Product image of Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza virus vaccine, the active ingredient in Influvac, is a vaccine presented as a vaccine formulation for intramuscular and subcutaneous use. It stimulates the immune system to produce antibodies against the included influenza A (Victoria) and influenza B (Austria) strains, providing protection against seasonal flu in children and adults.

GNH India supplies Influvac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides cold‑chain logistics to ensure product integrity.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

Influvac is indicated for immunization against influenza viruses, targeting the seasonal flu pathway.

  • Seasonal influenza: reduces the risk of laboratory‑confirmed influenza infection in the general population.
  • High‑risk groups (elderly, chronic disease patients): provides enhanced protection to lower rates of severe illness and hospitalization.
  • Travelers to regions with active flu activity: helps prevent infection during travel and reduces transmission risk.
  • Outbreak control in community settings: contributes to herd immunity and limits spread of influenza A and B strains.

How It Works

  • Influvac contains inactivated influenza virus antigens derived from the B/Austria/1359417/2021‑like and A/Victoria strains. After intramuscular or subcutaneous injection, the antigens are taken up by antigen‑presenting cells, which process and display them to T‑lymphocytes. This activates both humoral and cellular immune responses, leading to the production of strain‑specific neutralising antibodies that can block viral entry and replication upon exposure.

Side Effects

Common and serious adverse reactions may occur following administration of Influvac.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: localized erythema or edema lasting a few days.
  • Low‑grade fever: transient temperature rise within 24 hours.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder potentially triggered post‑vaccination.
  • Seizures: infrequent convulsive episodes, especially in children with fever.

Precautions & Warnings

Before administering Influvac, consider the following precautions to ensure safety and efficacy.

  • Allergy assessment: verify no known hypersensitivity to egg proteins or any vaccine component.
  • Acute illness: postpone vaccination if the recipient has a moderate or severe febrile illness.
  • Immunocompromised status: consult a healthcare professional for individuals with weakened immune systems.
  • Age restrictions: follow local guidelines for minimum and maximum age limits for vaccination.
  • Concomitant vaccines: separate administration from live vaccines by at least four weeks when possible.
  • Store at 2‑8 °C: keep refrigerated, protect from light, do not freeze or shake the vial.

Avoid Interactions

Vaccines may interact with certain medical conditions or therapies; the following interactions are recognized for Influvac.

Major Interactions (Avoid)

  • Severe egg allergy: contraindicates use due to vaccine residual egg proteins.
  • Recent receipt of blood products: may diminish immune response if given within three months.
  • Immunosuppressive therapy: inactivated influenza vaccine may have reduced efficacy; consult physician.

Moderate Interactions (Monitor Closely)

  • Antiviral medications (e.g., oseltamivir): may interfere with immune response if taken concurrently.
  • Chronic corticosteroid use: may lower antibody production, monitor serologic response.
  • Pregnancy: vaccine is generally considered safe, but discuss timing with obstetrician.

Frequently Asked Questions

Influvac is an inactivated influenza virus vaccine indicated for the prevention of seasonal influenza caused by influenza A and B viruses. It is administered to individuals to stimulate protective immunity and reduce the risk of flu infection, especially in high‑risk populations such as the elderly, young children, and those with chronic health conditions.

The vaccine contains purified, inactivated viral antigens from specific influenza strains. After injection, antigen‑presenting cells process these proteins and present them to T‑cells, initiating a coordinated immune response. This leads to the production of strain‑specific antibodies that can neutralise the virus, preventing it from infecting cells if the person is later exposed.

The exact dose and schedule are determined by the prescribing healthcare professional. Typically, a single intramuscular or subcutaneous dose is given each influenza season, with specific recommendations for age groups and prior vaccination history. The prescriber will decide the appropriate volume and site of administration.

Influvac is an inactivated vaccine and is generally considered safe for use during pregnancy and lactation when the benefits outweigh potential risks. Pregnant or breastfeeding individuals should discuss vaccination with their obstetrician or healthcare provider to ensure timing aligns with current clinical guidelines.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Influvac. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details—including cold‑chain logistics if needed—and necessary import documentation.

Influvac is an inactivated, split‑virus vaccine targeting the same influenza A (Victoria) and B (Austria) strains as many other seasonal vaccines. Compared with live‑attenuated nasal sprays, Influvac is administered by injection and is suitable for a broader range of age groups, including those with certain immunocompromising conditions. Efficacy and safety profiles are comparable to other licensed inactivated influenza vaccines.

Influvac must be stored refrigerated at 2 °C to 8 °C. It should be kept in its original packaging to protect from light, and must never be frozen or shaken. Prior to use, allow the vial to reach room temperature for a short period if required, and inspect for any discoloration or particulate matter before administration.

Influvac is given by a single intramuscular or subcutaneous injection, usually into the deltoid muscle of the upper arm or the anterolateral thigh in younger children. The injection is performed by a qualified healthcare professional using aseptic technique, and the site should be observed for any immediate reactions.

While rare, serious adverse events can include anaphylaxis, Guillain‑Barré syndrome, and seizures, particularly in children who develop a high fever. Recipients should be monitored for a short period after vaccination, and any signs of severe allergic reaction—such as difficulty breathing, swelling of the face or throat, or rapid pulse—require immediate medical attention.

Individuals with a known severe allergy to egg proteins or any component of the vaccine should avoid Influvac. Those who have experienced a previous severe reaction to any influenza vaccine should also be excluded. Additionally, persons with acute moderate or severe illness should defer vaccination until recovery.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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