Product image of Infutraze (Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr) supplied by GNH India

Infutraze

Active Ingredient:
Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr
Origin:
EU

Infutraze (Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr)

Zinc chloride, potassium iodide, sodium selenite, copper chloride dihydrate, manganese chloride tetrahydrate, the active ingredients in Infutraze, are trace element supplements presented as an intravenous solution for IV use. It provides essential trace elements required for enzymatic activity and metabolic processes in patients receiving parenteral nutrition.

GNH India supplies Infutraze as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Infutraze is used to address trace element deficiencies in patients receiving parenteral nutrition.

  • Prevention of trace element deficiency: maintains adequate zinc, copper, selenium, manganese and iodine levels during total parenteral nutrition.
  • Treatment of established deficiency: restores deficient trace element concentrations to normal ranges.
  • Support for malabsorption conditions: supplies essential minerals when gastrointestinal absorption is impaired.

How It Works

  • Infutraze delivers a balanced mixture of essential trace elements that serve as cofactors for numerous enzymes, support antioxidant defenses, participate in thyroid hormone synthesis, and facilitate cellular metabolism. By replenishing zinc, copper, selenium, manganese and iodine, the formulation helps restore normal enzymatic activity and metabolic pathways that may be compromised in patients dependent on parenteral nutrition.

Side Effects

Infutraze may be associated with several adverse reactions when administered intravenously.

Common Side Effects

  • Infusion site irritation or phlebitis.
  • Mild nausea or vomiting.
  • Transient headache.
  • Metallic taste.
  • Mild transient increase in serum copper or zinc levels.

Serious or Rare Side Effects

  • Anaphylactic or severe hypersensitivity reactions.
  • Copper or zinc toxicity manifesting as hepatic dysfunction.
  • Selenium overdose leading to respiratory distress.
  • Severe electrolyte imbalance requiring medical intervention.
  • Acute renal impairment in susceptible patients.

Precautions & Warnings

When using Infutraze, clinicians should observe several safety measures.

  • Renal function: monitor serum creatinine and adjust dosing in renal impairment.
  • Hepatic function: assess liver enzymes due to potential copper accumulation.
  • Pregnancy and lactation: use only if the expected benefit outweighs potential risk.
  • Allergy assessment: verify no known hypersensitivity to any component.
  • Compatibility: confirm compatibility with other IV solutions before co‑administration.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Infutraze can interact with other agents that affect trace element balance.

Major Interactions (Avoid)

  • Concurrent high‑dose copper supplements: risk of copper overload.
  • High‑dose zinc preparations: may antagonize copper absorption.
  • Chelating agents (e.g., EDTA): can bind and reduce the availability of administered trace elements.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone therapy: excess iodine may alter hormone synthesis.
  • Antioxidant vitamins (vitamin C, E): may influence selenium status.
  • Renal dialysis: may remove administered trace elements, requiring dose adjustment.

Frequently Asked Questions

Infutraze is an intravenous trace element supplement used to prevent and treat deficiencies of zinc, copper, selenium, manganese and iodine in patients who receive parenteral nutrition, ensuring essential mineral support for metabolic and enzymatic functions.

The combination supplies essential trace elements that act as cofactors for a wide range of enzymes, support antioxidant systems, participate in thyroid hormone production, and facilitate cellular metabolism, thereby correcting deficiencies that can arise during intravenous feeding.

The prescribed dose of Infutraze is determined by the treating physician based on the patient’s individual trace element status, nutritional needs, and clinical condition. Dosage adjustments are made according to laboratory monitoring and therapeutic response.

Infutraze should be used in pregnancy or lactation only when the potential benefit to the mother outweighs any possible risk to the fetus or infant. The decision must be made by a qualified healthcare professional after careful assessment.

To order Infutraze, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Infutraze provides a balanced blend of five essential trace elements in a single IV formulation, which can simplify administration compared with using separate single‑element preparations. This integrated approach may reduce compatibility issues and streamline monitoring in patients on total parenteral nutrition.

Infutraze must be stored at 2‑8 °C, protected from light, and kept in its original container. It should not be frozen or shaken. Before use, inspect the solution for particulate matter or discoloration and allow it to reach room temperature if required for infusion.

Infutraze is administered intravenously, typically added to a compatible carrier solution and infused over a prescribed period under aseptic conditions. Administration rates and infusion volumes are set by the prescribing clinician based on patient-specific factors.

Serious risks include severe hypersensitivity reactions such as anaphylaxis, copper or zinc toxicity leading to hepatic dysfunction, selenium overdose causing respiratory distress, and significant electrolyte disturbances that may require urgent medical intervention.

Infutraze is contraindicated in patients with known hypersensitivity to any of its components, those with severe hepatic or renal impairment where trace element accumulation is likely, and in individuals where the risk of trace element overload outweighs clinical benefit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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