Instillagel (Chlorhexidine Gluconate, Methyl Parahydroxybenzoate, Propyl Parahydroxybenzoate, Lidocaine Hydrochlo)

Chlorhexidine gluconate acts by binding to bacterial cell membranes, disrupting their structure and causing leakage of intracellular contents, which leads to rapid cell death. This broad‑spectrum antimicrobial activity reduces the risk of infection on the treated mucosal surfaces.

The amount of Instillagel to be applied is determined by the prescribing clinician based on the procedure and the size of the mucosal area. Typically, a thin layer is spread over the target site immediately before the intervention, but exact dosing instructions must come from a qualified health professional.

Safety data for Instillagel in pregnancy and lactation are limited. It should only be used when clearly needed and after a risk‑benefit assessment by the treating physician. If used, the prescriber should monitor both mother and infant closely.

To request Instillagel, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Compared with povidone‑iodine gels, Instillagel offers both antimicrobial activity and immediate local anaesthesia due to its lidocaine component. This dual action can improve patient comfort during procedures, whereas povidone‑iodine provides only antisepsis and may cause more stinging on sensitive mucosa.

Instillagel should be stored at room temperature, below 25 °C, in its original sealed container. Keep the product away from moisture, direct sunlight and extreme temperatures. Do not freeze the gel, and ensure the cap is tightly closed after each use to maintain sterility.

Instillagel is applied topically to the target mucosal surface. The clinician spreads a thin layer of the gel over the rectal, urethral or vaginal area using a sterile applicator or gloved finger, allowing it to act for a few minutes before proceeding with the planned procedure.

The most serious risks include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome or toxic epidermal necrolysis, and rare systemic toxicity from lidocaine absorption. Any signs of widespread rash, difficulty breathing, swelling, or persistent numbness should prompt immediate medical attention.

Instillagel should be avoided in individuals with known hypersensitivity to chlorhexidine, lidocaine, methyl‑ or propyl‑parahydroxybenzoate (parabens), or any other component of the formulation. It is also contraindicated on severely damaged, ulcerated or compromised mucosal tissue and should not be applied to the eyes.