Product image of Influvac Sub-Unit (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac Sub-Unit

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac Sub-Unit (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic, the active ingredient in Influvac Sub-Unit, is a vaccine presented as a subunit formulation for intramuscular or subcutaneous use. It is intended to prevent influenza infection caused by the included influenza A and B virus strains in eligible populations.

GNH India supplies Influvac Sub-Unit as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

Influvac Sub-Unit is a subunit influenza vaccine indicated for prevention of influenza caused by influenza A and B viruses.

  • Seasonal influenza: provides immunity against circulating influenza A (including A/Vic) and B (including B/Austria/1359417/2021) strains.
  • High‑risk groups: reduces the risk of influenza‑related complications in the elderly, immunocompromised individuals, and patients with chronic medical conditions.
  • Pandemic preparedness: contributes to population immunity during influenza seasons when the vaccine strains match circulating viruses.

How It Works

  • Influvac Sub-Unit contains purified hemagglutinin subunit proteins from the selected influenza A and B strains. After intramuscular or subcutaneous injection, these antigens are taken up by antigen‑presenting cells, stimulating B‑cell and T‑cell responses that lead to the production of strain‑specific neutralising antibodies, thereby providing protective immunity against infection.

Side Effects

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: localized erythema or edema.
  • Low‑grade fever: transient temperature rise.
  • Headache: mild headache within 24‑48 hours.
  • Myalgia: muscle aches.
  • Fatigue: temporary tiredness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder.
  • High fever: temperature >39°C persisting beyond 48 hours.
  • Seizures: especially in children with febrile reactions.
  • Myocarditis or pericarditis: inflammation of heart muscle or sac.
  • Severe local reaction: necrosis or abscess at injection site.

Precautions & Warnings

Precautions should be observed before administering Influvac Sub-Unit.

  • Age restriction: not recommended for infants younger than 6 months.
  • Allergy: avoid if the patient has a severe allergy to egg proteins or any vaccine component.
  • Immunocompromised patients: may exhibit reduced immune response; assess benefit‑risk.
  • Acute illness: defer vaccination in individuals with moderate or severe acute febrile illness.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Potential drug and vaccine interactions should be considered.

Major Interactions (Avoid)

  • Live attenuated vaccines: avoid co‑administration within 4 weeks.
  • Immunoglobulin therapy: may neutralise vaccine antigens and diminish response.
  • Antiviral agents started before vaccination (e.g., oseltamivir): can interfere with immunogenicity.

Moderate Interactions (Monitor Closely)

  • Inactivated vaccines given concurrently: monitor for additive local reactions.
  • Immunosuppressive drugs (e.g., high‑dose steroids): may reduce antibody production; timing may need adjustment.
  • Antipyretics taken prophylactically: could blunt the desired immune response; use only if needed.

Frequently Asked Questions

Influvac Sub-Unit is a subunit influenza vaccine used to prevent infection caused by influenza A and B viruses. It is administered to individuals at risk of seasonal flu, including adults, elderly persons, and those with chronic health conditions, to reduce the likelihood of illness and related complications.

The vaccine contains purified hemagglutinin proteins from selected influenza A and B strains. After injection, these proteins are recognized by the immune system, prompting B‑cells and T‑cells to generate specific antibodies. The resulting antibodies neutralise the virus if the person is later exposed, providing protective immunity.

The dosage and schedule of Influvac Sub-Unit are determined by the prescribing healthcare professional based on age, health status, and local immunisation guidelines. Typically, a single dose is given annually, but the exact volume and route are specified by the prescriber.

Safety data for use during pregnancy or lactation are limited. Healthcare providers should evaluate the potential benefits and risks before vaccinating pregnant or breastfeeding individuals. In many regions, inactivated influenza vaccines are considered acceptable when the benefits of preventing flu outweigh theoretical risks.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed), and necessary import documentation.

Influvac Sub-Unit is a subunit vaccine that contains only purified viral surface proteins, offering a well‑tolerated safety profile compared with whole‑virus or live‑attenuated vaccines. It targets the same influenza strains as other seasonal vaccines but may have fewer reactogenic components, making it suitable for individuals with specific sensitivities.

The vaccine must be stored refrigerated between 2 °C and 8 °C. It should be kept in the original packaging to protect from light, must not be frozen, and should not be shaken. Proper cold‑chain management is essential to maintain potency until administration.

Influvac Sub-Unit is administered by a qualified healthcare professional via intramuscular or subcutaneous injection, typically into the deltoid muscle of the upper arm. The injection site is cleaned with an antiseptic, and the dose is delivered using a sterile needle and syringe.

Serious adverse events, although rare, include anaphylactic reactions, Guillain‑Barré syndrome, high fever, seizures, and myocarditis. Patients should be observed for a short period after vaccination and instructed to seek immediate medical care if they experience symptoms such as difficulty breathing, swelling of the face or throat, or severe neurological signs.

Individuals with a known severe allergy to any component of the vaccine, including egg protein, should avoid it. Infants younger than 6 months are not eligible. Persons with a history of severe allergic reaction to a previous influenza vaccine dose should consult their clinician before receiving Influvac Sub-Unit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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