Product image of Inj. Natrii Chlorati Polpharma (Sodium Chloride) supplied by GNH India

Inj. Natrii Chlorati Polpharma

Active Ingredient:
Sodium Chloride
Origin:
EU

Inj. Natrii Chlorati Polpharma (Sodium Chloride)

Sodium chloride, the active ingredient in Inj. Natrii Chlorati Polpharma, is an electrolyte solution presented as an injection for intravenous use. It provides sodium and chloride ions to restore extracellular fluid volume and correct electrolyte imbalances in patients who require fluid replacement, such as those with hyponatremia, postoperative fluid loss, or severe dehydration.

GNH India supplies Inj. Natrii Chlorati Polpharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

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Indications & Clinical Uses

Inj. Natrii Chlorati Polpharma is an intravenous electrolyte solution used in clinical situations that require fluid and electrolyte management.

  • Fluid replacement: restores intravascular volume in patients with blood loss, dehydration or surgical fluid loss.
  • Electrolyte replenishment: supplies sodium and chloride to correct deficits during illness or treatment.
  • Treatment of hyponatremia: raises serum sodium concentration in patients with low sodium levels.
  • Diluent for intravenous drug administration: serves as a compatible carrier for reconstituting and delivering other IV medications.

How It Works

  • Sodium chloride injection delivers sodium (Na⁺) and chloride (Cl⁻) ions directly into the bloodstream. These ions expand the extracellular fluid compartment, increase plasma osmolality, and help re‑establish osmotic equilibrium. By augmenting intravascular volume, the solution supports blood pressure, tissue perfusion, and normal cellular function while correcting hyponatremia and chloride deficits.

Side Effects

Adverse reactions to sodium chloride injection may vary in frequency and severity.

Common Side Effects

  • Injection site pain or erythema.
  • Mild hypernatremia leading to thirst.
  • Edema or peripheral swelling.
  • Headache.
  • Nausea.

Serious or Rare Side Effects

  • Severe hypernatremia with neurological symptoms.
  • Anaphylactic or severe allergic reaction.
  • Volume overload causing pulmonary edema.
  • Cardiac arrhythmia due to electrolyte imbalance.
  • Acute renal failure in susceptible patients.

Precautions & Warnings

When using Inj. Natrii Chlorati Polpharma, clinicians should observe several safety considerations.

  • Assess fluid status: evaluate volume needs before infusion.
  • Monitor serum electrolytes: check sodium and chloride levels regularly.
  • Adjust infusion rate in cardiac or renal disease: avoid rapid administration.
  • Use caution in neonates and pediatric patients: dose and rate must be individualized.
  • Avoid rapid infusion in patients with heart failure: risk of volume overload.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Sodium chloride injection can influence or be influenced by other therapies.

Major Interactions (Avoid)

  • Concomitant hypertonic saline solutions: may cause severe hypernatremia.
  • Potassium chloride infusions administered simultaneously: risk of electrolyte imbalance.
  • Loop diuretics given in high doses: can exacerbate sodium loss.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may affect renal handling of sodium.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): can alter renal perfusion.
  • Corticosteroids: may increase sodium retention and fluid retention.

Frequently Asked Questions

Inj. Natrii Chlorati Polpharma is a sterile sodium chloride injection used to replace lost fluids, replenish sodium and chloride electrolytes, treat hyponatremia, and act as a compatible diluent for the preparation and administration of other intravenous medications.

The sodium chloride solution provides Na⁺ and Cl⁻ ions that expand the extracellular fluid volume, increase plasma osmolality, and help restore the normal balance of electrolytes. This supports blood pressure, tissue perfusion, and cellular function, especially when patients have lost fluids or have low serum sodium.

The prescribed dose of Inj. Natrii Chlorati Polpharma is individualized by the treating clinician based on the patient’s fluid status, electrolyte levels, body weight, and the clinical indication. Dosage calculations consider the desired rate of volume expansion and target serum sodium concentration.

Safety data for sodium chloride injection in pregnancy and lactation are limited, and the product does not have a specific pregnancy category. Clinicians should weigh the potential benefits against any possible risks and use the product only if clearly indicated by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and any required import documentation.

Inj. Natrii Chlorati Polpharma is essentially a sterile sodium chloride solution similar to normal saline (0.9% NaCl). Both provide isotonic fluid replacement, but formulation specifics, packaging, and regulatory status may differ. Clinicians choose the product that best fits their supply chain, labeling requirements, and institutional preferences.

Store Inj. Natrii Chlorati Polpharma at 2‑8 °C (refrigerated). Keep the vials in the original packaging, protect them from light, and do not freeze or shake the product. Maintaining the cold chain preserves solution stability and sterility.

The product is administered intravenously, either as a direct infusion or added to an IV line as a diluent for other medications. Administration should follow aseptic technique, using appropriate infusion sets, and the rate should be adjusted according to the patient’s clinical condition and physician orders.

Serious risks include severe hypernatremia, anaphylactic reactions, volume overload leading to pulmonary edema, cardiac arrhythmias from electrolyte disturbances, and acute renal failure in susceptible patients. Prompt recognition of symptoms and regular monitoring of electrolytes and fluid status are essential.

Patients with known hypersensitivity to sodium chloride solutions, those with uncontrolled severe hypernatremia, or individuals at high risk of fluid overload (e.g., severe heart failure, uncontrolled hypertension) should not receive this injection unless a clinician determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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