Product image of Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza Virus B/Austria/1359417/2021-like strain (B/Austria/1359417/2021, Bvr-26) and Influenza A/Vic, the active ingredients in Influvac, are inactivated influenza virus vaccines presented as a multi‑strain injectable for intramuscular or subcutaneous use. They stimulate immunity to prevent seasonal influenza caused by the included B and A strains in adults and children.

GNH India supplies Influvac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory support for global distribution. Its logistics network ensures timely delivery in compliance with cold‑chain requirements.

Manufacturer / TM Owner

Viatris Healthcare Lda.

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Indications & Clinical Uses

Influvac is used to prevent influenza infection by targeting the seasonal influenza virus strains included in the vaccine.

  • Seasonal influenza (B/Austria/1359417/2021-like strain): Provides immunity that reduces the risk of illness caused by the matched influenza B strain.
  • Seasonal influenza (Influenza A/Vic strain): Induces protective antibodies against the A/Vic virus, decreasing infection rates.
  • General influenza prevention: Helps lower overall community transmission of the circulating influenza viruses covered by the formulation.

How It Works

  • Influvac contains inactivated whole virus particles from the specified influenza B and A strains. After intramuscular or subcutaneous injection, the viral antigens are taken up by antigen‑presenting cells, which display hemagglutinin and neuraminidase proteins to T‑cells. This triggers B‑cell activation and the production of strain‑specific antibodies, establishing active immunity that neutralizes the targeted influenza viruses upon exposure.

Side Effects

Like all vaccines, Influvac may be associated with local and systemic reactions.

Common Side Effects

  • Injection site pain: mild to moderate soreness at the site of administration.
  • Redness or swelling: transient erythema or edema around the injection.
  • Low‑grade fever: temperature rise up to 38 °C within 24 hours.
  • Headache: mild headache lasting a day or two.
  • Myalgia: muscle aches commonly reported after vaccination.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder reported post‑vaccination.
  • Seizures: infrequent occurrence, especially in children with fever.
  • Thrombocytopenia: low platelet count observed in isolated cases.

Precautions & Warnings

Before administering Influvac, healthcare professionals should consider the following precautions.

  • Allergy assessment: avoid use in individuals with severe hypersensitivity to any vaccine component.
  • Previous reaction: postpone vaccination if the patient experienced a serious reaction to a prior influenza vaccine.
  • Acute illness: defer vaccination until recovery from moderate or severe febrile illness.
  • Immunocompromised patients: vaccine may be less immunogenic; assess benefit‑risk individually.
  • Storage: Store at 2‑8 °C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac may interact with other agents; relevant interactions are categorized below.

Major Interactions (Avoid)

  • Live attenuated vaccines: avoid simultaneous administration; separate by at least 4 weeks to prevent interference.
  • Immunoglobulin therapy: concurrent use may reduce vaccine efficacy; schedule at least 2 weeks apart.

Moderate Interactions (Monitor Closely)

  • Antipyretics (e.g., acetaminophen, ibuprofen): may blunt antibody response if given prophylactically; use only for symptomatic relief.
  • Immunosuppressive drugs (e.g., corticosteroids, biologics): may diminish immune response; monitor seroconversion.
  • Egg‑based vaccine production: individuals with severe egg allergy should be evaluated, although most modern formulations are low‑egg.

Frequently Asked Questions

Influvac is an inactivated influenza vaccine indicated for the prevention of influenza infection caused by the specific influenza B/Austria/1359417/2021-like strain and the influenza A/Vic strain. It is administered to individuals at risk of seasonal flu to reduce the likelihood of illness, hospitalization, and complications associated with these viral strains.

The vaccine contains killed virus particles that present hemagglutinin and neuraminidase antigens to the immune system. After injection, antigen‑presenting cells process these proteins, activating T‑cells and prompting B‑cells to produce strain‑specific antibodies. These antibodies can neutralize the corresponding live viruses if the person is later exposed.

The dose of Influvac is determined by the prescribing healthcare professional based on the patient’s age, health status, and local immunization guidelines. The vaccine is typically given as a single intramuscular or subcutaneous injection per season, but the exact volume and schedule are set by the prescriber.

Data on the use of inactivated influenza vaccines like Influvac during pregnancy are limited, but such vaccines are generally considered safe when the potential benefits outweigh any theoretical risks. Breastfeeding mothers should consult their healthcare provider to decide whether vaccination is appropriate for them and their infant.

To order Influvac, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details—including cold‑chain logistics—and any necessary import documentation.

Influvac is an inactivated, trivalent formulation targeting the B/Austria/1359417/2021-like and A/Vic strains, whereas many modern vaccines are quadrivalent and include additional A/H3N2 or B/Victoria lineages. Inactivated vaccines are suitable for immunocompromised patients and do not carry a risk of live virus replication, but the breadth of protection may differ from broader‑spectrum quadrivalent options.

Influvac must be stored refrigerated at 2 °C to 8 °C. It should be kept in its original packaging, protected from light, and must not be frozen or shaken. Maintaining the cold chain during transport and storage is essential to preserve vaccine potency.

Influvac is administered by a qualified healthcare professional via intramuscular or subcutaneous injection, usually into the deltoid muscle of the upper arm. The injection site should be cleaned with an appropriate antiseptic, and the dose is given as a single shot per vaccination season unless otherwise directed by a clinician.

The most serious adverse events reported with influenza vaccines include severe allergic reactions (anaphylaxis) and, rarely, neurological conditions such as Guillain‑Barré syndrome. These events are uncommon, but patients should be observed for a short period after vaccination and seek immediate medical care if symptoms of a severe reaction develop.

Influvac should not be given to individuals with a known severe allergy to any component of the vaccine or to those who have experienced a serious reaction to a previous dose of the same vaccine. Persons with acute moderate or severe illness should defer vaccination until recovery. Consultation with a healthcare provider is essential for anyone with underlying health concerns.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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