Product image of Instillagel (Chlorhexidine Gluconate, Lidocaine Hydrochloride) supplied by GNH India

Instillagel

Active Ingredient:
Chlorhexidine Gluconate, Lidocaine Hydrochloride
Origin:
EU

Instillagel (Chlorhexidine Gluconate, Lidocaine Hydrochloride)

Chlorhexidine Gluconate and Lidocaine Hydrochloride, the active ingredients in Instillagel, are an antiseptic and a local anesthetic presented as a gel for urethral use. They help prevent infection and relieve discomfort during catheterisation procedures.
GNH India supplies Instillagel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Melisana Nv

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Instillagel, a combination antiseptic and local anesthetic gel, is used in the urogenital tract to prevent infection and reduce discomfort during catheterisation.

  • Catheter‑associated urinary tract infection prevention: reduces bacterial colonisation during catheter insertion.
  • Urethral pain relief: provides local anaesthesia to alleviate discomfort associated with catheterisation.
  • Pre‑procedural urethral preparation: cleanses the urethra before diagnostic or therapeutic procedures.

How It Works

  • Chlorhexidine gluconate disrupts bacterial cell membranes, leading to cell death, while lidocaine hydrochloride blocks voltage‑gated sodium channels in nerve membranes, preventing depolarisation and providing local anaesthesia. The combined actions give both antiseptic protection and analgesic effect at the site of urethral application.

Side Effects

Instillagel may cause local reactions after urethral application.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Mild urethral irritation or redness.
  • Transient urinary urgency or frequency.
  • Mild allergic skin reaction such as rash.

Serious or Rare Side Effects

  • Anaphylaxis or severe hypersensitivity reaction.
  • Severe urethral inflammation or chemical cystitis.
  • Tissue necrosis or ulceration at the site of application.

Precautions & Warnings

Before using Instillagel, consider the following precautions.

  • Allergy assessment: verify no known hypersensitivity to chlorhexidine or lidocaine.
  • Intended use only: apply exclusively to the urethra as directed.
  • Compromised urethral integrity: avoid if the urethral mucosa is severely damaged.
  • Monitor for allergic signs: discontinue if rash, swelling, or breathing difficulty occurs.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Instillagel may interact with other medications or products.

Major Interactions (Avoid)

  • Concurrent use of other topical anesthetics: may cause additive local toxicity.
  • Simultaneous application of additional chlorhexidine‑containing products: increases risk of irritation.

Moderate Interactions (Monitor Closely)

  • Use with catheters impregnated with other antimicrobials: may alter efficacy.
  • Concomitant systemic steroids or wound‑healing agents: could affect local tissue response.
  • Combination with other local antiseptics: may increase irritation or chemical injury risk.

Frequently Asked Questions

Instillagel is a sterile gel containing chlorhexidine gluconate and lidocaine hydrochloride that is applied to the urethra before catheter insertion. It helps prevent urinary tract infections by providing antiseptic action and reduces discomfort by delivering local anaesthesia during catheterisation procedures.

Chlorhexidine gluconate acts as a broad‑spectrum antiseptic by binding to bacterial cell walls and disrupting membrane integrity, leading to leakage of intracellular contents and cell death. This antimicrobial activity reduces bacterial colonisation of the urethra during catheter use.

The specific amount of Instillagel to be instilled into the urethra is determined by the prescribing clinician based on the procedure and patient needs. The prescriber will specify the volume to be administered immediately before catheter insertion.

Safety data for Instillagel in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any potential risk to the mother or infant, and the decision should be made by a qualified healthcare professional.

To order Instillagel, submit an enquiry on the product page at gnhindia.com, providing the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then replies with pricing, availability, shipping details and any necessary import documentation.

Unlike simple lubricants, Instillagel combines an antiseptic (chlorhexidine) with a local anaesthetic (lidocaine), offering both infection control and pain relief. Conventional lubricants provide only friction reduction, so Instillagel may provide added clinical benefits in preventing catheter‑associated infections and improving patient comfort.

Instillagel should be stored at room temperature, preferably below 25 °C, in its original sealed container. Protect the gel from direct sunlight, excessive heat and moisture. Do not freeze or expose it to extreme temperatures, and keep it out of reach of children.

Instillagel is administered by a healthcare professional who instills a prescribed volume of the gel directly into the urethra using a sterile applicator or catheter lumen, typically immediately before catheter insertion. The gel spreads along the urethral mucosa to provide antiseptic and analgesic effects.

The most serious risks include severe allergic reactions such as anaphylaxis, significant urethral inflammation or chemical cystitis, and rare cases of tissue necrosis. Immediate medical attention is required if signs of a severe reaction, such as difficulty breathing, swelling, or intense pain, occur.

Instillagel should not be used in individuals with a known hypersensitivity to chlorhexidine, lidocaine, or any component of the formulation. It is also contraindicated in patients with severe urethral injury or ulceration where the gel could exacerbate tissue damage.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.