Product image of Influvac Sub-Unit (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac Sub-Unit

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac Sub-Unit (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza Virus B/Austria/1359417/2021-like strain and Influenza A/Vic, the active ingredients in Influvac Sub-Unit, are subunit vaccine components presented as an injectable vaccine for intramuscular or subcutaneous use. They induce immunity to protect against seasonal influenza A and B infections in adults and eligible children.
GNH India supplies Influvac Sub-Unit as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

Influvac Sub-Unit is a subunit influenza vaccine used to prevent infection by influenza viruses.

  • Influenza A (including A/Vic) infection: reduces the risk of illness, hospitalization and complications.
  • Influenza B (B/Austria/1359417/2021‑like) infection: lowers the chance of acquiring disease and its severe outcomes.
  • Seasonal influenza: provides prophylactic protection for at‑risk populations such as the elderly, healthcare workers and individuals with chronic conditions.

How It Works

  • The vaccine contains purified viral surface proteins from influenza A (A/Vic) and influenza B (B/Austria/1359417/2021‑like) strains. After intramuscular or subcutaneous injection, these subunit antigens are taken up by antigen‑presenting cells, which display them to T‑cells, stimulating B‑cell production of strain‑specific antibodies. The resulting humoral response equips the immune system to neutralise the corresponding influenza viruses upon exposure.

Side Effects

Common Side Effects

  • Injection site pain or tenderness.
  • Redness or swelling at the injection site.
  • Low‑grade fever.
  • Headache.
  • Muscle aches (myalgia).
  • Fatigue.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Guillain‑Barré syndrome.
  • Seizures.
  • High fever (≥39°C).
  • Thrombocytopenia.
  • Severe local inflammation or necrosis.

Precautions & Warnings

Before administering Influvac Sub-Unit, consider the following precautions.

  • Contraindication: severe allergy to any vaccine component.
  • Caution: history of Guillain‑Barré syndrome after a previous influenza vaccine.
  • Pregnancy: limited data; use only if potential benefits outweigh risks.
  • Immunocompromised patients: may exhibit reduced immune response.
  • Age restriction: not recommended for children under 6 months.
  • Store at 2‑8 °C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Vaccination may be influenced by other therapies.

Major Interactions (Avoid)

  • Concurrent administration of blood products containing antibodies: may diminish vaccine effectiveness.
  • Use of high‑dose immunoglobulin therapy: can interfere with immune response.

Moderate Interactions (Monitor Closely)

  • Immunosuppressive drugs (e.g., corticosteroids, chemotherapy): may reduce antibody production.
  • Antipyretic or analgesic medication taken prophylactically: may mask mild post‑vaccination fever.
  • Live vaccines given within 4 weeks: could affect immune response to either product.

Frequently Asked Questions

Influvac Sub-Unit is a subunit influenza vaccine indicated for the prevention of seasonal influenza caused by influenza A (including the A/Vic strain) and influenza B (B/Austria/1359417/2021‑like) viruses. It is administered to individuals at risk of flu complications, such as the elderly, healthcare workers, and people with chronic medical conditions.

The vaccine contains purified surface proteins from the targeted influenza strains. After injection, these antigens are processed by immune cells, which trigger a specific antibody response. The generated antibodies recognize and neutralise the corresponding influenza viruses, providing protective immunity if the person is later exposed to the virus.

The dose and schedule of Influvac Sub-Unit are determined by the prescribing healthcare professional based on age, health status, and local immunisation guidelines. The product is supplied as a single‑use injectable preparation, and the prescriber will specify the exact volume and route for each patient.

Safety data for Influvac Sub-Unit in pregnancy are limited. It may be administered during pregnancy only if the expected benefit to the mother outweighs any potential risk to the fetus. Breastfeeding is not a contraindication, but mothers should discuss vaccination with their healthcare provider to make an informed decision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and any necessary import documentation.

Influvac Sub-Unit is a subunit vaccine that uses purified viral proteins rather than whole‑virus particles or live attenuated virus. This design can result in a lower reactogenicity profile compared with some inactivated or live‑attenuated vaccines, while still providing effective protection against the included A and B strains.

The vaccine must be stored refrigerated at 2‑8 °C. It should be kept in its original packaging to protect from light, must not be frozen, and should not be shaken. Prior to administration, inspect the vial for any particulate matter or discoloration and use within the recommended time after reconstitution, if applicable.

Influvac Sub-Unit is given by a single intramuscular or subcutaneous injection, typically into the deltoid muscle of the upper arm. The exact route, site and volume are determined by the prescribing clinician, following local immunisation protocols and the product’s prescribing information.

Serious adverse events, although rare, can include anaphylaxis, Guillain‑Barré syndrome, severe allergic reactions, high fever, seizures, and thrombocytopenia. Patients should be observed for a short period after vaccination and instructed to seek immediate medical attention if they experience symptoms such as difficulty breathing, swelling of the face or throat, or neurological changes.

Individuals with a known severe allergy to any component of the vaccine, including egg protein if present, should not receive Influvac Sub-Unit. It is also contraindicated for persons who have experienced a previous severe reaction to an influenza subunit vaccine. Children younger than six months of age are not eligible for this vaccine.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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