Product image of Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza virus vaccine, the active ingredient in Influvac, is a vaccine presented as a lyophilized powder for suspension for injection for intramuscular, subcutaneous use. It is used to prevent influenza infection caused by influenza A and B viruses in individuals at risk, such as adults and children.

GNH India supplies Influvac as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Viatris Healthcare Nv/Sa

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Indications & Clinical Uses

Influvac is a vaccine that targets influenza viruses to provide prophylactic protection.

  • Seasonal influenza: reduces the risk of illness caused by circulating influenza A and B strains during flu season.
  • Influenza A infection: prevents disease caused by influenza A viruses included in the vaccine composition.
  • Influenza B infection: prevents disease caused by influenza B viruses included in the vaccine composition.

How It Works

  • Influvac contains inactivated influenza virus antigens that stimulate the immune system to produce specific antibodies against the hemagglutinin and neuraminidase proteins of the included A and B strains. The antigenic exposure activates B‑cell and T‑cell responses, leading to immunological memory that can neutralize the virus upon subsequent exposure, thereby reducing infection risk. The lyophilized formulation is reconstituted before intramuscular or subcutaneous injection, ensuring antigen stability and optimal immune activation.

Side Effects

Common and serious adverse reactions have been reported following administration of Influvac.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness and swelling: localized erythema and edema.
  • Fever: low-grade temperature elevation within 24‑48 hours.
  • Headache: transient mild headache.
  • Myalgia: muscle aches lasting up to a few days.
  • Fatigue: general feeling of tiredness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder potentially triggered post‑vaccination.
  • Seizures: infrequent occurrence, especially in children with fever.
  • High fever: temperature above 39 °C persisting more than 48 hours.
  • Severe allergic reaction: urticaria, angioedema, or respiratory distress.
  • Thrombocytopenia: rare drop in platelet count.

Precautions & Warnings

Before administering Influvac, consider the following precautions and warnings.

  • Allergy assessment: verify no known hypersensitivity to egg proteins or any vaccine component.
  • Prior severe reaction: avoid in individuals who experienced anaphylaxis after a previous influenza vaccine.
  • Immunocompromised patients: vaccine may elicit a reduced immune response; assess benefit‑risk.
  • Age restriction: not indicated for children younger than 6 months.
  • Pregnancy and lactation: limited safety data; use only if potential benefit justifies risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac may interact with certain medical products or therapies; observe the following.

Major Interactions (Avoid)

  • Live attenuated vaccines: avoid simultaneous administration to prevent interference.
  • Immunoglobulin therapy: concurrent use may diminish vaccine‑induced immunity.
  • Antiviral agents (e.g., oseltamivir) taken within 48 hours: may reduce antibody response.

Moderate Interactions (Monitor Closely)

  • High‑dose corticosteroids: may lower immunogenicity, monitor protective effect.
  • Febrile illness at vaccination: postpone until recovery to reduce adverse events.
  • Co‑administration of other inactivated vaccines: generally safe but observe for additive local reactions.

Frequently Asked Questions

Influvac is an inactivated influenza virus vaccine indicated for the prophylactic prevention of influenza infection caused by the influenza A and B strains included in its formulation. It is administered to individuals at risk of seasonal flu, including adults and eligible children, to reduce the likelihood of illness, complications, and transmission.

The vaccine contains killed virus particles that present the hemagglutinin and neuraminidase antigens of the selected influenza strains. When injected, these antigens stimulate the immune system to generate specific antibodies and cellular immunity, creating immunological memory that can neutralize the live virus if the person is later exposed.

The prescribed dose of Influvac is determined by the treating healthcare professional. Typically, a single vial is reconstituted with the supplied diluent and administered as a single intramuscular or subcutaneous injection. Annual revaccination is recommended to maintain protection against circulating strains.

Safety data for Influvac in pregnant or lactating women are limited. The vaccine may be used during pregnancy only if the potential benefit to the mother outweighs any possible risk to the fetus. Breastfeeding mothers should consult their physician, as the vaccine is not known to be harmful but data are insufficient for a definitive recommendation.

To place an order, submit an enquiry on the Influvac product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After validation, the sales team provides pricing, availability, shipping details (including cold‑chain logistics where applicable) and assists with any required import documentation.

Influvac is an inactivated, split‑virus vaccine that includes specific A and B strains recommended for the current flu season. Compared with live‑attenuated nasal sprays, it is administered by injection and is suitable for a broader population, including immunocompromised individuals. Its safety profile is similar to other inactivated vaccines, but strain composition may differ from alternative brands depending on regional regulatory approvals.

Influvac must be stored refrigerated at 2 °C to 8 °C. Keep the vials in the original packaging, protect them from light, and avoid freezing or shaking the product. Once reconstituted, the suspension should be used immediately and discarded if not administered within the recommended time frame.

The vaccine is supplied as a lyophilized powder that is reconstituted with a sterile diluent immediately before use. The resulting suspension is injected intramuscularly, typically into the deltoid muscle, or subcutaneously according to the prescriber's instruction. Administration is performed by a qualified healthcare professional.

Serious adverse events, although rare, include anaphylaxis, Guillain‑Barré syndrome, severe allergic reactions, high‑grade fever, seizures, and thrombocytopenia. Patients should be observed for at least 15 minutes after injection, and any signs of severe reaction—such as difficulty breathing, swelling of the face or throat, or neurological symptoms—require immediate medical attention.

Influvac should not be given to individuals with a known severe allergy to any component of the vaccine, including egg proteins, or to those who have experienced anaphylaxis after a previous influenza vaccine. It is also contraindicated for children younger than six months of age. Persons with a history of Guillain‑Barré syndrome should discuss risks with their physician before vaccination.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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