Infutraze (Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr)

• Infutraze is used to correct trace element deficiencies and support metabolic processes in patients receiving parenteral nutrition.
• Trace element deficiency: supplementation of essential minerals to restore normal biochemical function.
• Parenteral nutrition support: provides necessary trace elements to complete total nutrient formulations for patients unable to eat orally.
• Critical illness micronutrient prevention: helps prevent deficiency‑related complications in intensive care or postoperative patients.
• Renal replacement therapy: replaces trace elements removed during dialysis to maintain adequate levels.

• Infutraze delivers zinc, iodine, selenium, copper and manganese directly into the bloodstream, allowing immediate availability for cellular processes. These trace elements act as cofactors for numerous enzymes, support antioxidant defenses (e.g., selenium in glutathione peroxidase), participate in thyroid hormone synthesis (iodine), and are essential for oxidative metabolism and immune function. Intravenous administration bypasses gastrointestinal absorption, ensuring reliable delivery in patients with compromised gut function.

Infutraze may be associated with adverse reactions related to its trace element composition and intravenous administration.

Common Side Effects

• Infusion site erythema or pain
• Mild nausea or vomiting
• Transient headache
• Metallic taste
• Elevated serum copper without clinical symptoms

Serious or Rare Side Effects

• Anaphylactic or severe hypersensitivity reaction
• Copper toxicity manifesting as hepatic dysfunction
• Selenium overdose causing respiratory distress
• Manganese accumulation leading to neurotoxicity
• Severe electrolyte imbalance (e.g., hypermagnesemia)

When using Infutraze, clinicians should observe specific safety measures.

• Baseline assessment: measure serum zinc, copper and selenium levels before initiating therapy.
• Monitoring: regularly check trace element concentrations during treatment.
• Hypersensitivity: discontinue if signs of allergic reaction appear.
• Organ dysfunction: use with caution in hepatic or renal impairment, adjusting dose as needed.
• Drug compatibility: verify compatibility with other IV solutions before co‑administration.
• Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Infutraze can interact with other medications or supplements; awareness of these interactions helps maintain safety.

Major Interactions (Avoid)

• Concurrent high‑dose copper supplements: risk of copper overload.
• Concurrent high‑dose selenium preparations: risk of selenosis.

Moderate Interactions (Monitor Closely)

• Anticoagulants (e.g., heparin): trace elements may alter coagulation parameters.
• Thyroid hormone therapy: iodine content may affect hormone levels.
• Renal replacement therapy: dialysis may remove administered trace elements, requiring dose adjustment.
• Aminoglycoside antibiotics: copper may influence nephrotoxicity risk.