Product image of Influvac Sub-Unit (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac Sub-Unit

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac Sub-Unit (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26) and Influenza A/Vic, the active ingredients in Influvac Sub-Unit, are subunit vaccine components presented as a subunit vaccine for intramuscular or subcutaneous use. They stimulate immunity to prevent influenza infection caused by influenza A and B viruses in children and adults.

GNH India supplies Influvac Sub-Unit as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing and regulatory support for global immunization programmes.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

Influvac Sub-Unit is indicated for active immunization against seasonal influenza caused by influenza A and B viruses.

  • Seasonal influenza: reduces the risk of laboratory‑confirmed influenza infection in the general population.
  • High‑risk groups (elderly, chronic disease patients): provides added protection to lower rates of severe disease and hospitalization.
  • Pandemic preparedness: contributes to herd immunity and supports public health response to emerging influenza strains.

How It Works

  • Influvac Sub-Unit contains purified hemagglutinin subunits from selected influenza A (Victoria lineage) and B (Austria lineage) viruses. After intramuscular or subcutaneous injection, the antigenic proteins are taken up by antigen‑presenting cells, processed, and displayed to T‑cells, prompting B‑cell activation and production of strain‑specific neutralizing antibodies. This adaptive immune response confers active protection against subsequent exposure to the matched influenza viruses.

Side Effects

Influvac Sub-Unit may be associated with local and systemic reactions following administration.

Common Side Effects

  • Pain at the injection site: mild to moderate discomfort.
  • Redness and swelling: transient local inflammation.
  • Low‑grade fever: usually resolves within 24‑48 hours.
  • Headache: mild and self‑limiting.
  • Myalgia: muscle aches that improve spontaneously.
  • Fatigue: temporary feeling of tiredness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder reported post‑vaccination.
  • Severe allergic reaction: including angioedema or bronchospasm.
  • Seizures: uncommon, especially in children with pre‑existing neurological conditions.
  • High‑grade fever: persistent fever above 39 °C.
  • Extensive skin rash: widespread erythema or urticaria.

Precautions & Warnings

Prior to vaccination, consider the following precautions to ensure safe use of Influvac Sub-Unit.

  • Contraindication: known severe allergy to any vaccine component.
  • Pregnancy: safety not established; weigh benefits against potential risks.
  • Immunocompromised patients: may have reduced immune response.
  • Acute illness: defer vaccination until recovery from moderate or severe febrile illness.
  • Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac Sub-Unit may interact with other medical products or therapies.

Major Interactions (Avoid)

  • Concurrent administration of another influenza vaccine: avoid duplicate dosing.
  • Live attenuated vaccines given within 4 weeks: may interfere with immune response.

Moderate Interactions (Monitor Closely)

  • Immunosuppressive therapy (e.g., corticosteroids, chemotherapy): may diminish antibody response.
  • Prophylactic antipyretics: may reduce vaccine‑induced fever but not efficacy.
  • Blood products administered within 48 hours: may affect immune activation.

Frequently Asked Questions

Influvac Sub-Unit is a subunit influenza vaccine indicated for active immunization against seasonal influenza caused by influenza A (Victoria lineage) and influenza B (Austria lineage) viruses. It is used to reduce the risk of infection, severe disease, and hospitalization in the general population and high‑risk groups.

The vaccine contains purified hemagglutinin subunits from selected influenza strains. After injection, these antigens are processed by antigen‑presenting cells, activating T‑cells and prompting B‑cells to produce strain‑specific neutralizing antibodies. The resulting adaptive immune response provides protection against future exposure to the matched influenza viruses.

The dosage and schedule of Influvac Sub-Unit are determined by the prescribing healthcare professional based on age, health status, and local immunization guidelines. The prescriber will select the appropriate volume and route (intramuscular or subcutaneous) for each individual patient.

Safety data for Influvac Sub-Unit in pregnancy are limited, and the product is classified as pregnancy category unknown. Healthcare providers should assess the potential benefits and risks before vaccinating pregnant or breastfeeding individuals. When benefits outweigh potential risks, vaccination may be considered.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. After verification of trade or institutional credentials, the sales team will respond with pricing, availability, shipping details (including cold‑chain handling), and any required import documentation.

Influvac Sub-Unit is a subunit vaccine that uses purified hemagglutinin proteins, offering a well‑tolerated safety profile compared with whole‑virus or live‑attenuated vaccines. It does not contain live virus, reducing the risk of replication‑related adverse events, and is suitable for individuals with certain contraindications to live vaccines.

The vaccine must be stored refrigerated at 2 °C to 8 °C. It should be kept in the original packaging, protected from light, and must not be frozen or shaken. Maintaining the cold chain during transport and storage is essential to preserve vaccine potency.

Influvac Sub-Unit is administered by a trained healthcare professional via intramuscular or subcutaneous injection, typically into the deltoid muscle of the upper arm. The injection site should be cleaned with an appropriate antiseptic, and the dose is given as a single vial per vaccination episode.

Serious but rare risks include anaphylaxis, Guillain‑Barré syndrome, severe allergic reactions, seizures, high‑grade fever, and extensive skin rash. Patients should be observed for a short period after vaccination, and any signs of severe reaction should be treated promptly and reported to medical authorities.

Individuals with a known severe allergy to any component of the vaccine, including egg protein if present, should not receive Influvac Sub-Unit. Those who have experienced a previous severe reaction to a similar influenza subunit vaccine should also avoid it. Consultation with a healthcare provider is essential for anyone with contraindications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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