Product image of Instillagel (Chlorhexidine Gluconate, Methyl Parahydroxybenzoate, Propyl Parahydroxybenzoate, Lidocaine Hydrochlo) supplied by GNH India

Instillagel

Active Ingredient:
Chlorhexidine Gluconate, Methyl Parahydroxybenzoate, Propyl Parahydroxybenzoate, Lidocaine Hydrochlo
Origin:
EU

Instillagel (Chlorhexidine Gluconate, Methyl Parahydroxybenzoate, Propyl Parahydroxybenzoate, Lidocaine Hydrochlo)

Chlorhexidine gluconate, the active ingredient in Instillagel, is an antiseptic presented as a gel for oropharyngeal, rectal, urethral and vaginal use. It provides broad‑spectrum antimicrobial protection and local anaesthetic relief on mucosal surfaces of adults.
GNH India supplies Instillagel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farco-Pharma Gmbh

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Indications & Clinical Uses

Instillagel is an antiseptic/ local‑anaesthetic gel used on mucosal surfaces to reduce microbial load and provide temporary numbness.

  • Oral cavity antisepsis: reduces bacterial count in the mouth before dental or surgical procedures.
  • Rectal antisepsis: cleans the rectal mucosa prior to examinations or interventions.
  • Urethral antisepsis: prepares the urethra for catheterisation or diagnostic tests.
  • Vaginal antisepsis: helps maintain a low‑microbial environment before gynecological examinations.

How It Works

  • Chlorhexidine gluconate disrupts bacterial cell membranes by binding to phospholipids, leading to leakage of intracellular contents and cell death. Lidocaine hydrochloride blocks voltage‑gated sodium channels in peripheral nerves, producing reversible loss of sensation. Methylparaben and propylparaben act as preservatives, preventing microbial growth in the gel matrix, thereby maintaining product stability during storage and use.

Side Effects

Instillagel may cause local reactions, most of which are mild and transient.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Mild itching or tingling.
  • Transient alteration of taste.
  • Temporary redness of the mucosa.
  • Mild numbness that resolves within minutes.
  • Slight swelling of the applied area.

Serious or Rare Side Effects

  • Allergic reaction including anaphylaxis.
  • Severe mucosal irritation or ulceration.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Contact dermatitis extending beyond the application site.
  • Systemic toxicity from lidocaine (rare).

Precautions & Warnings

Before using Instillagel, consider the following safety measures.

  • Hypersensitivity: avoid if known allergy to chlorhexidine, lidocaine, or parabens.
  • Open wounds: do not apply to extensive broken skin unless directed by a clinician.
  • Mucosal use only: limit application to oral, rectal, urethral or vaginal mucosa as indicated.
  • Monitor: watch for signs of allergic reaction such as rash, swelling or difficulty breathing.
  • Children: keep out of reach of children and use only under professional supervision.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Instillagel can interact with other agents applied to the same mucosal area.

Major Interactions (Avoid)

  • Concurrent topical anesthetics: may increase systemic lidocaine exposure.
  • Additional chlorhexidine products: can cause cumulative irritation.
  • Otic preparations: avoid use in the ear due to risk of ototoxicity.

Moderate Interactions (Monitor Closely)

  • Alcohol‑based mouthwashes: may reduce antiseptic efficacy.
  • Anticoagulants: monitor for increased bleeding if mucosal irritation occurs.
  • Systemic antibiotics: may alter normal flora but generally do not contraindicate use.

Frequently Asked Questions

Instillagel is a chlorhexidine‑based antiseptic gel that also contains lidocaine for local anaesthesia. It is applied to the oral cavity, rectum, urethra or vagina to reduce microbial load before examinations, procedures or catheterisation, providing both antimicrobial protection and temporary numbness.

Chlorhexidine disrupts bacterial cell membranes by binding to phospholipids, causing leakage of intracellular components and cell death. This broad‑spectrum action reduces the number of bacteria on mucosal surfaces, while lidocaine blocks sodium channels to produce a reversible loss of sensation.

The dose of Instillagel is determined by the prescribing clinician based on the specific procedure and anatomical site. The product is supplied as a gel that is applied in a thin layer to the targeted mucosa, and the amount used is guided by professional medical judgment.

Safety data for Instillagel in pregnancy and lactation are limited. It should be used only if clearly needed and after a risk‑benefit assessment by the healthcare provider. Women who are pregnant or breastfeeding should discuss potential risks with their clinician before use.

To order Instillagel, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Instillagel combines chlorhexidine, a well‑established antiseptic, with lidocaine for local anaesthesia, offering both antimicrobial action and pain relief. Many alternative gels contain only antiseptic agents without anaesthetic, so Instillagel may provide added comfort during procedures, though choice depends on clinical needs and patient tolerance.

Instillagel should be stored at room temperature, below 25 °C, in its original packaging. Protect the gel from moisture, direct sunlight and extreme temperatures. Keep the container tightly closed when not in use to maintain product stability.

Instillagel is applied topically to the targeted mucosal surface. A thin layer is spread using a sterile applicator or gloved finger, covering the area to be treated. The gel is left in place for the duration recommended by the clinician, after which it may be rinsed or left to dissolve naturally.

The most serious risks include allergic reactions such as anaphylaxis, severe mucosal irritation, and rare systemic toxicity from lidocaine. Users should be monitored for signs of rash, swelling, difficulty breathing, or persistent ulceration, and medical attention should be sought immediately if these occur.

Instillagel should not be used by individuals with known hypersensitivity to chlorhexidine, lidocaine, methylparaben, or propylparaben. It is also contraindicated on extensive open wounds, in the ear canal, or in patients where local anaesthesia is contraindicated without prior medical evaluation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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