Instillido (Lidocaine Hydrochloride)

Lidocaine reversibly blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of nerve impulses. By stabilizing the neuronal membrane, it inhibits transmission of pain signals from the urethral tissue, resulting in a temporary loss of sensation in the treated area.

The specific dose of Instillido is determined by the prescribing clinician based on the type and duration of the urologic procedure, the patient’s age, weight, and overall health. The prescriber will calculate the appropriate volume and concentration to achieve effective urethral anesthesia while minimizing systemic exposure.

Safety data for lidocaine use in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. The prescriber must evaluate the clinical situation and consider alternative options if uncertainty exists.

To request Instillido, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Instillido contains lidocaine, a widely used amide‑type local anesthetic known for rapid onset and moderate duration. Compared with ester‑type agents such as procaine, lidocaine generally provides a faster onset, longer analgesic effect, and a lower incidence of allergic reactions, making it a preferred choice for urethral anesthesia.

Instillido should be stored at room temperature, preferably below 25 °C, in its original sealed container. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations. Maintaining these conditions helps preserve sterility and potency until the time of use.

Instillido is administered directly into the urethra using a sterile applicator or catheter as directed by the healthcare professional. The solution is instilled in the appropriate volume to coat the urethral mucosa, allowing the lidocaine to take effect within minutes before the procedure begins.

Although rare, serious adverse events can include systemic lidocaine toxicity, manifested as central nervous system symptoms (e.g., seizures, confusion) or cardiovascular effects (e.g., arrhythmias, hypotension). Allergic reactions such as rash, angioedema, or anaphylaxis also require immediate medical attention.

Instillido should be avoided in patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics. It is also contraindicated in individuals with severe hepatic impairment, certain cardiac conduction disorders, or those receiving concurrent medications that significantly increase lidocaine plasma levels without careful monitoring.