Product image of Infusio Natrii Chlorati Isotonica Imuna (Sodium Chloride) supplied by GNH India

Infusio Natrii Chlorati Isotonica Imuna

Active Ingredient:
Sodium Chloride
Origin:
EU

Infusio Natrii Chlorati Isotonica Imuna (Sodium Chloride)

Sodium Chloride, the active ingredient in Infusio Natrii Chlorati Isotonica Imuna, is an electrolyte solution presented as an injectable solution for intravenous use. It is employed to restore extracellular fluid volume and sodium chloride balance in patients requiring fluid replacement, electrolyte replenishment, or treatment of hypovolemia.

GNH India supplies Infusio Natrii Chlorati Isotonica Imuna as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to EU manufacturing standards and provides regulatory‑compliant shipments to health‑care facilities across multiple regions.

Manufacturer / TM Owner

Imuna Pharm, A.S.

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Indications & Clinical Uses

Infusio Natrii Chlorati Isotonica Imuna is used in the management of conditions that involve fluid loss or electrolyte imbalance.

  • Fluid replacement: restores intravascular volume in patients with dehydration or blood loss.
  • Electrolyte replenishment: corrects sodium and chloride deficits during surgery or illness.
  • Hypovolemia: improves circulatory stability in acute hypovolemic states.

How It Works

  • Sodium chloride infusion increases the osmolarity of the extracellular compartment, drawing water into the vascular space and expanding plasma volume. The added chloride ions contribute to the restoration of normal serum chloride concentrations, while sodium supports the maintenance of osmotic pressure and nerve‑muscle function. By matching physiological isotonicity, the solution avoids cellular swelling and rapidly corrects deficits in fluid and electrolyte balance.

Side Effects

Intravenous sodium chloride may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Phlebitis at the infusion site
  • Mild hypernatremia
  • Transient hypertension
  • Local infiltration or swelling

Serious or Rare Side Effects

  • Severe hypernatremia with neurological signs
  • Fluid overload leading to pulmonary edema
  • Anaphylactoid or allergic reactions
  • Cardiac arrhythmias from rapid sodium shifts

Precautions & Warnings

When using Infusio Natrii Chlorati Isotonica Imuna, clinicians should observe several safety measures.

  • Assess volume status: evaluate patient’s fluid balance before initiating infusion.
  • Monitor serum electrolytes: check sodium and chloride levels regularly during therapy.
  • Adjust infusion rate: tailor speed to avoid rapid shifts in plasma osmolarity.
  • Use caution in renal or cardiac impairment: risk of fluid overload.
  • Contraindications: avoid in patients with known hypersensitivity to sodium chloride solutions.
  • Store at controlled room temperature: keep in original packaging, protect from light and moisture.

Avoid Interactions

Sodium chloride infusion can interact with other agents that affect fluid and electrolyte balance.

Major Interactions (Avoid)

  • Concurrent administration of hypertonic saline solutions: may cause dangerous hypernatremia.
  • Co‑infusion with large doses of potassium chloride without monitoring: risk of severe electrolyte imbalance.

Moderate Interactions (Monitor Closely)

  • Use with loop diuretics: can amplify volume depletion.
  • Combination with corticosteroids: may increase sodium retention.
  • Concomitant use of ACE inhibitors or ARBs: monitor blood pressure and renal function.

Frequently Asked Questions

Infusio Natrii Chlorati Isotonica Imuna is an intravenous sodium chloride solution used to replace lost body fluids, restore normal electrolyte concentrations, and treat conditions such as dehydration, blood loss, or hypovolemia where rapid volume expansion is required.

The solution provides isotonic sodium and chloride ions that increase extracellular osmolarity, drawing water into the vascular compartment. This expands plasma volume, corrects sodium‑chloride deficits, and helps maintain osmotic balance and normal cellular function.

The prescribed dose is determined by the treating clinician based on the patient’s clinical condition, weight, and laboratory values. Healthcare professionals calculate the infusion volume and rate to achieve the desired fluid and electrolyte goals.

Safety data in pregnancy and lactation are limited. The product should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and it must be prescribed by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Infusio Natrii Chlorati Isotonica Imuna is an isotonic sodium chloride solution, similar to normal saline. Compared with balanced solutions such as Ringer’s lactate, it contains only sodium and chloride, making it useful when a simple electrolyte replacement is needed, but it lacks the additional electrolytes and buffers found in balanced crystalloids.

Store the injection solution at controlled room temperature, preferably below 25 °C, in its original sealed container. Protect it from direct sunlight, moisture, and extreme temperature fluctuations. Do not freeze the product, and inspect the vial for any particulate matter before use.

The product is administered intravenously using aseptic technique. It can be given as a direct infusion or added to an IV bag, with the infusion rate set by the prescriber to match the patient’s fluid‑replacement needs and to avoid rapid changes in serum sodium.

Serious risks include severe hypernatremia, fluid overload leading to pulmonary edema, and rare anaphylactoid reactions. Clinicians should monitor vital signs, serum electrolytes, and fluid balance closely, especially in patients with cardiac, renal, or pulmonary disease.

Patients with known hypersensitivity to sodium chloride solutions, those with uncontrolled hypernatremia, or individuals for whom rapid volume expansion is contraindicated (e.g., severe heart failure without monitoring) should not receive this product unless a specialist determines it is appropriate.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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