corticosteroid, offering stronger anti‑inflammatory activity than mid‑potency agents such as betamethasone or mometasone. It is typically reserved for severe or resistant dermatoses where lower‑potency steroids have been ineffective.

Store Infilea at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and extreme heat to maintain its stability and potency.

Infilea is applied topically to clean, dry skin. A thin layer should be spread over the affected area, gently massaged in, and washed off after the prescribed period if instructed. Occlusive dressings should be avoided unless directed by a clinician.

Serious risks include skin atrophy, telangiectasia, hypopigmentation and, with extensive use, systemic adrenal suppression. Patients should report signs of severe thinning, bruising, unexplained fatigue or hormonal disturbances to their healthcare provider promptly.

Infilea should not be used on untreated bacterial, fungal or viral skin infections, on large surface areas for prolonged periods, or in individuals with known hypersensitivity to clobetasol propionate or any formulation excipients. Children under two years of age require special caution and medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.