Product image of Inimur (Nifuratel) supplied by GNH India

Inimur

Active Ingredient:
Nifuratel
Origin:
EU

Inimur (Nifuratel)

Nifuratel, the active ingredient in Inimur, is a nitrofuran presented as a vaginal formulation for vaginal use. It treats infections such as vaginal candidiasis, bacterial vaginosis and trichomoniasis in women.
GNH India supplies Inimur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Polichem Srl

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Indications & Clinical Uses

Nifuratel is used to treat infections of the female genital tract, targeting bacterial and fungal pathogens.

  • Vaginal candidiasis: eliminates Candida species and relieves itching, discharge and irritation.
  • Bacterial vaginosis: reduces overgrowth of anaerobic bacteria and helps restore normal vaginal flora.
  • Trichomoniasis: eradicates Trichomonas vaginalis infection and clears associated symptoms.

How It Works

  • Nifuratel interferes with microbial DNA synthesis and disrupts cell membrane integrity, leading to inhibition of bacterial and fungal growth. By targeting essential nucleic acid processes and membrane function, it provides broad‑spectrum antibacterial and antifungal activity within the vaginal environment.

Side Effects

Nifuratel may cause local or systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Local irritation: burning or itching at the application site.
  • Vaginal discharge: mild watery or whitish discharge.
  • Headache: transient mild headache.
  • Nausea: occasional mild nausea.

Serious or Rare Side Effects

  • Allergic reaction: rash, swelling, or anaphylaxis.
  • Severe vaginal inflammation: persistent ulceration or intense irritation.
  • Hepatic dysfunction: abnormal liver enzymes (rare).

Precautions & Warnings

Use of Inimur requires attention to several safety considerations.

  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: unknown safety; weigh potential risks against benefits.
  • Allergies: avoid if hypersensitivity to nitrofurans is known.
  • Concomitant vaginal products: do not use other intravaginal medications simultaneously.
  • Medical conditions: caution in patients with liver disease.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Nifuratel may interact with other medicines, requiring awareness of potential effects.

Major Interactions (Avoid)

  • Antifungal azoles: may reduce the efficacy of Nifuratel.
  • Systemic antibiotics: concurrent use may alter vaginal flora and affect treatment outcome.

Moderate Interactions (Monitor Closely)

  • Hormonal contraceptives: vaginal irritation may affect absorption; monitor effectiveness.
  • Vaginal douches or spermicides: may interfere with drug action.
  • Immunosuppressants: monitor for increased infection risk.

Frequently Asked Questions

Inimur is indicated for the treatment of vaginal infections, specifically vaginal candidiasis, bacterial vaginosis and trichomoniasis. It is applied directly to the vagina to eradicate the responsible microorganisms and relieve associated symptoms such as itching, discharge and irritation.

Nifuratel exerts its antimicrobial effect by inhibiting microbial DNA synthesis and disrupting cell‑membrane function. This dual action interferes with the replication of bacteria and fungi, leading to their death and providing both antibacterial and antifungal activity within the vaginal environment.

The dosage regimen for Inimur is determined by the prescribing healthcare professional based on the specific infection, severity and patient characteristics. Patients should follow the prescriber’s instructions and the product label; no standard dose is provided here.

Safety data for Nifuratel in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To order Inimur, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

The most common alternative for vaginal infections is metronidazole, a nitroimidazole. Compared with metronidazole, Nifuratel offers both antibacterial and antifungal activity, which can be advantageous in mixed infections. However, clinical choice depends on pathogen susceptibility, patient tolerance and local treatment guidelines.

Inimur should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and heat sources to maintain its stability and efficacy.

Inimur is administered intravaginally. The prescribed amount is inserted into the vagina using the supplied applicator or as directed by the healthcare professional, typically once or twice daily for the duration specified by the prescriber.

Serious adverse reactions, although rare, include allergic responses such as rash, swelling or anaphylaxis, severe vaginal inflammation or ulceration, and hepatic dysfunction indicated by abnormal liver enzymes. Patients should seek immediate medical attention if any of these symptoms occur.

Inimur should be avoided in individuals with known hypersensitivity to Nifuratel or other nitrofurans, in pregnant women unless clearly necessary, and in patients with severe liver disease where drug metabolism may be impaired. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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