Product image of Influvac Tri (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic) supplied by GNH India

Influvac Tri

Active Ingredient:
Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic
Origin:
EU

Influvac Tri (Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26), Influenza A/Vic)

Influenza Virus B/Austria/1359417/2021-Like Strain (B/Austria/1359417/2021, Bvr-26) and Influenza A/Vic, the active ingredients in Influvac Tri, are trivalent influenza vaccines presented as a solution for injection for intramuscular or subcutaneous use. They are intended to induce immunity against seasonal influenza A (including H1N1, H3N2) and influenza B viruses in adults and children.

GNH India supplies Influvac Tri as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality and regulatory compliance.

Manufacturer / TM Owner

Viatris Austria Gmbh

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Indications & Clinical Uses

Influvac Tri is indicated for the prevention of influenza caused by influenza A and B viruses.

  • Influenza A (H1N1, H3N2): reduces risk of infection and severe disease.
  • Influenza B (Victoria lineage): provides protection against circulating B strains.
  • Seasonal influenza outbreaks: offers prophylactic immunity for the flu season.

How It Works

  • The vaccine contains inactivated hemagglutinin and neuraminidase antigens from the selected influenza A (H1N1, H3N2) and influenza B (Victoria) strains. After intramuscular or subcutaneous injection, these antigens are taken up by antigen‑presenting cells, stimulating B‑cell production of strain‑specific antibodies and activating T‑cell responses, thereby establishing active immunity that neutralizes the virus upon exposure.

Side Effects

Influvac Tri may be associated with local and systemic reactions following injection.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the injection site.
  • Redness or swelling: localized erythema or edema.
  • Fever: transient low‑grade temperature rise.
  • Headache: mild headache within 24 hours.
  • Myalgia: muscle aches lasting up to two days.
  • Fatigue: general tiredness after vaccination.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Guillain‑Barré syndrome: rare neurologic disorder with muscle weakness.
  • Seizures: infrequent convulsive events post‑vaccination.
  • High fever: temperature > 39 °C persisting beyond 48 hours.
  • Severe allergic reaction: urticaria, angioedema, or respiratory distress.
  • Neurologic events: encephalitis or meningitis symptoms.

Precautions & Warnings

Before administering Influvac Tri, consider the following precautions to ensure safe use.

  • Allergy to egg proteins: avoid vaccination in individuals with severe egg allergy.
  • History of severe vaccine reaction: contraindicated in persons with prior anaphylaxis to influenza vaccines.
  • Acute illness: postpone vaccination until recovery from moderate or severe febrile illness.
  • Immunocompromised patients: vaccine may elicit reduced immune response; assess benefit‑risk.
  • Pregnancy and breastfeeding: discuss with healthcare provider; vaccine generally considered safe but use based on clinical judgment.
  • Store at 2‑8 °C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Influvac Tri can interact with certain medical products; observe the following guidance.

Major Interactions (Avoid)

  • Live attenuated vaccines: do not administer concurrently with live vaccines such as nasal flu spray.
  • Immunoglobulin or blood products: avoid within 3 months of vaccination as they may neutralize the antigen.
  • High‑dose corticosteroids: avoid within 2 weeks before or after vaccination due to suppressed immune response.

Moderate Interactions (Monitor Closely)

  • Antiviral agents (e.g., oseltamivir): may reduce vaccine‑induced antibody response; monitor efficacy.
  • Immunosuppressive therapy: may diminish immunogenicity; assess protective antibody levels.
  • Allergic conditions: monitor for enhanced local or systemic reactions in patients with severe atopy.

Frequently Asked Questions

Influvac Tri is a trivalent influenza vaccine indicated to prevent seasonal influenza caused by influenza A (including H1N1 and H3N2 subtypes) and influenza B viruses. It is administered before the flu season to reduce the risk of infection and related complications in eligible individuals.

The vaccine contains inactivated hemagglutinin and neuraminidase proteins from selected influenza strains. After injection, these antigens are processed by immune cells, prompting the body to produce strain‑specific antibodies and activate T‑cell responses. This prepares the immune system to recognize and neutralize the actual virus if exposure occurs.

The dosage of Influvac Tri is determined by the prescribing healthcare professional. Typically, a single dose is given each influenza season, administered intramuscularly or subcutaneously according to local guidelines and the patient’s age and health status.

Influvac Tri may be administered to pregnant or breastfeeding individuals after a risk‑benefit assessment by a qualified clinician. While inactivated influenza vaccines are generally considered safe, the decision should be based on the woman's health, gestational age, and potential exposure to influenza.

To order Influvac Tri, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details, and necessary import documentation.

Influvac Tri is a trivalent, inactivated vaccine covering two influenza A subtypes and one influenza B lineage. Compared with quadrivalent formulations, it protects against one B strain instead of two. Its safety profile and administration route are similar to other injectable influenza vaccines, but the specific strain composition may differ each season.

Influvac Tri must be stored refrigerated at 2 °C to 8 °C. Keep the vials in the original packaging, protect them from light, and avoid freezing or shaking. During transport, maintain the cold chain to preserve vaccine potency.

The vaccine is supplied as a sterile solution for injection. A qualified healthcare professional administers a single dose intramuscularly, typically into the deltoid muscle, or subcutaneously if intramuscular injection is not feasible. The injection site should be cleaned with an appropriate antiseptic before administration.

Serious adverse events are rare but may include anaphylaxis, Guillain‑Barré syndrome, high‑grade fever lasting more than 48 hours, and severe neurologic reactions such as encephalitis. Any signs of severe allergic reaction, difficulty breathing, or rapidly progressing weakness should prompt immediate medical evaluation.

Individuals with a known severe allergy to any component of the vaccine, including egg proteins, or those who have experienced a previous anaphylactic reaction to an influenza vaccine should not receive Influvac Tri. Persons with acute moderate or severe illness should defer vaccination until recovery.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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