Product image of Influvac Tetra (B/Phuket/3073/2013-Like Virus (B/Phuket/3073/2013, Wild Type), Influenza Virus B/Austria/1359417/202) supplied by GNH India

Influvac Tetra

Active Ingredient:
B/Phuket/3073/2013-Like Virus (B/Phuket/3073/2013, Wild Type), Influenza Virus B/Austria/1359417/202
Origin:
EU

Influvac Tetra (B/Phuket/3073/2013-Like Virus (B/Phuket/3073/2013, Wild Type), Influenza Virus B/Austria/1359417/202)

B/Phuket/3073/2013‑Like Virus (B/Phuket/3073/2013, Wild Type) and Influenza Virus B/Austria/1359417/202, the active ingredients in Influvac Tetra, are influenza virus vaccine components presented as an injectable formulation for intramuscular or subcutaneous use. They stimulate immune protection against seasonal influenza strains in children and adults.

GNH India supplies Influvac Tetra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

Influvac Tetra is indicated for the prevention of influenza infection, targeting the seasonal influenza virus family.

  • Seasonal influenza: reduces the incidence of flu illness in eligible populations.
  • Influenza B/Yamagata lineage (B/Phuket): provides immune protection against the B/Phuket strain.
  • Influenza B/Victoria lineage (B/Austria): provides immune protection against the B/Austria strain.

How It Works

  • Influvac Tetra contains inactivated influenza virus antigens that are taken up by antigen‑presenting cells after intramuscular or subcutaneous injection. The antigens are processed and displayed to T cells, prompting B‑cell activation and the production of strain‑specific antibodies. These antibodies neutralize circulating influenza viruses, thereby preventing infection or reducing disease severity.

Side Effects

Administration of Influvac Tetra may be associated with local and systemic reactions.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: transient erythema or edema around the injection area.
  • Fever: low‑grade temperature elevation within 24‑48 hours.
  • Headache: mild headache occurring shortly after vaccination.
  • Myalgia: muscle aches commonly reported in the days following injection.
  • Fatigue: temporary feeling of tiredness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurological disorder potentially linked to vaccination.
  • Severe allergic reaction: urticaria, angioedema, or respiratory distress.
  • Seizures: uncommon neurologic events post‑vaccination.
  • High fever: temperature >40°C persisting beyond 48 hours.
  • Thrombocytopenia: rare drop in platelet count.

Precautions & Warnings

Before administering Influvac Tetra, consider the following precautions.

  • Allergy screening: verify no severe allergy to egg protein or vaccine components.
  • Acute illness: postpone vaccination in individuals with moderate or severe febrile illness.
  • Immunocompromised patients: assess risk‑benefit as response may be reduced.
  • Concomitant vaccines: separate administration of live vaccines by at least 4 weeks.
  • Pregnancy and lactation: discuss potential benefits and limited data with the prescriber.
  • Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac Tetra may interact with other therapies; monitor accordingly.

Major Interactions (Avoid)

  • Live attenuated vaccines: concurrent use can interfere with immune response.
  • Immunoglobulin therapy: may diminish vaccine‑induced immunity.

Moderate Interactions (Monitor Closely)

  • Antipyretics (e.g., acetaminophen): may mask fever, affecting post‑vaccination monitoring.
  • Antiviral medications (e.g., oseltamivir): could alter immune response if started shortly before vaccination.
  • Immunosuppressive drugs: may reduce vaccine efficacy, requiring timing adjustments.
  • Corticosteroids (systemic): monitor for attenuated antibody production.

Frequently Asked Questions

Influvac Tetra is a quadrivalent influenza vaccine used to protect against seasonal flu caused by influenza A and two B lineages. It is administered to children and adults to reduce the risk of infection, severe disease, and complications associated with influenza.

The vaccine contains inactivated virus particles from the B/Phuket and B/Austria strains. After injection, the immune system recognizes these antigens, activates T‑cells, and stimulates B‑cells to produce specific antibodies. These antibodies neutralize the corresponding influenza viruses if the person is later exposed.

The dose of Influvac Tetra is determined by the prescribing healthcare professional based on age, health status, and local immunization guidelines. Typically, a single intramuscular injection is given each flu season, but the exact regimen should be confirmed by the prescriber.

Data on Influvac Tetra use in pregnancy and lactation are limited. Health authorities generally consider inactivated influenza vaccines acceptable when the benefits outweigh potential risks. Pregnant or breastfeeding individuals should discuss vaccination with their obstetrician or primary care provider.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details, and necessary import documentation.

Influvac Tetra is a quadrivalent vaccine covering two A strains and both B lineages, similar to other modern flu vaccines. Compared with trivalent formulations, it offers broader protection against circulating B viruses. Its safety profile and administration route are comparable to other injectable influenza vaccines.

The vaccine must be stored refrigerated at 2‑8 °C. Keep it in the original packaging, protect it from light, and avoid freezing or shaking. Before use, inspect the vial for any discoloration or particulate matter and discard if the appearance is abnormal.

Influvac Tetra is administered by a trained healthcare professional via intramuscular or subcutaneous injection, usually into the deltoid muscle of the upper arm. The injection site should be cleaned with an antiseptic, and the patient should be observed for a short period after vaccination.

The most serious adverse events are rare but include anaphylaxis, Guillain‑Barré syndrome, and severe allergic reactions. Immediate medical attention is required if symptoms such as difficulty breathing, swelling of the face or throat, or rapid onset of weakness occur after vaccination.

Individuals with a known severe allergy to any component of the vaccine, including egg protein, should not receive it. Those who have experienced a previous severe reaction to an influenza vaccine should also avoid it. Consultation with a healthcare provider is essential for anyone with uncertain contraindications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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