Product image of Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), the active ingredient in Influvac, is a vaccine presented as a sterile injectable formulation for intramuscular or subcutaneous use. It is intended to induce immunity against the included influenza A and B virus strains, helping to prevent influenza infection in eligible individuals.

GNH India supplies Influvac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for global distribution.

Manufacturer / TM Owner

Viatris Ab

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Indications & Clinical Uses

Influvac is an influenza vaccine used to prevent infection caused by circulating influenza viruses.

  • Seasonal influenza: provides protection against matched influenza A and B strains during the flu season.
  • Influenza B (Austria strain): induces immunity specifically against the B/Austria/1359417/2021‑like virus.
  • Influenza A (Victoria strain): induces immunity against the A/Vic strain included in the formulation.

How It Works

  • Influvac contains inactivated influenza virus antigens that are recognized by the immune system as foreign. Upon intramuscular or subcutaneous injection, antigen‑presenting cells process the viral proteins and present them to T‑lymphocytes, stimulating a coordinated B‑cell response that produces strain‑specific antibodies. These antibodies neutralize the corresponding influenza viruses, reducing the likelihood of infection and disease severity.

Side Effects

Common and serious adverse reactions may occur following administration of Influvac.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: localized erythema or edema.
  • Low‑grade fever: temperature elevation up to 38 °C.
  • Headache: transient mild headache.
  • Myalgia: muscle aches lasting 1–2 days.
  • Fatigue: temporary feeling of tiredness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder with muscle weakness.
  • Seizures: infrequent convulsive episodes.
  • Severe local reaction: extensive swelling or necrosis at injection site.
  • High‑grade fever: temperature above 39 °C persisting >48 h.
  • Thrombotic events: very rare clotting complications.

Precautions & Warnings

Before administering Influvac, healthcare professionals should observe several safety considerations.

  • Allergy assessment: avoid vaccination in persons with a known severe allergy to any vaccine component.
  • Pregnancy counseling: discuss potential benefits and risks with pregnant individuals; vaccination may be considered when indicated.
  • Immunocompromised patients: evaluate risk‑benefit as response may be reduced.
  • Acute febrile illness: defer vaccination until the individual has recovered.
  • Age eligibility: administer only to the age groups approved by regulatory authorities.
  • Store at 2‑8 °C: keep refrigerated, protect from light, do not freeze or shake the vial.

Avoid Interactions

Influvac may interact with other medical products; clinicians should review patient medication histories.

Major Interactions (Avoid)

  • Live vaccines: do not co‑administer with other live attenuated vaccines within four weeks.
  • Severe allergic reaction to a previous influenza vaccine: avoid repeat dosing.

Moderate Interactions (Monitor Closely)

  • Immunosuppressive therapy: may diminish vaccine‑induced immunity, monitor antibody response.
  • Antipyretic medications: can mask post‑vaccination fever, use judiciously.
  • Antiviral drugs (e.g., oseltamivir): may interfere with immune response if given concurrently.
  • Egg allergy: monitor for mild reactions, though most modern vaccines have reduced egg protein.

Frequently Asked Questions

Influvac is an inactivated influenza vaccine indicated for the prevention of seasonal influenza infection. It targets the influenza A (Victoria) and influenza B (Austria) strains included in the formulation, helping to reduce the risk of illness in individuals who receive the vaccine as part of routine immunisation programmes.

The vaccine contains inactivated viral antigens from the selected influenza strains. After injection, these antigens are taken up by antigen‑presenting cells, which trigger T‑cell activation and stimulate B‑cells to produce strain‑specific antibodies. The resulting antibodies can neutralise the corresponding influenza viruses, providing protective immunity.

The prescribed dose of Influvac is determined by a qualified healthcare professional. Typically, a single intramuscular (or subcutaneous) injection is administered each influenza season, but the exact volume and administration schedule are set by the prescriber based on local guidelines and patient factors.

Influvac may be administered to pregnant or breastfeeding individuals when the potential benefits outweigh any theoretical risks. Healthcare providers should evaluate each case individually, discuss the safety profile, and follow national recommendations regarding influenza vaccination during pregnancy and lactation.

To place an order, submit an enquiry on the Influvac product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed) and any required import documentation.

Influvac is an inactivated, split‑virus vaccine that includes specific A (Victoria) and B (Austria) strains. Compared with live‑attenuated or recombinant influenza vaccines, it does not contain live virus and is suitable for a broader range of patients, including those with certain immunocompromising conditions. Efficacy and safety are comparable to other licensed seasonal influenza vaccines.

Influvac must be stored at 2 °C to 8 °C (refrigerated). Keep the vials in their original packaging, protect them from light, and avoid freezing or shaking. Prior to use, inspect the product for any discoloration or particulate matter and discard if the integrity is compromised.

Influvac is given by a single intramuscular or subcutaneous injection, usually into the deltoid muscle of the upper arm. The administration should be performed by a qualified healthcare professional using aseptic technique, following the dosage and site‑selection guidelines provided in the product’s prescribing information.

Serious adverse events, although rare, can include anaphylaxis, Guillain‑Barré syndrome, severe local reactions, high‑grade fever lasting more than 48 hours, and very rare thrombotic complications. Patients should be observed for a short period after vaccination and instructed to seek immediate medical attention if they experience symptoms such as difficulty breathing, swelling of the face or throat, or sudden weakness.

Influvac should be avoided in individuals with a documented severe allergy to any component of the vaccine or to a previous dose of an influenza vaccine. It is also contraindicated in persons who have experienced a severe allergic reaction (e.g., anaphylaxis) after a prior influenza immunisation. Clinicians should assess each patient’s medical history before vaccination.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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