Product image of Inhalok Airmaster (Fluticasone Propionate, Salmeterol) supplied by GNH India

Inhalok Airmaster

Active Ingredient:
Fluticasone Propionate, Salmeterol
Origin:
EU

Inhalok Airmaster (Fluticasone Propionate, Salmeterol)

Fluticasone propionate, the active ingredient in Inhalok Airmaster, is a inhaled corticosteroid/long‑acting β2‑adrenergic agonist presented as a fixed‑dose inhalation formulation for inhalation use. It treats asthma and chronic obstructive pulmonary disease in adults and children.

GNH India supplies Inhalok Airmaster as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU manufacturing standards for consistent quality. The company ensures regulatory compliance and reliable logistics for all markets.

Manufacturer / TM Owner

Pharmakern Portugal – Produtos Farmacêuticos, Sociedade Unipessoal, Lda.

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Indications & Clinical Uses

  • Inhalok Airmaster combines fluticasone propionate and salmeterol to manage airway inflammation and bronchoconstriction in obstructive lung diseases.
  • Asthma: improves symptom control and reduces exacerbations.
  • Chronic obstructive pulmonary disease (COPD): enhances lung function and lowers risk of flare‑ups.
  • Severe asthma requiring combination therapy: provides both anti‑inflammatory and bronchodilator effects for patients not controlled on single agents.

How It Works

  • Fluticasone propionate binds to intracellular glucocorticoid receptors, altering gene transcription to suppress inflammatory cytokines, reduce eosinophil activity, and decrease mucus production. Salmeterol selectively stimulates β2‑adrenergic receptors on bronchial smooth muscle, increasing cyclic AMP levels and causing prolonged bronchodilation, thereby improving airflow.

Side Effects

The most frequently reported adverse reactions with Inhalok Airmaster are related to local airway irritation and systemic corticosteroid exposure.

Common Side Effects

  • Oral thrush (candidiasis): mild fungal infection in the mouth.
  • Hoarseness or voice change: irritation of the vocal cords.
  • Cough or throat irritation: transient discomfort after inhalation.
  • Headache: mild to moderate intensity.

Serious or Rare Side Effects

  • Paradoxical bronchospasm: sudden worsening of breathing.
  • Adrenal suppression: reduced cortisol production with prolonged use.
  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.

Precautions & Warnings

  • Before prescribing Inhalok Airmaster, clinicians should consider several precautionary measures to minimize risks and ensure optimal therapy.
  • Rinse mouth after each inhalation: reduces risk of oral candidiasis.
  • Monitor for signs of adrenal insufficiency: especially with high‑dose or prolonged use.
  • Assess bone health periodically: long‑term corticosteroid exposure may affect bone density.
  • Use with caution in patients with cardiovascular disease: β2‑agonists can affect heart rate.
  • Avoid abrupt discontinuation: may lead to loss of asthma control.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Inhalok Airmaster may interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase systemic corticosteroid levels.
  • Non‑selective β‑blockers (e.g., propranolol): diminish bronchodilator effect of salmeterol.
  • Concurrent use of other inhaled corticosteroids: heightens risk of systemic side effects.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., furosemide): may exacerbate hypokalemia caused by β2‑agonists.
  • Anticholinergic bronchodilators: additive bronchodilation may require dose adjustment.
  • MAO inhibitors: potential for enhanced cardiovascular effects.

Frequently Asked Questions

Inhalok Airmaster is indicated for the long‑term maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD). It helps control airway inflammation and provides bronchodilation to reduce symptoms and prevent exacerbations in patients with these obstructive lung diseases.

Fluticasone propionate is a synthetic glucocorticoid that binds to intracellular glucocorticoid receptors, modulating gene transcription to suppress inflammatory cytokines, reduce eosinophil activity, and decrease mucus production in the airways, thereby lowering airway inflammation.

The prescribed dose of Inhalok Airmaster is determined by the treating physician based on the severity of the patient’s asthma or COPD, age, and response to therapy. Patients should follow the exact dosing instructions provided on the prescription label.

Safety data for fluticasone propionate/salmeterol in pregnancy and lactation are limited. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Inhalok Airmaster contains the same active ingredients—fluticasone propionate and salmeterol—as other licensed combination inhalers, offering comparable anti‑inflammatory and bronchodilator effects. Differences may lie in device design, dose strength, and regional regulatory approvals, but clinical efficacy is generally equivalent when used as directed.

The inhaler should be stored at room temperature, below 25 °C, in its original packaging. It must be kept away from moisture, heat sources, and direct sunlight to maintain dose integrity and device functionality.

Inhalok Airmaster is a fixed‑dose inhalation device. The patient inhales the prescribed number of puffs through the mouthpiece, coordinating inhalation with actuation, and then holds the breath for several seconds to allow optimal drug deposition in the lungs.

Serious adverse events include paradoxical bronchospasm, adrenal suppression, and severe allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience sudden worsening of breathing, signs of hormonal imbalance, or systemic allergic symptoms.

Inhalok Airmaster is contraindicated in individuals with known hypersensitivity to fluticasone propionate, salmeterol, or any excipients in the formulation. It should also be avoided in patients who have experienced a severe paradoxical bronchospasm after using a β2‑agonist inhaler.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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