Product image of Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26) and Influenza A/Vic, the active ingredient in Influvac, is a vaccine presented as an injectable solution for intramuscular or subcutaneous use. It is designed to prevent influenza infection caused by the included viral strains in individuals for whom annual vaccination is recommended, including adults, children, and high‑risk groups.

GNH India supplies Influvac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance across global markets.

Manufacturer / TM Owner

Viatris As

1
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Indications & Clinical Uses

  • Influvac is a vaccine that targets influenza viruses to provide seasonal protection.
  • Seasonal influenza: induces immunity against the specific B and A strains included, reducing the risk of infection.
  • High‑risk populations: lowers the likelihood of severe influenza complications in elderly, immunocompromised, and pregnant individuals.
  • Children: helps prevent influenza illness in pediatric patients, supporting community herd immunity.
  • Healthcare workers: provides protection to reduce transmission in clinical settings.

How It Works

  • Influvac contains inactivated split‑virion antigens from the selected influenza B/Austria/1359417/2021‑like strain and influenza A/Vic strain. After intramuscular or subcutaneous injection, these viral proteins are taken up by antigen‑presenting cells, prompting the adaptive immune system to generate strain‑specific antibodies against hemagglutinin and neuraminidase. The resulting humoral response confers active immunity that can neutralize the targeted influenza viruses upon subsequent exposure. This immunological priming typically persists for several months, aligning with the annual influenza vaccination schedule.

Side Effects

Influvac may be associated with a range of post‑vaccination reactions, most of which are mild and transient.

Common Side Effects

  • Injection site pain, redness or swelling.
  • Low‑grade fever.
  • Headache.
  • Muscle aches.
  • Fatigue.

Serious or Rare Side Effects

  • Anaphylaxis or severe allergic reaction.
  • Guillain‑Barré syndrome.
  • High fever.
  • Seizures (rare).

Precautions & Warnings

  • Prior to administering Influvac, healthcare providers should observe several precautionary measures to ensure safety.
  • Allergy assessment: Confirm no severe hypersensitivity to any vaccine component or previous influenza vaccine.
  • Acute illness evaluation: Defer vaccination in individuals with moderate or severe febrile illness until recovery.
  • Immunocompromised status: Recognize that immune response may be reduced; vaccinate but monitor efficacy.
  • Concurrent live vaccines: Avoid administering live attenuated vaccines simultaneously; schedule them separately.
  • Pregnancy consideration: Use only when the potential benefit outweighs any unknown risk; consult obstetric guidance.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac can interact with other medical products, influencing its effectiveness or safety profile.

Major Interactions (Avoid)

  • Severe allergy to vaccine components: contraindicated.
  • Concurrent administration of live attenuated vaccines: may reduce efficacy of either product.
  • High‑dose immunoglobulin therapy: can neutralize vaccine antigens and diminish immune response.

Moderate Interactions (Monitor Closely)

  • Antipyretic or analgesic use (e.g., acetaminophen, ibuprofen) around vaccination: may blunt antibody response; monitor.
  • Other inactivated vaccines given same day: generally safe but observe for additive local reactions.
  • Immunosuppressive drugs (e.g., corticosteroids, biologics): may lower vaccine-induced immunity; consider timing.

Frequently Asked Questions

Influvac is an inactivated influenza vaccine indicated for the prevention of seasonal influenza infection caused by the specific B/Austria/1359417/2021‑like and A/Vic virus strains. It is administered to individuals who are eligible for annual flu vaccination, including adults, children, and persons at higher risk of complications.

The vaccine contains split‑virion antigens from the selected influenza strains. After injection, these antigens are processed by antigen‑presenting cells, which stimulate the adaptive immune system to produce strain‑specific antibodies against hemagglutinin and neuraminidase. This antibody response provides active immunity that can neutralize the targeted viruses if exposure occurs.

The prescribed dose of Influvac is determined by the treating healthcare professional. Typically, a single intramuscular injection of the vaccine is given each influenza season, but the exact volume and administration schedule are set by the prescriber based on local guidelines and patient characteristics.

Safety data for Influvac in pregnancy and lactation are limited. The vaccine may be administered when the potential benefit to the mother outweighs any uncertain risk to the fetus. Healthcare providers should evaluate individual circumstances and discuss the decision with the patient. Breastfeeding is not a contraindication, but professional advice is recommended.

To place an order, submit an enquiry on the Influvac product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including cold‑chain handling) and any necessary import documentation.

Influvac is a split‑virion, inactivated vaccine that includes specific B and A strains. Compared with live‑attenuated or recombinant influenza vaccines, Influvac does not contain live virus and is suitable for a broader range of recipients, including those with certain immunocompromising conditions. Efficacy and safety profiles are comparable to other licensed inactivated influenza vaccines that target the same strains.

Influvac must be stored in a refrigerated environment at 2 °C to 8 °C. The vials should be kept in their original packaging to protect from light, should not be frozen, and must not be shaken vigorously. Maintaining the cold chain during transport and storage is essential to preserve vaccine potency.

Influvac is administered by a single intramuscular injection, usually into the deltoid muscle of the upper arm for adults or the anterolateral thigh for young children. The injection is performed by a qualified healthcare professional using aseptic technique. The dose is typically given once per influenza season.

The most serious adverse events reported with Influvac are severe allergic reactions, including anaphylaxis, and rare occurrences of Guillain‑Barré syndrome. These events require immediate medical attention. Patients should be observed for a short period after vaccination, and any signs of severe reaction should be reported to a healthcare provider promptly.

Influvac should not be given to individuals with a known severe allergy to any component of the vaccine or to those who have experienced a severe allergic reaction (e.g., anaphylaxis) after a previous dose of any influenza vaccine. Persons with a history of Guillain‑Barré syndrome following a prior influenza vaccination should also avoid this vaccine unless advised otherwise by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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