Product image of Insuman Basal Solostar (Insulin Human) supplied by GNH India

Insuman Basal Solostar

Active Ingredient:
Insulin Human
Origin:
EU

Insuman Basal Solostar (Insulin Human)

Insulin human, the active ingredient in Insuman Basal Solostar, is an insulin presented as a long‑acting injectable solution for subcutaneous use. It treats type 1 and type 2 diabetes mellitus in adults and children by providing basal insulin coverage.
GNH India supplies Insuman Basal Solostar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sanofi-Aventis Deutschland Gmbh

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Indications & Clinical Uses

Insuman Basal Solostar is a basal insulin used in the management of diabetes mellitus.

  • Type 1 diabetes mellitus: supplies steady basal insulin to maintain fasting glucose levels.
  • Type 2 diabetes mellitus: adds basal insulin when oral agents no longer achieve target glycaemia.
  • Insulin‑deficient states: replaces endogenous insulin to prevent hyperglycaemia and ketoacidosis.

How It Works

  • Insulin human binds to insulin receptors on muscle, adipose and hepatic cells, activating the receptor’s tyrosine kinase activity. This triggers intracellular signaling that promotes glucose uptake, glycogen synthesis and lipogenesis while inhibiting hepatic gluconeogenesis, thereby lowering blood glucose concentrations.

Side Effects

Common Side Effects

  • Hypoglycaemia: low blood glucose episodes, especially if dosing is excessive.
  • Injection‑site reactions: redness, swelling or itching at the injection site.
  • Weight gain: increased adipose tissue due to enhanced glucose utilization.
  • Lipodystrophy: localized changes in fat tissue with repeated injections.

Serious or Rare Side Effects

  • Severe hypoglycaemia: neuroglycopenic symptoms requiring immediate assistance.
  • Anaphylactic reaction: rare systemic allergic response with rash, airway swelling or hypotension.
  • Insulin antibody formation: may alter insulin action and cause unpredictable glucose control.

Precautions & Warnings

Before using Insuman Basal Solostar, consider the following precautions.

  • Blood‑glucose monitoring: check levels regularly to adjust dose safely.
  • Illness or stress: may require temporary dose increase to maintain control.
  • Existing hypoglycaemia: avoid administration until glucose is normalized.
  • Renal or hepatic impairment: use with caution as clearance may be altered.
  • Injection technique education: rotate sites and avoid intramuscular injection.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Insuman Basal Solostar may interact with other medicines.

Major Interactions (Avoid)

  • Sulfonylureas or meglitinides: combined use can cause severe hypoglycaemia.
  • Beta‑blockers: may mask hypoglycaemia symptoms, requiring closer glucose monitoring.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may increase risk of hyperkalaemia when used with insulin.
  • Thiazide diuretics: can raise blood glucose, potentially reducing insulin effectiveness.
  • Corticosteroids: may increase insulin requirements due to induced hyperglycaemia.

Frequently Asked Questions

Insuman Basal Solostar is a long‑acting insulin formulation used to provide basal insulin coverage in patients with type 1 or type 2 diabetes mellitus. It helps maintain stable fasting blood glucose levels when endogenous insulin production is insufficient or when oral antidiabetic agents no longer achieve target control.

Insulin human mimics the natural hormone insulin. It binds to insulin receptors on muscle, fat and liver cells, activating a cascade that promotes glucose uptake, glycogen synthesis and lipid storage while suppressing hepatic glucose production. This reduces circulating blood glucose and supports normal metabolic function.

The dose of Insuman Basal Solostar is individualized. A qualified prescriber determines the appropriate amount based on the patient’s age, weight, current glycaemic control, diet, activity level and concomitant therapies. Patients should follow the prescribing information and adjust only under medical supervision.

Insulin is generally considered the treatment of choice for diabetes in pregnancy because it does not cross the placenta in significant amounts. However, the safety of Insuman Basal Solostar specifically should be evaluated by the treating obstetrician and endocrinologist, and the benefits and risks discussed with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling) and any required import documentation.

Insuman Basal Solostar contains human insulin, whereas many newer basal insulins are insulin analogues with altered pharmacokinetics. Human insulin has a well‑established safety profile and is often less expensive, but analogue products may offer flatter glucose‑lowering curves and reduced risk of nocturnal hypoglycaemia for some patients.

The product should be stored at 2‑8 °C (refrigerated) in its original carton, protected from light. Do not freeze or shake the vial. Once in use, it may be kept at room temperature (up to 30 °C) for a limited period as specified in the package insert, but must be discarded after the recommended in‑use time.

Insuman Basal Solostar is administered by subcutaneous injection, typically into the abdomen, thigh or upper arm. The injection should be given once daily at the same time each day, with site rotation to reduce lipodystrophy. Patients must be trained on proper technique and needle disposal.

The most serious risks include severe hypoglycaemia, which can cause seizures, loss of consciousness or death if not treated promptly, and rare allergic reactions such as anaphylaxis. Patients should be educated to recognize early signs of hypoglycaemia and to have rapid‑acting carbohydrate sources available.

Insuman Basal Solostar is contraindicated in individuals with a known hypersensitivity to human insulin or any excipients in the formulation. It should also be avoided in patients experiencing hypoglycaemia until glucose levels are corrected, and used with caution in those with severe renal or hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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