Product image of Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza virus vaccine, the active ingredient in Influvac, is a vaccine presented as an injectable solution for intramuscular or subcutaneous use. It stimulates the immune system to produce antibodies against selected influenza virus strains, helping to prevent seasonal flu in individuals six months of age and older, and is recommended annually.

GNH India supplies Influvac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for global distribution.

Manufacturer / TM Owner

Viatris Healthcare Nv/Sa

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Indications & Clinical Uses

Influvac is an inactivated influenza vaccine that targets the influenza virus family to prevent seasonal flu, and it is administered annually to maintain immunity.

  • Seasonal influenza (all strains): reduces risk of infection and severity.
  • Influenza B (B/Austria/1359417/2021): induces protective antibodies against the B strain.
  • Influenza A (A/Vic): induces protective antibodies against the A/Vic strain.
  • High‑risk groups (elderly, chronic disease): lowers hospitalization and complications from flu.
  • Children (6 months–5 years): provides early protection against circulating influenza strains.
  • Pregnant women: helps protect mother and newborn from influenza complications.

How It Works

  • Influvac contains inactivated viral antigens from the selected influenza B and A strains. After intramuscular or subcutaneous injection, antigen‑presenting cells process these proteins, leading to activation of B‑lymphocytes and production of strain‑specific neutralising antibodies, while also stimulating T‑cell responses that together confer active immunity against the targeted influenza viruses.

Side Effects

Common side effects are generally mild and resolve without intervention.

Common Side Effects

  • Injection site pain, redness, or swelling.
  • Low‑grade fever (up to 38°C).
  • Headache.
  • Muscle aches.
  • Fatigue.
  • Nausea.

Serious or Rare Side Effects

  • Anaphylaxis or severe allergic reaction.
  • Guillain‑Barré syndrome.
  • High fever (>40°C).
  • Seizures.
  • Immune‑mediated thrombocytopenia.

Precautions & Warnings

Precautions should be observed to minimise risk and ensure optimal vaccine performance.

  • Allergy screening: avoid in persons with known hypersensitivity to any vaccine component.
  • Acute illness: postpone vaccination in individuals with moderate or severe feverish illness.
  • Pregnancy: consult a healthcare provider; use only if benefits outweigh potential risks.
  • Immunocompromised patients: vaccine may be less effective; consider alternative protective measures.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Vaccines may interact with other agents, affecting immune response or safety.

Major Interactions (Avoid)

  • Prior severe allergic reaction to any component of Influvac.
  • Concomitant administration with live attenuated vaccines without appropriate interval.
  • Use of investigational vaccines targeting the same strains.

Moderate Interactions (Monitor Closely)

  • Prophylactic antipyretics (e.g., acetaminophen) may blunt antibody response.
  • Ongoing immunosuppressive therapy may reduce vaccine efficacy.
  • Recent receipt of blood products could interfere with immune activation.
  • Seasonal antiviral medications may modestly affect immunogenicity.

Frequently Asked Questions

Influvac is an inactivated influenza vaccine indicated for the prevention of seasonal influenza infection. It is administered annually to individuals six months of age and older to stimulate protective immunity against the influenza virus strains included in the formulation.

The vaccine contains inactivated antigens from selected influenza B and A strains. After injection, the antigens are taken up by immune cells, prompting the body to produce strain‑specific antibodies and activate T‑cell responses, thereby establishing active immunity that can neutralise the targeted viruses.

The prescribed dose of Influvac is determined by a qualified healthcare professional based on the patient’s age, health status, and local immunization guidelines. The prescriber will select the appropriate volume and administration route for each individual.

Influvac may be administered to pregnant or breastfeeding individuals when the potential benefits outweigh any theoretical risks. Healthcare providers should evaluate each case, as the vaccine is generally considered safe but formal safety data are limited, and a risk‑benefit assessment is essential.

To place an order, submit an enquiry on the Influvac product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and necessary import documentation.

Influvac contains the specific B/Austria/1359417/2021‑like and A/Vic strains recommended for the current season, similar to other quadrivalent or trivalent vaccines. Differences may lie in the exact strain composition, manufacturing process, and regulatory approvals, but all aim to induce protective immunity against circulating influenza viruses.

Influvac must be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. The vaccine should be kept in its original packaging until use to maintain potency and stability throughout distribution.

Influvac is administered by a trained healthcare professional via intramuscular or subcutaneous injection, typically into the deltoid muscle of the upper arm. The injection site should be cleaned with an antiseptic, and the dose is delivered using a sterile needle and syringe.

The most serious risks include severe allergic reactions such as anaphylaxis, Guillain‑Barré syndrome, high fever, seizures, and immune‑mediated thrombocytopenia. Patients should be observed for a short period after vaccination and seek immediate medical attention if any severe symptoms develop.

Influvac should not be given to individuals with a known severe allergy to any component of the vaccine or to those who have experienced a serious reaction to a previous influenza vaccine. It should also be avoided in persons with active, uncontrolled acute illness until they recover.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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