Product image of Influvac S (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac S

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac S (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic, the active ingredient in Influvac S, is an influenza vaccine presented as an injectable formulation for intramuscular or subcutaneous use. It is intended to prevent influenza infection caused by influenza A and B viruses in individuals aged six months and older.

GNH India supplies Influvac S as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides cold‑chain logistics to ensure product integrity during global distribution.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

  • Influvac S is an influenza vaccine used to prevent seasonal influenza caused by influenza A and B viruses.
  • Seasonal influenza: reduces the risk of laboratory‑confirmed influenza infection in the general population.
  • High‑risk groups (e.g., elderly, young children, chronic disease patients): provides enhanced protection against severe disease and complications.
  • Pandemic preparedness: contributes to herd immunity and supports public health strategies during influenza outbreaks.

How It Works

  • Influvac S contains inactivated antigens from the B/Austria/2021‑like strain and the A/Vic strain. After intramuscular or subcutaneous injection, antigen‑presenting cells process these proteins and present them to T‑lymphocytes, initiating a humoral immune response that generates strain‑specific neutralising antibodies, thereby protecting the host from subsequent exposure to the matching influenza viruses.

Side Effects

Like other injectable influenza vaccines, Influvac S may be associated with local and systemic reactions.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: transient erythema or edema around the injection area.
  • Low‑grade fever: temperature rise up to 38 °C within 24 hours.
  • Headache: mild headache lasting a day or two.
  • Muscle aches: transient myalgia.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare demyelinating neuropathy reported post‑vaccination.
  • Seizures: uncommon febrile seizures in young children.
  • Thrombotic events: very rare clotting disorders.

Precautions & Warnings

Before administering Influvac S, healthcare professionals should consider the following precautions.

  • Allergy assessment: avoid use in individuals with known hypersensitivity to any vaccine component.
  • Fever or acute illness: defer vaccination until recovery.
  • Previous vaccine reaction: evaluate risk if a severe reaction occurred after a prior influenza vaccine.
  • Pregnancy and lactation: discuss benefits and risks with the prescriber; data are limited.
  • Storage at 2‑8 °C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac S may interact with other agents, although vaccine‑specific drug interactions are uncommon.

Major Interactions (Avoid)

  • Live attenuated vaccines: avoid co‑administration within 4 weeks to prevent interference with immune response.
  • Immunoglobulin therapy: postpone vaccination for at least 3 months after receipt of immune globulin.
  • High‑dose immunosuppressive therapy: avoid during intense corticosteroid treatment as response may be reduced.

Moderate Interactions (Monitor Closely)

  • Antipyretics (acetaminophen, ibuprofen): may reduce antibody response if taken prophylactically; use for symptom relief only after vaccination.
  • Antiviral drugs (oseltamivir): generally safe but monitor for any alteration in vaccine efficacy.

Frequently Asked Questions

Influvac S is a preventive vaccine indicated for the seasonal protection against influenza infection caused by both influenza A and influenza B viruses. It is administered to individuals six months of age and older to reduce the likelihood of contracting the flu and to lessen disease severity in case of infection.

The vaccine contains inactivated viral antigens from the B/Austria/2021‑like strain and the A/Vic strain. When injected, these antigens are captured by antigen‑presenting cells, which trigger a T‑cell‑dependent immune response. This leads to the production of specific neutralising antibodies that can block the virus from infecting cells, providing protective immunity.

The dosing regimen for Influvac S is determined by the prescribing healthcare professional. Typically, a single intramuscular or subcutaneous dose is given each influenza season, with the exact volume and administration site selected according to local guidelines and patient age.

Safety data for Influvac S in pregnant or lactating women are limited. The vaccine should only be used during pregnancy or breastfeeding when the potential benefits outweigh any theoretical risks. Healthcare providers should discuss individual circumstances with the patient before administration.

To order Influvac S, submit an enquiry on the product page at https://gnhindia.com/product/influvac-s, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping options and the necessary import documentation.

Influvac S contains the same WHO‑recommended strains for the 2021‑2022 season as other licensed quadrivalent vaccines, but its specific B‑strain (Austria/2021) and A/Vic component may differ from some competitors. Efficacy, safety profile and storage requirements are comparable, while formulation differences can affect antigen content and manufacturing processes.

Influvac S must be stored refrigerated at 2 °C to 8 °C. It should be kept in its original packaging, protected from light, and must never be frozen or shaken. During transport, a validated cold‑chain system is required to maintain temperature stability.

Influvac S is administered by a qualified healthcare professional via a single intramuscular or subcutaneous injection, usually into the deltoid muscle of the upper arm. The injection site should be cleaned with an appropriate antiseptic, and the vaccine should be used immediately after removal from refrigeration.

The most serious adverse events reported with Influvac S include anaphylaxis, a severe allergic reaction that requires immediate emergency treatment, and Guillain‑Barré syndrome, a rare neurological disorder that may develop weeks after vaccination. Patients should be observed for at least 15 minutes after injection to detect any acute reactions.

Influvac S should not be given to individuals with a documented severe allergy to any component of the vaccine, including the viral antigens or excipients. It is also contraindicated in persons who have experienced a life‑threatening reaction to a previous influenza vaccine. Consultation with a healthcare provider is essential for anyone with unclear medical history.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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