Product image of Insucor (Nebivolol Hydrochloride) supplied by GNH India

Insucor

Active Ingredient:
Nebivolol Hydrochloride
Origin:
EU

Insucor (Nebivolol Hydrochloride)

Nebivolol Hydrochloride, the active ingredient in Insucor, is a beta blocker presented as a tablet for oral use. It treats hypertension and heart failure in adults.
GNH India supplies Insucor as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nebivolol is a selective β1‑adrenergic blocker used in cardiovascular disease management.

  • Hypertension: lowers systemic blood pressure and reduces cardiovascular risk.
  • Heart failure: improves left ventricular function and decreases hospitalization rates.

How It Works

  • Nebivolol selectively antagonizes β1‑adrenergic receptors, reducing heart rate and myocardial contractility, while simultaneously enhancing endothelial nitric oxide release, which promotes vasodilation and further contributes to blood pressure reduction.

Side Effects

Nebivolol may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Dizziness: especially upon standing.
  • Fatigue: general tiredness.
  • Nausea: occasional upset stomach.
  • Bradycardia: slower than normal heart rate.
  • Peripheral edema: mild swelling of ankles.

Serious or Rare Side Effects

  • Severe bradycardia: markedly low heart rate requiring medical attention.
  • Heart block: impaired electrical conduction.
  • Bronchospasm: difficulty breathing, especially in patients with asthma.
  • Allergic reactions: rash, itching, or swelling.
  • Hepatic dysfunction: abnormal liver enzymes.
  • Hypotension: dangerously low blood pressure.

Precautions & Warnings

Before prescribing Nebivolol, clinicians should consider several safety measures.

  • Blood pressure monitoring: check regularly to ensure therapeutic control.
  • Cardiac function assessment: evaluate baseline cardiac status.
  • Asthma or COPD caution: use with care due to possible bronchoconstriction.
  • Concomitant beta‑blocker use: avoid additive negative chronotropic effects.
  • Renal impairment adjustment: dose may need modification in reduced kidney function.
  • Store at room temperature: keep in original container, protect from moisture.

Avoid Interactions

Nebivolol interacts with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Other β‑blockers: additive negative chronotropic effects.
  • Calcium channel blockers (verapamil, diltiazem): increased bradycardia risk.
  • Potent CYP2D6 inhibitors (paroxetine, fluoxetine): elevated nebivolol plasma levels.
  • Antiarrhythmic agents (quinidine): enhanced cardiac conduction slowing.
  • Clonidine withdrawal: may cause rebound hypertension.

Moderate Interactions (Monitor Closely)

  • Diuretics: may potentiate hypotensive effect.
  • ACE inhibitors or ARBs: combined blood pressure lowering.
  • NSAIDs: may reduce antihypertensive efficacy.
  • Digoxin: monitor for bradycardia.
  • Alcohol: can increase dizziness.

Frequently Asked Questions

Insucor, containing nebivolol, is prescribed for the management of hypertension and for patients with chronic heart failure. In both conditions it helps lower blood pressure and improve cardiac function, reducing the risk of cardiovascular complications.

Nebivolol selectively blocks β1‑adrenergic receptors, which slows heart rate and reduces the force of contraction. At the same time it stimulates nitric oxide release from the endothelium, causing blood vessels to relax and widen, thereby lowering systemic blood pressure.

The dose of Insucor is individualized by the prescribing healthcare professional based on the patient’s medical condition, response to therapy, and other factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of nebivolol in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To request Insucor, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nebivolol is a highly selective β1‑blocker with the added property of nitric‑oxide‑mediated vasodilation, which may result in fewer metabolic side effects compared with non‑selective beta blockers. Its profile makes it a preferred option for patients needing both heart rate control and vasodilation.

Insucor should be stored at room temperature, below 25 °C, in its original packaging. Protect the tablets from moisture and direct sunlight to maintain potency throughout the shelf life.

Insucor is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious risks include severe bradycardia, heart block, bronchospasm in patients with reactive airway disease, and significant hypotension. Patients should be monitored for symptoms such as fainting, shortness of breath, or unusually slow heart rate and seek medical attention promptly.

Insucor is contraindicated in individuals with known hypersensitivity to nebivolol or any component of the formulation, in patients with severe bradycardia, second‑ or third‑degree atrioventricular block without a pacemaker, and in those with uncompensated heart failure or severe asthma/COPD.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Nebivolol Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT