Product image of Infutraze (Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr) supplied by GNH India

Infutraze

Active Ingredient:
Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr
Origin:
EU

Infutraze (Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr)

Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr, the active ingredients in Infutraze, are trace element supplements presented as a sterile solution for intravenous use. They address trace element deficiencies in patients receiving parenteral nutrition, especially in critical‑care and postoperative settings.

GNH India supplies Infutraze as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, intensive‑care units and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi Ab

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Indications & Clinical Uses

  • Infutraze is used to correct trace element deficits in patients receiving parenteral nutrition and related critical‑care conditions.
  • Parenteral nutrition: supplementation of essential trace elements in patients on total parenteral nutrition.
  • Trace element deficiency: correction of low zinc, iodine, selenium, copper or manganese levels.
  • Critical care nutrition: support of metabolic processes in intensive‑care patients requiring intravenous feeding.

How It Works

  • Infutraze provides zinc, iodine, selenium, copper and manganese as ionic species that act as cofactors for numerous enzymes involved in antioxidant defence, thyroid hormone synthesis, DNA synthesis and mitochondrial respiration. By restoring these trace elements, the solution enables normal catalytic activity of metallo‑enzymes and supports cellular metabolism during intravenous feeding.

Side Effects

Infutraze may be associated with infusion‑related and systemic reactions.

Common Side Effects

  • Mild infusion site erythema or pain.
  • Transient fever or chills.
  • Nausea or mild gastrointestinal discomfort.
  • Headache.
  • Metallic taste.
  • Slight elevation of serum copper or zinc levels.

Serious or Rare Side Effects

  • Anaphylactic or severe hypersensitivity reaction.
  • Significant electrolyte imbalance (e.g., hyper‑ or hypomagnesemia).
  • Hepatic dysfunction or elevated liver enzymes.
  • Copper or selenium toxicity with prolonged high‑dose exposure.
  • Severe thrombophlebitis at the infusion site.
  • Acute renal impairment in patients with pre‑existing kidney disease.

Precautions & Warnings

  • Infutraze should be used with careful clinical monitoring.
  • Monitor trace element levels: regularly assess serum zinc, copper, selenium, manganese and iodine.
  • Assess renal function: adjust use in patients with impaired kidney function.
  • Evaluate hepatic status: watch for liver enzyme changes during therapy.
  • Caution with thyroid disorders: iodine content may affect thyroid hormone balance.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Infutraze can interact with other medications and nutrient solutions.

Major Interactions (Avoid)

  • Concurrent high‑dose copper or selenium supplements.
  • Co‑administration with other intravenous trace‑element solutions.
  • High‑dose zinc preparations that may cause copper deficiency.
  • Certain antibiotics (e.g., tetracyclines) that chelate metal ions.
  • Parenteral nutrition formulas with excessive zinc content.

Moderate Interactions (Monitor Closely)

  • Diuretics that alter electrolyte balance.
  • Thyroid hormone therapy (iodine may influence dosing).
  • Antacids containing aluminum or magnesium.
  • ACE inhibitors or ARBs affecting renal handling of electrolytes.
  • Immunosuppressants where trace‑element status may affect drug metabolism.

Frequently Asked Questions

Infutraze is a sterile intravenous solution that supplies the essential trace elements zinc, iodine, selenium, copper and manganese. It is used to prevent or correct trace‑element deficiencies in patients receiving total parenteral nutrition, especially in critical‑care, postoperative or transplant settings.

Each element serves as a cofactor for specific enzymes: zinc supports DNA synthesis and immune function; iodine is required for thyroid hormone production; selenium is a component of antioxidant enzymes; copper participates in iron metabolism and connective‑tissue formation; manganese is needed for carbohydrate metabolism. Together they restore normal enzymatic activity and metabolic balance during intravenous feeding.

The dose of Infutraze is individualized by the prescribing clinician based on the patient’s age, weight, clinical condition and laboratory trace‑element levels. The healthcare professional determines the appropriate volume and infusion rate for each case.

Safety data for Infutraze in pregnancy and lactation are limited. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the Infutraze product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and any necessary import documentation.

Infutraze provides a balanced combination of five essential trace elements in a single sterile solution, which can simplify formulation of total parenteral nutrition compared with using separate single‑element additives. Its EU‑origin manufacturing ensures compliance with stringent quality standards, offering consistent concentration and sterility.

Infutraze must be stored refrigerated at 2‑8 °C, protected from light, and should never be frozen or shaken. Before use, inspect the container for particulate matter or discoloration and allow the solution to reach room temperature if required by the infusion protocol.

Infutraze is administered intravenously, usually added to a compatible parenteral nutrition bag or infused separately according to the prescribing clinician’s instructions. The infusion rate and dilution are determined by the patient’s clinical status and the total nutrient regimen.

Serious risks include severe hypersensitivity reactions (anaphylaxis), significant electrolyte disturbances, copper or selenium toxicity with prolonged high‑dose exposure, hepatic dysfunction, and acute renal impairment in susceptible patients. Prompt recognition and discontinuation are essential if these events occur.

Infutraze should be avoided in patients with known hypersensitivity to any of its components, in those with severe hepatic or renal failure where trace‑element accumulation is a concern, and in individuals receiving incompatible intravenous solutions that could precipitate metal ions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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