Product image of Influvac Sub-Unit (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac Sub-Unit

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac Sub-Unit (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza virus vaccine (subunit), the active ingredient in Influvac Sub-Unit, is a vaccine presented as a subunit formulation for intramuscular/subcutaneous use. It induces immunity to prevent influenza infection caused by influenza A and B viruses in the general population, including high‑risk groups.

GNH India supplies Influvac Sub-Unit as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides cold‑chain logistics for global distribution.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

Influvac Sub-Unit is used to prevent influenza caused by viruses of the A and B families.

  • Seasonal influenza: reduces the risk of infection and associated complications in the general population.
  • Elderly and immunocompromised patients: provides protective immunity to lower severe disease rates.
  • Healthcare workers: helps limit transmission of influenza in clinical settings.

How It Works

  • The subunit vaccine contains purified hemagglutinin and neuraminidase proteins from influenza A and B strains. After intramuscular or subcutaneous injection, these antigens are taken up by antigen‑presenting cells, stimulating B‑cell production of strain‑specific antibodies and activating T‑cell help, thereby establishing active immunity against future exposure to the matched influenza viruses.

Side Effects

Like other injectable vaccines, Influvac Sub-Unit may be associated with local and systemic reactions.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the site of administration.
  • Redness or swelling: transient erythema or edema around the injection area.
  • Low‑grade fever: temperature rise up to 38°C within 24‑48 hours.
  • Headache or muscle aches: transient discomfort lasting a day or two.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder that may follow vaccination.
  • Seizures or high fever: uncommon but potentially serious systemic events.
  • Hypotension: sudden drop in blood pressure after injection.
  • Severe local reaction: extensive swelling or necrosis at the injection site.

Precautions & Warnings

Prior to vaccination, certain safety considerations should be observed.

  • Assess allergy history: avoid in individuals with known severe allergy to any vaccine component.
  • Delay vaccination: postpone if moderate or severe acute illness is present.
  • Monitor after injection: observe for at least 15 minutes for signs of anaphylaxis.
  • Use with caution in immunosuppressed patients: vaccine may elicit reduced immune response.
  • Do not freeze: keep refrigerated.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac Sub-Unit may interact with other medical products; awareness of key interactions helps ensure safety.

Major Interactions (Avoid)

  • Live attenuated vaccines: concurrent administration may interfere with immune response.
  • Immunosuppressive therapy (e.g., high‑dose steroids, chemotherapy): may diminish vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Antipyretics (acetaminophen, ibuprofen): may mask post‑vaccination fever.
  • Antihistamines: may reduce local reaction but do not prevent systemic response.
  • Blood products given within 48 hours: may affect antibody development.

Frequently Asked Questions

Influvac Sub-Unit is a subunit influenza vaccine indicated for the prevention of influenza infection caused by influenza A and B viruses. It is administered to individuals, including those at higher risk of complications such as the elderly, immunocompromised patients, and healthcare workers, to reduce the incidence and severity of seasonal flu.

The vaccine contains purified surface proteins—primarily hemagglutinin and neuraminidase—from selected influenza A and B strains. After injection, these proteins are recognized by the immune system, prompting antigen‑presenting cells to activate B‑cells and T‑cells. This leads to the production of strain‑specific antibodies that neutralize the virus, providing active immunity against future exposure.

The dosing regimen for Influvac Sub-Unit is determined by the prescribing healthcare professional based on age, health status, and local immunization guidelines. Typically, a single intramuscular or subcutaneous injection is given each influenza season, but the exact volume and schedule are set by the prescriber.

Data on the use of subunit influenza vaccines during pregnancy are limited, but they are generally considered when the potential benefits outweigh any theoretical risks. Breastfeeding mothers may also receive the vaccine. Healthcare providers should evaluate individual circumstances and discuss any concerns with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. The sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details—including cold‑chain handling where required—and import documentation.

Influvac Sub-Unit is a subunit vaccine that contains only purified viral proteins, whereas split‑virus or whole‑virus vaccines include additional viral components. Subunit vaccines often have a lower reactogenicity profile, resulting in fewer local reactions, but they may require adjuvants to enhance immune response. Efficacy against matched strains is comparable when administered according to guidelines.

The vaccine must be stored at 2‑8 °C in a refrigerator, protected from light, and must never be frozen or shaken. It should be kept in the original packaging until use to maintain potency. During transport, a validated cold‑chain system is required to keep the product within the recommended temperature range.

Influvac Sub-Unit is administered by a qualified healthcare professional via intramuscular or subcutaneous injection, usually into the deltoid muscle of the upper arm. The injection site should be cleaned with an antiseptic, and the dose is delivered using a sterile needle and syringe following standard aseptic technique.

The most serious adverse events include anaphylactic reactions, which require immediate medical intervention, and rare neurological conditions such as Guillain‑Barré syndrome. Patients should be observed for at least 15 minutes post‑vaccination and instructed to seek urgent care if they experience difficulty breathing, swelling of the face or throat, or rapidly progressing weakness.

Individuals with a known severe allergy to any component of the vaccine, including egg protein if present, should not receive Influvac Sub-Unit. Those who have experienced a previous severe reaction to a similar influenza subunit vaccine should also avoid it. Pregnant or breastfeeding women should consult their healthcare provider to weigh benefits against potential risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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