Inflanor Plus (Ibuprofen, Paracetamol)

Inflanor Plus combines ibuprofen and paracetamol to address pain and fever pathways in the body.

• Pain: Relieves mild to moderate acute pain such as dental or postoperative discomfort.
• Fever: Reduces elevated body temperature associated with infections or inflammatory conditions.
• Inflammation: Decreases swelling and inflammation in conditions like arthritis or soft‑tissue injury.
• Headache: Alleviates tension‑type and mild migraine headaches.
• Musculoskeletal pain: Eases strain, sprain and back‑pain symptoms.

• Ibuprofen inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, lowering prostaglandin synthesis and thereby reducing inflammation, pain and fever. Paracetamol acts centrally to inhibit COX activity within the brain and modulates the endocannabinoid system, providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory action.

Inflanor Plus may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

• Nausea: Mild stomach upset or queasiness.
• Dyspepsia: Indigestion or heartburn.
• Headache: Transient mild headache.
• Dizziness: Light‑headed sensation.
• Rash: Minor skin irritation or redness.
• Elevated liver enzymes: Mild, often asymptomatic increase.

Serious or Rare Side Effects

• Gastrointestinal bleeding: Ulceration or bleeding in the stomach or intestines.
• Severe allergic reaction: Anaphylaxis, swelling of face or throat.
• Hepatotoxicity: Significant liver injury, jaundice.
• Renal impairment: Reduced kidney function, especially with dehydration.
• Stevens‑Johnson syndrome: Rare severe skin reaction.
• Hematologic abnormalities: Unusual bruising or bleeding.

Before using Inflanor Plus, consider the following safety measures.

• Assess renal function: Avoid use in patients with severe kidney disease.
• Evaluate hepatic status: Use cautiously in liver impairment.
• Review gastrointestinal risk: Patients with ulcer disease should use with food or under supervision.
• Monitor for cardiovascular risk: NSAIDs may increase blood pressure or clotting risk.
• Avoid in known hypersensitivity: Do not use if allergic to ibuprofen, paracetamol, or excipients.
• Store at ambient temperature: Keep below 25°C, in the original packaging, protected from moisture.

Inflanor Plus can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

• Anticoagulants (e.g., warfarin): Increased bleeding risk.
• Other NSAIDs or COX‑2 inhibitors: Heightened gastrointestinal toxicity.
• Hepatotoxic drugs (e.g., isoniazid, certain antituberculars): Potential liver injury.

Moderate Interactions (Monitor Closely)

• Antihypertensives (e.g., ACE inhibitors, diuretics): May reduce blood‑pressure control.
• Lithium: NSAIDs can raise lithium levels.
• Methotrexate: Reduced renal clearance may increase toxicity.
• SSRIs or SNRIs: Combined use may raise bleeding risk.