Product image of Innovair (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous) supplied by GNH India

Innovair

Active Ingredient:
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Origin:
EU

Innovair (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous)

Formoterol fumarate dihydrate / beclometasone dipropionate anhydrous, the active ingredient in Innovair, is an inhaled corticosteroid/long‑acting β2‑adrenergic agonist (ICS/LABA) presented as an inhalation aerosol (metered‑dose inhaler) for inhalation use. It delivers combined anti‑inflammatory and bronchodilator effects for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adults and adolescents.

GNH India supplies Innovair as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for respiratory therapeutics.

Manufacturer / TM Owner

Chiesi Farmaceutici S.P.A.

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Indications & Clinical Uses

Innovair is an inhaled combination therapy that targets airway inflammation and bronchoconstriction in chronic respiratory disease.

  • Asthma: provides long‑term control of symptoms and reduces the risk of severe attacks.
  • Chronic obstructive pulmonary disease (COPD): improves airflow limitation and decreases the frequency of exacerbations.
  • Patients requiring combined inhaled corticosteroid and long‑acting β2‑agonist therapy: offers convenient once‑daily maintenance dosing.

How It Works

  • Formoterol fumarate dihydrate activates β2‑adrenergic receptors on airway smooth muscle, causing relaxation and bronchodilation, while beclometasone dipropionate binds glucocorticoid receptors, modulating gene transcription to suppress inflammatory cytokine production and reduce airway edema. The dual action restores airflow and limits chronic inflammation in the respiratory tract.

Side Effects

Innovair may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Throat irritation or soreness
  • Hoarseness or voice change
  • Cough after inhalation
  • Oral candidiasis (thrush)

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe allergic reaction (anaphylaxis)
  • Cardiovascular effects such as tachycardia or palpitations

Precautions & Warnings

Before prescribing Innovair, clinicians should consider several safety aspects.

  • Assess infection risk: avoid initiating during active respiratory infections.
  • Monitor growth in children: schedule periodic height and weight assessments.
  • Ensure correct inhaler technique: educate patients on priming and breath‑hold.
  • Avoid abrupt discontinuation: may lead to loss of asthma control.
  • Store at room temperature below 25°C: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Innovair can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Beta‑blockers: may diminish bronchodilator effect and precipitate bronchospasm.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): can raise systemic corticosteroid levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance the risk of hypokalemia when combined with β2‑agonists.
  • Theophylline: concurrent use may increase the likelihood of cardiac arrhythmias.
  • Other inhaled corticosteroids: combined use may increase systemic steroid exposure.

Frequently Asked Questions

Innovair is a fixed‑dose inhaler that combines a corticosteroid with a long‑acting β2‑agonist. It is prescribed for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) to improve lung function, reduce symptoms, and lower the risk of exacerbations.

Formoterol stimulates β2‑adrenergic receptors on airway smooth muscle, causing rapid relaxation and bronchodilation. Beclometasone binds glucocorticoid receptors, altering gene expression to suppress inflammatory mediators, reduce airway swelling, and prevent mucus overproduction. Together they provide both immediate and long‑term control of airway narrowing.

The prescribed dose of Innovair is determined by the treating physician based on the patient’s age, severity of disease, and response to therapy. Patients should follow the specific inhalation instructions provided by their healthcare professional and never adjust the dose without medical guidance.

Safety data for Innovair in pregnancy and lactation are limited. The decision to use the inhaler should be made by a qualified healthcare provider after weighing the potential benefits for the mother against any possible risks to the fetus or infant.

To request Innovair, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Innovair offers a convenient single‑inhaler solution that combines an inhaled corticosteroid and a long‑acting β2‑agonist, reducing the need for multiple devices. Compared with separate inhalers, it may improve adherence and simplify dosing, while delivering comparable efficacy to other approved ICS/LABA combinations.

Innovair should be stored at room temperature below 25 °C, protected from moisture and direct sunlight. Keep the inhaler in its original packaging until use, and avoid exposing it to extreme heat or freezing conditions to maintain dose integrity.

Innovair is delivered via a metered‑dose inhaler. Patients should shake the device, prime it according to the manufacturer’s instructions, exhale fully, then inhale slowly and deeply while actuating the inhaler. A breath‑hold for about 10 seconds after inhalation helps maximize drug deposition.

Serious risks include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, and cardiovascular effects like tachycardia or palpitations. Patients should seek immediate medical attention if they experience sudden worsening of breathing, throat swelling, rash, or rapid heartbeat after using the inhaler.

Innovair is contraindicated in patients with a known hypersensitivity to either formoterol, beclometasone, or any excipients in the formulation. It should also be avoided in individuals who have experienced a severe paradoxical bronchospasm with a similar medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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