Instillido (Lidocaine Hydrochloride)

Lidocaine hydrochloride works by reversibly blocking voltage‑gated sodium channels on nerve cells. This prevents the initiation and propagation of action potentials, thereby inhibiting the transmission of pain signals from the urethral tissue to the brain and producing localized numbness.

The appropriate dose of Instillido is determined by the prescribing clinician based on the specific procedure, patient characteristics, and clinical guidelines. Healthcare professionals calculate the volume needed to achieve adequate urethral anesthesia while staying within safety limits.

Safety data for lidocaine hydrochloride in pregnancy and lactation are limited. Use of Instillido during pregnancy or while breastfeeding should only be considered if the potential benefit justifies any potential risk to the fetus or infant, and it must be prescribed by a qualified healthcare provider.

To order Instillido, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details, and any required import documentation.

Instillido’s active ingredient, lidocaine hydrochloride, is a widely used amide‑type local anesthetic offering rapid onset and moderate duration of action. Compared with alternatives such as benzocaine or tetracaine, lidocaine provides a balanced profile of efficacy and safety for urethral applications, with a well‑characterized toxicity threshold.

Instillido should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from direct light, moisture, and extreme temperature fluctuations. Ensure the container is tightly sealed when not in use to maintain sterility.

Instillido is administered by instilling the sterile solution directly into the urethra using a suitable applicator or catheter. The exact volume and technique are determined by the treating clinician, who ensures uniform coverage of the urethral mucosa before the procedure begins.

The most serious risks include systemic lidocaine toxicity, which can manifest as central nervous system symptoms (e.g., seizures, confusion) or cardiac effects (e.g., arrhythmias, hypotension). Additionally, allergic reactions such as rash, angioedema, or anaphylaxis may occur and require immediate medical attention.

Instillido should not be used in patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics. Caution is also advised for individuals with severe hepatic impairment, significant cardiac conduction disorders, or those receiving interacting medications that could increase lidocaine toxicity.