Product image of Insulatard (Insulin Human) supplied by GNH India

Insulatard

Active Ingredient:
Insulin Human
Origin:
EU

Insulatard (Insulin Human)

Insulin Human, the active ingredient in Insulatard, is an insulin presented as an injectable solution for subcutaneous administration. It is used to lower blood glucose levels in patients with type 1 and type 2 diabetes mellitus, providing basal insulin coverage to maintain glycaemic control.

GNH India supplies Insulatard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches for global distribution. Customers benefit from reliable cold‑chain logistics and dedicated technical support.

Manufacturer / TM Owner

Novo Nordisk A/S

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Indications & Clinical Uses

Insulatard, a long‑acting insulin analogue, is used in the management of diabetes mellitus.

  • Type 1 diabetes mellitus: provides basal insulin to control fasting glucose levels.
  • Type 2 diabetes mellitus: supplements endogenous insulin to achieve glycaemic targets.
  • Basal insulin therapy: maintains steady insulin levels between meals and overnight.

How It Works

  • Insulin Human binds to insulin receptors on muscle, adipose and hepatic cells, activating the receptor’s intrinsic tyrosine kinase activity. This triggers intracellular signaling cascades that promote glucose uptake, glycogen synthesis, and inhibition of hepatic gluconeogenesis, thereby lowering plasma glucose concentrations and providing sustained basal insulin activity.

Side Effects

Adverse reactions may occur with any insulin therapy.

Common Side Effects

  • Hypoglycaemia: low blood sugar episodes, especially if meals are missed or dose is excessive.
  • Injection site reactions: redness, swelling, or itching at the injection site.
  • Weight gain: increase in body weight due to improved glucose utilization.
  • Lipodystrophy: localized changes in subcutaneous fat at injection sites.
  • Edema: mild fluid retention, particularly in the lower extremities.

Serious or Rare Side Effects

  • Severe hypoglycaemia with seizures or loss of consciousness.
  • Allergic reactions including anaphylaxis, urticaria, or angioedema.
  • Insulin antibody formation that may alter insulin action.
  • Lipohypertrophy leading to erratic insulin absorption.
  • Hypokalemia: low potassium levels in rare cases.

Precautions & Warnings

Use Insulatard with careful monitoring and appropriate patient education.

  • Blood glucose monitoring: check levels regularly to adjust dose as needed.
  • Dose adjustment during illness: reduce or increase dose based on carbohydrate intake and activity.
  • Caution in renal or hepatic impairment: may require dose modification.
  • Pregnancy and breastfeeding: only use if benefits outweigh potential risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Insulin therapy can be affected by several concomitant medicines.

Major Interactions (Avoid)

  • Other insulin products: additive hypoglycaemic effect.
  • Sulfonylureas: increased risk of severe hypoglycaemia.
  • Meglitinides: additive glucose‑lowering effect.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask hypoglycaemia symptoms.
  • ACE inhibitors: can potentiate insulin’s glucose‑lowering action.
  • Thiazide diuretics: may raise blood glucose levels.
  • Oral contraceptives: may slightly reduce insulin requirements.

Frequently Asked Questions

Insulatard is a long‑acting insulin preparation used to provide basal insulin coverage in patients with type 1 or type 2 diabetes mellitus. It helps maintain stable blood glucose levels between meals and overnight, supporting overall glycaemic control as part of a comprehensive diabetes management plan.

Insulin Human binds to insulin receptors on muscle, fat and liver cells, activating intracellular pathways that increase glucose uptake, promote glycogen synthesis, and suppress hepatic glucose production. This coordinated action lowers circulating glucose and supplies a steady insulin effect throughout the day.

The dose of Insulatard is individualized. A qualified prescriber determines the appropriate amount based on the patient’s age, weight, type of diabetes, current glycaemic control, diet, activity level and other medications. Dosing adjustments are made according to regular blood‑glucose monitoring.

Insulatard may be used in pregnancy or while breastfeeding only when the potential benefit to the mother outweighs any possible risk to the fetus or infant. The decision should be made by a healthcare professional familiar with the patient’s clinical situation.

To request Insulatard, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics) and any necessary import documentation.

Insulatard is a human insulin formulation with a relatively long duration of action, similar to other basal insulins such as insulin glargine or detemir. Compared with analogues, it may have a slightly different onset and peak profile, but it provides effective basal coverage when titrated appropriately.

Insulatard should be stored in a refrigerator at 2‑8 °C, protected from light, and must not be frozen or shaken. Once in use, the vial can be kept at room temperature (up to 30 °C) for a maximum of 28 days, after which any remaining solution should be discarded.

Insulatard is administered by subcutaneous injection, typically into the abdomen, thigh or upper arm. The injection site should be rotated to reduce the risk of lipodystrophy. Patients should follow the prescriber’s instructions regarding timing, dose and injection technique.

The most serious risks include severe hypoglycaemia, which can lead to seizures, loss of consciousness or injury, and rare allergic reactions such as anaphylaxis. Patients should be educated to recognize early signs of low blood sugar and to seek immediate medical attention if a serious reaction occurs.

Insulatard is contraindicated in individuals with a known hypersensitivity to insulin human or any of the excipients in the formulation. It should also be avoided in patients experiencing severe hypoglycaemia until the condition is corrected, and used with caution in those with renal or hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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