Product image of Inibsacain (Bupivacaine Hydrochloride, Epinephrine) supplied by GNH India

Inibsacain

Active Ingredient:
Bupivacaine Hydrochloride, Epinephrine
Origin:
EU

Inibsacain (Bupivacaine Hydrochloride, Epinephrine)

Bupivacaine Hydrochloride with Epinephrine, the active ingredient in Inibsacain, is a local anesthetic (amide type) presented as a sterile solution for dental infiltration use. It provides prolonged numbness for dental procedures and oral surgery in adult patients.
GNH India supplies Inibsacain as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Inibsa, S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Inibsacain is a local anesthetic indicated for procedures involving the oral cavity and related tissues.

  • Dental procedures: provides reliable numbness for extractions, restorations, and periodontal therapy.
  • Oral surgery: enables infiltration anesthesia for minor surgical interventions such as biopsies and soft‑tissue excisions.
  • Endodontic treatment: facilitates pain control during root‑canal therapy and related procedures.

How It Works

  • Bupivacaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of nerve impulses. The addition of epinephrine induces local vasoconstriction, reducing systemic absorption and extending the duration of anesthesia in the targeted area.

Side Effects

Adverse reactions may occur following administration of Inibsacain.

Common Side Effects

  • Transient tingling or numbness at the injection site
  • Mild headache
  • Temporary increase in heart rate
  • Localized swelling or bruising

Serious or Rare Side Effects

  • Cardiovascular toxicity such as arrhythmia or hypotension
  • Central nervous system effects including seizures or loss of consciousness
  • Severe allergic reaction (anaphylaxis)
  • Persistent paresthesia or nerve injury

Precautions & Warnings

Inibsacain should be used with attention to patient safety and proper handling.

  • Patient assessment: evaluate cardiac history and potential hypersensitivity before use.
  • Dose calculation: calculate based on body weight and maximum recommended limits.
  • Monitoring: observe for signs of systemic toxicity during and after administration.
  • Drug interactions: avoid concurrent use with other potent local anesthetics or vasoconstrictors without guidance.
  • Storage: Store below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Inibsacain may interact with other medications that affect cardiac or nervous system function.

Major Interactions (Avoid)

  • Other local anesthetics: risk of cumulative toxicity.
  • Beta‑blockers: may enhance bradycardia when combined with epinephrine.
  • Monoamine oxidase inhibitors (MAOIs): increased risk of hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: monitor for prolonged bleeding at injection site.
  • Diuretics: may alter plasma concentration of bupivacaine.
  • Calcium channel blockers: potential additive cardiac effects.

Frequently Asked Questions

Inibsacain is employed as a local anesthetic for dental infiltration, providing numbness during tooth extractions, restorative work, periodontal therapy, and minor oral surgical procedures. The combination of bupivacaine and epinephrine extends the duration of anesthesia, making it suitable for longer or more invasive dental treatments.

Bupivacaine blocks voltage‑gated sodium channels on nerve membranes, stopping the generation and transmission of electrical impulses. This interruption prevents pain signals from reaching the brain. Epinephrine added to the formulation causes local blood‑vessel constriction, slowing systemic absorption and prolonging the anesthetic effect.

The dose of Inibsacain is determined by the prescribing clinician based on the specific procedure, patient weight, and maximum safe limits. Practitioners calculate the volume required to achieve adequate anesthesia while staying within recommended safety thresholds.

Safety data for bupivacaine with epinephrine in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the Inibsacain product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Both Inibsacain (bupivacaine with epinephrine) and lidocaine are local anesthetics, but bupivacaine provides a longer duration of action, especially when combined with epinephrine. Lidocaine has a faster onset but a shorter overall effect, making bupivacaine preferable for lengthy dental or oral‑surgical procedures.

Inibsacain should be stored below 25 °C in its original container, protected from moisture and direct light. Maintaining a stable room‑temperature environment helps preserve the sterility and potency of the solution.

Inibsacain is administered by dental infiltration, where the sterile solution is injected directly into the tissues surrounding the target tooth or surgical site. The clinician follows aseptic technique and injects the calculated volume to achieve adequate numbness before the procedure begins.

Serious risks include cardiovascular toxicity such as arrhythmias or hypotension, central nervous system effects like seizures or loss of consciousness, severe allergic reactions (anaphylaxis), and persistent nerve injury leading to long‑term paresthesia. Immediate medical attention is required if any of these symptoms appear.

Patients with known hypersensitivity to bupivacaine, epinephrine, or any component of the formulation should avoid Inibsacain. It is also contraindicated in individuals with severe cardiac conduction disorders, uncontrolled hypertension, or those taking certain interacting medications without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.