Product image of Inhibace (Cilazapril) supplied by GNH India

Inhibace

Active Ingredient:
Cilazapril
Origin:
EU

Inhibace (Cilazapril)

Cilazapril, the active ingredient in Inhibace, is an ACE inhibitor presented as an oral dosage form for oral use. It is used to treat hypertension and heart failure in adult patients.
GNH India supplies Inhibace as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cheplapharm Arzneimittel Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Cilazapril belongs to the ACE inhibitor class and is employed in conditions where the renin‑angiotensin system contributes to elevated blood pressure or cardiac overload.

  • Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk.
  • Heart failure: improves ventricular function and decreases mortality in chronic heart failure.
  • Post‑myocardial infarction: helps prevent remodeling and reduces the chance of subsequent cardiac events.

How It Works

  • Cilazapril inhibits angiotensin‑converting enzyme, preventing the conversion of angiotensin I to the potent vasoconstrictor angiotensin II. This results in vasodilation, reduced aldosterone secretion, decreased sodium and water retention, and ultimately lower systemic vascular resistance and blood pressure.

Side Effects

Cilazapril may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Persistent dry cough
  • Dizziness or light‑headedness
  • Headache
  • Fatigue
  • Taste disturbance
  • Mild rash

Serious or Rare Side Effects

  • Angioedema (swelling of face, lips, tongue)
  • Severe hypotension
  • Hyperkalemia (elevated potassium levels)
  • Acute renal failure
  • Hepatotoxicity
  • Anaphylactic reactions

Precautions & Warnings

Before initiating Cilazapril therapy, several safety considerations should be observed.

  • Blood pressure monitoring: ensure adequate control and avoid excessive drops.
  • Renal function assessment: check serum creatinine and eGFR, especially in patients with existing kidney disease.
  • Electrolyte surveillance: monitor potassium levels to detect hyperkalemia.
  • History of angioedema: avoid use in patients with prior ACE‑inhibitor‑related swelling.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Cilazapril can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Aliskiren (in diabetic patients): combined use may increase risk of renal impairment and hyperkalemia.
  • Lithium: concurrent use can raise lithium concentrations, leading to toxicity.
  • Potassium‑sparing diuretics or supplements: may cause dangerous hyperkalemia.

Moderate Interactions (Monitor Closely)

  • NSAIDs: can blunt antihypertensive effect and affect renal function.
  • Loop or thiazide diuretics: may increase risk of hypotension, especially at therapy start.
  • Beta‑blockers: additive blood‑pressure lowering effect; monitor for bradycardia.

Frequently Asked Questions

Inhibace, containing the ACE inhibitor cilazapril, is prescribed to manage high blood pressure (hypertension) and to treat chronic heart failure. It may also be used after a heart attack to help prevent further cardiac remodeling and reduce the risk of future cardiovascular events.

Cilazapril blocks the angiotensin‑converting enzyme, which stops the formation of angiotensin II, a molecule that narrows blood vessels and stimulates aldosterone release. By reducing angiotensin II levels, blood vessels relax, blood pressure falls, and the heart experiences less strain.

The exact dose of Inhibace is determined by the prescribing clinician based on the patient’s medical condition, response to therapy, and renal function. Dosage adjustments are made individually; patients should follow the prescriber’s instructions and not alter the dose on their own.

Cilazapril is generally not recommended during pregnancy because ACE inhibitors can affect fetal kidney development and cause injury. Safety during breastfeeding has not been fully established, so the drug should only be used if the potential benefit outweighs the risk, under medical supervision.

To request Inhibace, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and necessary import documentation.

Inhibace (cilazapril) shares the same mechanism as other ACE inhibitors such as enalapril or lisinopril, providing blood‑pressure reduction and heart‑failure benefits. Differences may lie in pharmacokinetic profiles, dosing frequency, and individual tolerability, which are evaluated by the prescriber to select the most appropriate agent for each patient.

Inhibace should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency throughout its shelf life.

Inhibace is taken orally, usually as a tablet, with or without food as directed by the healthcare provider. The tablet should be swallowed whole with a glass of water; it is not intended for crushing, chewing, or sublingual administration.

The most serious adverse reactions to monitor include angioedema (swelling of the face, lips, tongue, or throat), severe hypotension, hyperkalemia, and acute kidney injury. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, sudden dizziness, or a marked drop in urine output.

Inhibace is contraindicated in individuals with a known hypersensitivity to cilazapril or any ACE inhibitor, a history of angioedema related to ACE‑inhibitor therapy, and in patients with hereditary or idiopathic angioedema. Caution is also advised for those with severe renal impairment or bilateral renal artery stenosis.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.