Product image of Influvac Tetra (B/Phuket/3073/2013-Like Virus (B/Phuket/3073/2013, Wild Type), Influenza Virus B/Austria/1359417/202) supplied by GNH India

Influvac Tetra

Active Ingredient:
B/Phuket/3073/2013-Like Virus (B/Phuket/3073/2013, Wild Type), Influenza Virus B/Austria/1359417/202
Origin:
EU

Influvac Tetra (B/Phuket/3073/2013-Like Virus (B/Phuket/3073/2013, Wild Type), Influenza Virus B/Austria/1359417/202)

B/Phuket/3073/2013-Like Virus (B/Phuket/3073/2013, Wild Type), Influenza Virus B/Austria/1359417/202, the active ingredient in Influvac Tetra, is an inactivated influenza virus vaccine presented as an injectable solution for intramuscular or subcutaneous use. It is intended to prevent influenza infection in individuals at risk, including adults and children.

GNH India supplies Influvac Tetra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for import and distribution, ensuring reliable supply chains across regions.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

  • Influvac Tetra is an inactivated influenza vaccine used to prevent seasonal influenza infection.
  • Seasonal influenza: provides immunity against the influenza A(H1N1), A(H3N2), B/Victoria and B/Yamagata lineages included in the vaccine.
  • High‑risk populations: reduces the likelihood of influenza‑related complications in elderly, immunocompromised or chronic‑disease patients.
  • Pediatric use: offers protection for children aged 6 months and older as part of routine immunisation programmes.

How It Works

  • Influvac Tetra contains purified, inactivated whole‑virus particles from four influenza strains. After intramuscular or subcutaneous injection, the viral antigens are taken up by antigen‑presenting cells, which process and display them to helper T cells. This triggers B‑cell activation and the production of strain‑specific neutralising antibodies, establishing active immunity that can neutralise matching influenza viruses upon exposure. Memory B cells generated by this response enable rapid antibody production on subsequent viral encounter.

Side Effects

Influvac Tetra, like other injectable vaccines, may be associated with local and systemic reactions.

Common Side Effects

  • Pain, redness or swelling at the injection site.
  • Low‑grade fever (up to 38°C).
  • Headache or mild fatigue.
  • Myalgia (muscle aches).

Serious or Rare Side Effects

  • Anaphylaxis or severe allergic reaction.
  • Guillain‑Barré syndrome.
  • Seizures or high fever (>40°C).
  • Prolonged bleeding at the injection site.
  • Severe systemic reactions requiring medical attention.

Precautions & Warnings

  • Before administering Influvac Tetra, consider the following precautions.
  • Screen for severe allergy: verify no known hypersensitivity to any vaccine component.
  • Delay vaccination: postpone in individuals with acute moderate or severe illness.
  • Observe after injection: monitor for at least 15 minutes for immediate reactions.
  • Avoid in known anaphylaxis: do not administer to persons with prior severe allergic reaction to influenza vaccines.
  • Pregnancy and lactation: assess risk‑benefit; limited data available.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac Tetra may interact with other medicines or vaccines.

Major Interactions (Avoid)

  • Live vaccines: avoid co‑administration with live attenuated vaccines within 4 weeks.
  • Immunoglobulins: do not give within 3 months as they may reduce vaccine efficacy.
  • Antiviral drugs: concurrent use of neuraminidase inhibitors may interfere with immune response.

Moderate Interactions (Monitor Closely)

  • Immunosuppressive therapy: monitor antibody response, may need revaccination.
  • Febrile illness: may increase risk of systemic reactions; consider timing.
  • Allergic medications: antihistamines may mask early allergic signs; observe closely.

Frequently Asked Questions

Influvac Tetra is an inactivated quadrivalent influenza vaccine indicated for the prevention of seasonal influenza infection in individuals six months of age and older. It is administered to reduce the risk of flu‑related illness, complications, and transmission within the community.

The vaccine contains purified, inactivated whole‑virus particles from four influenza strains. After injection, the viral antigens are processed by the immune system, prompting B‑cell activation and the generation of strain‑specific neutralising antibodies. This active immunity enables the body to recognise and neutralise matching influenza viruses upon future exposure.

The prescribed dose of Influvac Tetra is determined by a qualified healthcare professional. Typically, a single intramuscular or subcutaneous injection is given each influenza season, but the exact volume and administration schedule are set by the prescriber based on age, health status and local immunisation guidelines.

Data on the use of Influvac Tetra in pregnant or lactating individuals are limited. Healthcare providers should evaluate the potential benefits against any theoretical risks. In many regions, inactivated influenza vaccines are considered acceptable during pregnancy when the benefit of protecting the mother and fetus outweighs uncertainties.

To order Influvac Tetra, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including cold‑chain logistics) and any necessary import documentation.

Influvac Tetra is a quadrivalent, inactivated vaccine that covers two influenza A subtypes and both B lineages, offering broader protection than trivalent formulations. Unlike live‑attenuated nasal sprays, it is administered by injection and is suitable for a wider range of age groups, including immunocompromised patients, due to its non‑replicating nature.

The vaccine must be stored refrigerated at 2‑8 °C. It should be kept in the original packaging to protect from light, must not be frozen, and should not be shaken. Prior to administration, allow the vial to reach room temperature for a short period if required by local practice.

Influvac Tetra is supplied as a sterile injectable solution. It is given by a single intramuscular or subcutaneous injection, usually into the deltoid muscle of the upper arm for adults or the anterolateral thigh for infants and young children, following aseptic technique and standard vaccination procedures.

The most serious adverse events reported are severe allergic reactions such as anaphylaxis, Guillain‑Barré syndrome, and high‑grade fever or seizures. These events are rare but require immediate medical attention. Recipients should be observed for at least 15 minutes after injection to detect any early signs of a serious reaction.

Influvac Tetra should not be administered to individuals with a known severe allergy to any component of the vaccine or to those who have experienced a previous anaphylactic reaction to an influenza vaccine. It is also contraindicated in persons with active, moderate or severe acute illness until they have recovered.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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